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[PDF] Top 20 Notch signaling restricts FGF pathway activation in parapineal cells to promote their collective migration

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Notch signaling restricts FGF pathway activation in parapineal cells to promote their collective migration

Notch signaling restricts FGF pathway activation in parapineal cells to promote their collective migration

... How Notch signaling could modulate FGF pathway activity in parapineal cells remains an open ...display parapineal migration defects similar to mib -/- ... Voir le document complet

24

Left/right asymmetric collective migration of parapineal cells is mediated by focal FGF signaling activity in leading cells

Left/right asymmetric collective migration of parapineal cells is mediated by focal FGF signaling activity in leading cells

... of cells to collectively interpret surrounding environ- mental signals underpins their capacity to coordinate their migra- tion in various contexts, including embryonic ... Voir le document complet

11

Interaction entre les voies de signalisation FGF et Notch lors de la migration de la parapineale dans le cerveau asymétrique du poisson zèbre

Interaction entre les voies de signalisation FGF et Notch lors de la migration de la parapineale dans le cerveau asymétrique du poisson zèbre

... of cells to collectively interpret surrounding environ- mental signals underpins their capacity to coordinate their migra- tion in various contexts, including embryonic ... Voir le document complet

236

Vitamin D deficiency down-regulates Notch pathway contributing to skeletal muscle atrophy in old wistar rats

Vitamin D deficiency down-regulates Notch pathway contributing to skeletal muscle atrophy in old wistar rats

... lysed in an ice-cold lysis buffer (50 mM HEPES pH ...Prior to SDS-PAGE, proteins were dissolved in a denaturing buffer containing ...transferred to a polyvinylidene membrane (Millipore, ... Voir le document complet

14

Adherens junction remodeling by the Notch pathway in Drosophila melanogaster oogenesis.

Adherens junction remodeling by the Notch pathway in Drosophila melanogaster oogenesis.

... 16 cells (one oocyte and 15 nurse cells [NCs]) sur- rounded by a monolayer of follicular cells ...somatic cells can be identifi ed: the polar cells, the stalk cells, and the ... Voir le document complet

12

Vitamin D deficiency down-regulates Notch pathway contributing to skeletal muscle atrophy in old Wistar rats

Vitamin D deficiency down-regulates Notch pathway contributing to skeletal muscle atrophy in old Wistar rats

... stimulated in satellite cells and myofibers. Delta-like binds to Notch receptor which activates Notch ...the Notch receptor and generating a transmembrane fragment of ... Voir le document complet

2

Adherens junction remodeling by the Notch pathway in Drosophila melanogaster oogenesis.

Adherens junction remodeling by the Notch pathway in Drosophila melanogaster oogenesis.

... process. In order to test this, somatic mutant clones for a shg null allele (shg R69 ) and for a sqh hypomorphic allele (sqh 1 ) were ...StC in the mutant region than in WT (n=12) ...delay ... Voir le document complet

51

Activation of the NF kappa B Pathway Enhances AhR Expression in Intestinal Caco-2 Cells

Activation of the NF kappa B Pathway Enhances AhR Expression in Intestinal Caco-2 Cells

... reproduction in any medium, provided the original work is properly ...role in the regulation of xenobiotic metabolizing enzymes, AhR is also involved in ...expression in Caco-2 cells. ... Voir le document complet

9

Exosomal Lipids Impact Notch Signaling and Induce Death of Human Pancreatic Tumoral SOJ-6 Cells

Exosomal Lipids Impact Notch Signaling and Induce Death of Human Pancreatic Tumoral SOJ-6 Cells

... functioning to inhibit the Notch-1 survival pathway leading to the activation of PTEN and GSK-3b, the decrease in Hes-1 expression and drives SOJ-6 cells towards the ... Voir le document complet

18

Activation of the Cph1-Dependent MAP Kinase Signaling Pathway Induces White-Opaque Switching in Candida albicans.

Activation of the Cph1-Dependent MAP Kinase Signaling Pathway Induces White-Opaque Switching in Candida albicans.

... [7]. To investigate if the core positive regulators were required for Ste11/Cph1-induced white- opaque switching, we expressed CPH1 and the hyperactive STE11 DN467 allele in mutants of strain WO-1 from ... Voir le document complet

18

Activation of the Yeast Hippo Pathway by Phosphorylation-Dependent Assembly of Signaling Complexes

Activation of the Yeast Hippo Pathway by Phosphorylation-Dependent Assembly of Signaling Complexes

... A to C) revealed that Nud1 T78 was especially critical for MEN signaling, with two additional residues, S53 and S63, contributing to this ...overexpressed in the presence of wild-type NUD1 ... Voir le document complet

11

Tankyrases Promote Homologous Recombination and Check Point Activation in Response to DSBs

Tankyrases Promote Homologous Recombination and Check Point Activation in Response to DSBs

... shown to be required for the integrity of the BRCA1A complex containing RAP80, BRCA1, BRCC36 and CCDC98 [ 24 ] [ 25 ...loaded to chromatin bound by TNKS1. We indeed found that RAP80 was recruited to ... Voir le document complet

27

CRF2 signaling is a novel regulator of cellular adhesion and migration in colorectal cancer cells.

CRF2 signaling is a novel regulator of cellular adhesion and migration in colorectal cancer cells.

... conforms to French ...consent to the use of tissue samples for research purposes; in the absence of informed consent, tissue samples from patients known to be deceased could also be used for ... Voir le document complet

37

A redox-sensitive signaling pathway mediates pro-angiogenic effect of chlordecone via estrogen receptor activation

A redox-sensitive signaling pathway mediates pro-angiogenic effect of chlordecone via estrogen receptor activation

... contribute to increased VEGF ...example in hypoxia, O2 − generated from mitochondria clustering in close proximity to the nucleus hypoxia has been shown to stimulate VEGF expression by ... Voir le document complet

16

B Cells Promote Pancreatic Tumorigenesis

B Cells Promote Pancreatic Tumorigenesis

... – to demonstrate that BTK regulates B cell and macrophage-mediated T cell suppression in PDAC ...shown to exhibit high BTK activation in tumor-resident B cells and ... Voir le document complet

10

Activation de la voie Notch par OTT-MAL dans les leucémies aiguës mégacaryoblastiques

Activation de la voie Notch par OTT-MAL dans les leucémies aiguës mégacaryoblastiques

... signalisation Notch Sur un plan mécanistique, nous avons montré que la protéine OTT-MAL inte- ragit directement avec RBPJ et active de façon anormale la transcription des gènes cibles de ... Voir le document complet

3

Cutting edge: abortive proliferation of CD46-induced Tr1-like cells due to a defective Akt/Survivin signaling pathway.

Cutting edge: abortive proliferation of CD46-induced Tr1-like cells due to a defective Akt/Survivin signaling pathway.

... Tr1 cells undergo abortive proliferation caused by a defect of cell cycle progression associated with a death of proliferating ...Akt pathway in human Tr1-like cells explain this particular ... Voir le document complet

26

Evolutionary conservation of Notch signaling inhibition by TMEM131L overexpression

Evolutionary conservation of Notch signaling inhibition by TMEM131L overexpression

... the Notch pathway in the Drosophila system, we next examined whether this is also the case in ...IgDll4 to activate Notch1 signaling pathway. The cells were then ... Voir le document complet

8

EGFR activation and signaling in cancer cells are enhanced by the membrane-bound metalloprotease MT4-MMP.

EGFR activation and signaling in cancer cells are enhanced by the membrane-bound metalloprotease MT4-MMP.

... BT549) cells, epidermoid cancer A431 cells, Hela cells and monkey epithelial COS-1 cells were purchased from American Type Culture Collection ...MDA-MB-435 cells were kindly provided by ... Voir le document complet

37

Migration collective de cellules épithéliales

Migration collective de cellules épithéliales

... la migration collective d’un point de vue expérimental, et en particulier par l’identification des facteurs gouvernant réellement ce processus et ceux ne jouant qu’un rôle ... Voir le document complet

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