[PDF] Top 20 Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): a randomised controlled trial

... summarises the incidence of serious adverse events that arose in more than 1% of ...adverse events in the pioglitazone group than in the placebo ... Voir le document complet

... Objective: In this post hoc analysis, we examined insulin requirements and regimens, glycemic control, cardiovascular outcomes, and safety in the patients treated with insulin at ... Voir le document complet

... Methods: PROactive was a randomised, double-blind, placebo-controlled outcome study in patients with type 2 diabetes and macrovascular ... Voir le document complet

... From the Division of Diabetes, Nutrition and Metabolic Disorders, Department of Medicine, CHU Sart Tilman, Liège, ...Belgium. The secondary analysis of the ... Voir le document complet

... quality of life, especially physical functioning, which points to a positive effect of the drug on this health-related ...tolerated in this study, with adverse ... Voir le document complet

... Acknowledgements The authors wish to thank the patients who were accepted to participate in the study, as well as Jeremy Jove and Regis Lassalle (Department of ... Voir le document complet

... concentrations of canagliflozin did not inhibit or induce key CYP isoenzymes in vitro, and there was no clinically relevant impact of canagliflozin on CYP3A4 in vivo [ 7 ...(and, in ... Voir le document complet

... USA, 2-Neuropsychiatric Research Institute, Fargo, ND, USA, 3-University of Liège, Liège, Belgium OBJECTIVES: To evaluate the impact of the first selective cannabinoid type 1 ... Voir le document complet

... loss. In addition, patients with T2DM have experienced remission of hyperglycaemia or a reduced need for ...alter the passage of food in the ...LAGB ... Voir le document complet

... accelerate the clinical course of chronic HCV infection, significantly increasing the risk of fibrosis and its progression to cirrhosis, decompensation and HCC [15- ...shown a link ... Voir le document complet

... on trial recruitment and whether or not we should stop the trial ...earlier. The DMC did not un-blind the data and suggested extending the recruitment period by one year to ... Voir le document complet

... Pain in 4 questions” Neuropathic pain in four questions is a clinical tool for the diagnosis of neuropathic pain ...to the interview (that is, symptoms) and to the sensory ... Voir le document complet

... Gaal 2 1 Division of Diabetes, Nutrition, and Metabolic Disorders, Department of Medicine, CHU Sart Tilman (B35), University of Liège, B-4000 Liège, Belgium 2 Department ... Voir le document complet

... Oberman A, Rutan GH, Stamler J: Effect of diuretic-based antihypertensive treatment on cardiovascular disease in older diabetic patients with isolated systolic ...for the ALLHAT ... Voir le document complet

... treat. In order to prevent attrition bias, imputation of the missing data is ...planned. The statistical analysis plan also provides for an additional per- protocol ...to the normality ... Voir le document complet

... Risk of cardiovascular disease and all cause mortality among patients with type 2 diabetes prescribed oral antidiabetes drugs: retrospective cohort study using UK general ... Voir le document complet

... dIssEMInAtIon The ObesiStress protocol complies with the ethics guide- lines for clinical research and has been approved by the ethics committee (Comités de Protection des Personnes, Sud- Est ... Voir le document complet

... schools in February 2012 were invited to take part in the ...as the Substance Use Risk Profile Scale (SURPS), a 23-item questionnaire that assesses personality along four dimensions: ... Voir le document complet

... discontinuation of treatment, all groups returned towards baseline values over the following four ...Inspection of fig 1 does not suggest any difference in the pattern of onset ... Voir le document complet

... behaviour of the patients was carefully monitored, scored daily by the team psychologist, and documented on the case report form for the two days before drug administration, on ... Voir le document complet