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[PDF] Top 20 Role of the tumor microenvironment in regulating apoptosis and cancer progression

Has 10000 "Role of the tumor microenvironment in regulating apoptosis and cancer progression" found on our website. Below are the top 20 most common "Role of the tumor microenvironment in regulating apoptosis and cancer progression".

Role of the tumor microenvironment in regulating apoptosis and cancer progression

Role of the tumor microenvironment in regulating apoptosis and cancer progression

... as the main component of tumor stroma, have been found to be highly activated in ...These cancer-associated fibroblasts (CAFs) contribute to the progression of many ... Voir le document complet

25

An Eight-Gene Hypoxia Signature Predicts Survival in Pancreatic Cancer and Is Associated With an Immunosuppressed Tumor Microenvironment

An Eight-Gene Hypoxia Signature Predicts Survival in Pancreatic Cancer and Is Associated With an Immunosuppressed Tumor Microenvironment

... hypoxia in PDA deters the establishment of an effective anti-tumor response ( 4 , 16 , 17 , 39 – 41 ...eighteen-gene tumor in flammation signature ( 52 ), we showed that tumors ... Voir le document complet

17

Colon-specific immune microenvironment regulates cancer progression versus rejection

Colon-specific immune microenvironment regulates cancer progression versus rejection

... polarization in a progressive CRC tumor microenvironment or an antitumor polarization in a rejecting CRC tumor ...microenvironment. In line with other studies on colonic ... Voir le document complet

15

The hypoxic tumor microenvironment regulates the LPA signaling axis to promote cancer cell invasion and metastasis

The hypoxic tumor microenvironment regulates the LPA signaling axis to promote cancer cell invasion and metastasis

... promotes tumor progression and whose expression is upregulated in various cancers (Benesch et ...1999). In contrast, important LPA degrading enzymes, the LPPs, are downregulated ... Voir le document complet

173

Latest Advances in Targeting the Tumor Microenvironment for Tumor Suppression

Latest Advances in Targeting the Tumor Microenvironment for Tumor Suppression

... by the BLZ945 inhibitor could lead to the switch of the TAM phenotype toward an anti-tumor phenotype in a glioma preclinical model thanks to GM-CSF and IFN-γ produced by ... Voir le document complet

35

Latest Advances in Targeting the Tumor Microenvironment for Tumor Suppression

Latest Advances in Targeting the Tumor Microenvironment for Tumor Suppression

... by the BLZ945 inhibitor could lead to the switch of the TAM phenotype toward an anti-tumor phenotype in a glioma preclinical model thanks to GM-CSF and IFN-γ produced by ... Voir le document complet

35

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en fr The influence of hypoxia on podoplanin expression in cancer-associated fibroblasts (CAF) and its role in the progression of breast cancer L'influence de l'hypoxie sur l'expression de podoplanine dans les fibroblastes associés au cancer (CAF) et son rôle dans la progression du cancer du sein

... resistance of cancer cells in comparison to co-culture of cancer cells with control ...However, the molecular mechanism of podoplanin action in tumor ... Voir le document complet

142

Apoptosis mapping in space and time of 3D tumor ecosystems reveals transmissibility of cytotoxic cancer death

Apoptosis mapping in space and time of 3D tumor ecosystems reveals transmissibility of cytotoxic cancer death

... promotes the death of nearby cancer cells, suggesting the release of diffusible factors which amplify the initial cytotoxic ...summary The tumor ... Voir le document complet

24

Never Travel Alone: The Crosstalk of Circulating Tumor Cells and the Blood Microenvironment

Never Travel Alone: The Crosstalk of Circulating Tumor Cells and the Blood Microenvironment

... Interaction of CTCs with Neutrophils The role of neutrophils in cancer progression has been extensively studied recently [ 24 , 25 ...levels of circulating ... Voir le document complet

13

The Adipose Microenvironment Dysregulates the Mammary Myoepithelial Cells and Could Participate to the Progression of Breast Cancer

The Adipose Microenvironment Dysregulates the Mammary Myoepithelial Cells and Could Participate to the Progression of Breast Cancer

... 5286, Cancer Research Center of Lyon, Lyon, France, 3 Université Paris-Saclay, CEA, INRAE, Département Médicaments et Technologies pour la Santé (DMTS), MetaboHUB, Gif-sur-Yvette, France, 4 Banque de Tissus ... Voir le document complet

16

Chronic cisplatin treatment promotes enhanced damage repair and tumor progression in a mouse model of lung cancer

Chronic cisplatin treatment promotes enhanced damage repair and tumor progression in a mouse model of lung cancer

... arrest and apoptosis profiles in response to cisplatin compared to controls (Supp ...response in vivo is not dependent on the p53-p21 ...investigate the kinetics of ... Voir le document complet

37

Focus on the target: the tumor microenvironment, Society for Immunotherapy of Cancer Annual Meeting Workshop, October 24th-25th 2012

Focus on the target: the tumor microenvironment, Society for Immunotherapy of Cancer Annual Meeting Workshop, October 24th-25th 2012

... only the tumor micro- environment before and after vaccination, but also to con- sider the microenvironment of immune priming at the vaccine site ...used in ... Voir le document complet

11

Evolution of Mutational Landscape and Tumor Immune-Microenvironment in Liver Oligo-Metastatic Colorectal Cancer

Evolution of Mutational Landscape and Tumor Immune-Microenvironment in Liver Oligo-Metastatic Colorectal Cancer

... PTs and MTs in group A. Phenolyzer tool was applied in order to evidence the most dominant and interrelated ...APC and TP53, which have a defined role in CRC [ 28 ... Voir le document complet

17

Tumor Microenvironment Autophagic Processes and Cachexia: The Missing Link?

Tumor Microenvironment Autophagic Processes and Cachexia: The Missing Link?

... University of Rome, Rome, Italy Cachexia is a syndrome that affects the entire organism and presents a variable plethora of symptoms in patients, always associated with continuous ... Voir le document complet

8

Elucidating the role of the family of GalNAc-Transferases in aberrant protein O-glycosylation in the progression of epithelial ovarian cancer

Elucidating the role of the family of GalNAc-Transferases in aberrant protein O-glycosylation in the progression of epithelial ovarian cancer

... Additionally, the epithelial–mesenchymal transition (EMT) pathway is also another factor that promotes the invasive and migratory capacity of EOC cells ...to the generation of ... Voir le document complet

303

Application of the single cell genomics in deciphering tumor heterogeneity and its role in tumor progression and drug resistance

Application of the single cell genomics in deciphering tumor heterogeneity and its role in tumor progression and drug resistance

... reproducibly in this cancer model, suggesting the existence of programs governing the emergence and maintenance of ...outcome of underlying genetic variation, ... Voir le document complet

152

Mesenchymal Stem Cell Administration Attenuates Colon Cancer Progression by Modulating the Immune Component within the Colorectal Tumor Microenvironment

Mesenchymal Stem Cell Administration Attenuates Colon Cancer Progression by Modulating the Immune Component within the Colorectal Tumor Microenvironment

... Polarization of immune cells • Cell therapy • Radiotherapy • Pelvic radiation disease A BSTRACT We here determine the in fluence of mesenchymal stem cell (MSC) therapy on the ... Voir le document complet

17

Breast Cancer Cell Invasion into a Three Dimensional Tumor-Stroma Microenvironment

Breast Cancer Cell Invasion into a Three Dimensional Tumor-Stroma Microenvironment

... 1 In this study, to model 3D chemotactic tumor-stroma invasion in vitro, we developed an innovative microfluidic chip allowing side-by-side positioning of 3D hydrogel-based ...extended ... Voir le document complet

19

Thalidomide radiosensitizes tumors through early changes in the tumor microenvironment

Thalidomide radiosensitizes tumors through early changes in the tumor microenvironment

... Superficial tumor perfusion was assessed using a laser Doppler imager (Moor Instruments, Millwey, United Kingdom) after 2 days of treatment with thalidomide or ...vehicle. The skin was depilated ... Voir le document complet

8

Study of the role of the p16INK4a gene in tumor progression and tissue regeneration/function following exposure to ionizing radiation

Study of the role of the p16INK4a gene in tumor progression and tissue regeneration/function following exposure to ionizing radiation

... long-term, in at least a subset of oncogenically activated cells. In fact, inactivation of p16 INK4a in these cells may have directly lead to cancer progression and ... Voir le document complet

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