[PDF] Top 20 Role of 17β-hydroxysteroid dehydrogenase type 5 in breast cancer studied by intracrinology
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Role of 17β-hydroxysteroid dehydrogenase type 5 in breast cancer studied by intracrinology
... expressed in human tissues including mammary ...reduction of Δ4-androstenedione (4-DIONE) into testosterone ...aromatization by CYP19 aromatase provides a route for E2 biosynthesis independent ... Voir le document complet
190
Substrate inhibition of 17 beta-hydroxysteroid dehydrogenase type 1 in living cells and regulation among the steroid-converting enzymes in breast cancers
... inhibition of 17β-HSD1with E1 has been proved using the purified enzyme ...a role in living ...if 17β-HSD1 activity in estrone conversion was influenced by DHT ... Voir le document complet
200
Function and regulation of 17B-hydroxysteroid dehydrogenase type7 (17B-HSD7) in sex hormone biosynthesis and breast cancer : in vitro, in vivo, proteomic and three dimensional co-culture studies
... 1.5.2 17β-HSD1 17β-HSD1 is the first identified enzyme in 17β-HSDs ...impact in the biosynthesis of estrogens had been demonstrated since 1950 ...(68). In 1993, Zhu et al ... Voir le document complet
220
Étude de l'action du PBRM, un inhibiteur de la 17β-hydroxystéroïde déshydrogénase (17β--HSD) type 1 : ...qui mena à la découverte fortuite d'un 1er activateur de la 17β-HSD type 12
... discovery, 17β-hydroxysteroid dehydrogenase type 12 (17 -HSD12) still remains relatively ...one of the most recently identified isoenzymes of the 17 -HSD family, a group ... Voir le document complet
164
Expression and role of 17BETA-hydroxysteroid dehydrogenase type 1, 5 and 7 in epithelial ovarian cancer
... Ovarian cancer has the highest mortality rate among gynaecological ...lung, breast and colorectal cancer are the most common causes of cancer death among women in the United ... Voir le document complet
146
Critical role for lysyl oxidase in mesenchymal stem cell-driven breast cancer malignancy
... localization of CD44 in MDA-MB-231 and MDA-MB-231 MSC ...analyses in- dicated that the interaction of MSCs with cancer cells caused a marked increase in CD44 localization to the ... Voir le document complet
7
Dual SIRT1 expression patterns strongly suggests its bivalent role in human breast cancer
... mating type information regulation 2 homolog 1 (SIRT1), the mammalian counterpart of yeast silent information regulator 2 (Sir2), is the most extensively studied protein in the SIRT ... Voir le document complet
9
Role of stable free radicals in conjugated antioxidant and cytotoxicity treatment of triple negative breast cancer
... analysis of current TNBC treatments found that bevacizumab, carboplatin, and paclitaxel treatment was the most likely to improve the overall response rate in TNBC patients and in advanced metastatic ... Voir le document complet
22
A refined molecular taxonomy of breast cancer.: molecular classification of breast cancer
... dissemination of sci- entific research documents, whether they are pub- lished or ...institutions in France or abroad, or from public or private research ... Voir le document complet
2
Comparative transductions of breast cancer cells by three DNA viruses.
... dissemination of sci- entific research documents, whether they are pub- lished or ...institutions in France or abroad, or from public or private research ... Voir le document complet
4
Expression of Galectin-7 Is Induced in Breast Cancer Cells by Mutant p53
... marker of epithelial differentiation expressed in the stratified epithelium of various ...members of the galectin family, its expression level is often significantly altered in ... Voir le document complet
10
p53 mutant breast cancer patients expressing p53γ have as good a prognosis as wild-type p53 breast cancer patients.
... degree of interdependence between the variables p53b, p53g and p53 mutation with respect to survival and cancer recurrence, we aggregated these variables into combined variables and reran the CR ...results ... Voir le document complet
11
Induction by estrogens of methotrexate resistance in MCF-7 breast cancer cells
... for 5 days, and then the RNA was isolated using the acid guanidium–thiocyanate extraction method ...Aliquots of 15 µ g of RNA was separated on a 1% agarose–2% formaldehyde denaturing gel and ... Voir le document complet
8
Defining the role of aromatase inhibitors in the adjuvant endocrine treatment of early breast cancer
... group of 24 breast cancer experts review efficacy and safety data from the recent major trials investigating tamoxifen and the third-generation AIs in postmenopausal women, which have ... Voir le document complet
11
Transcriptome-wide analysis of natural antisense transcripts shows their potential role in breast cancer.
... values in the four categories, corresponding to one third of the patient ...standpoints. In this group of 4884 transcript pairs, the number of tumor ncNAT read counts increased compared ... Voir le document complet
12
5-fluorouracil degradation rate (5-FU-DR) could predict toxicity in breast cancer patients treated with capecitabine.
... used in metastatic breast cancer after anthracyclines and/or taxanes failure or in frail ...identification of a toxicity predictive biomarker could help to avoid severe toxicities and ... Voir le document complet
1
Quantitative evaluation of Therapeutic response by FDG-PET–CT in Metastatic Breast Cancer
... element in each of the two ...volumes of inter- est (VOIs) were registered using a rigid transformation (three translation and three rotation parameters) derived from block- matching registration ( ... Voir le document complet
11
Quantification of HER family receptors in breast cancer
... homodimers in formalin-fixed, paraffin-embedded (FFPE) tissue specimens ...quantification of proteins and protein-protein complexes through the release of a fluorescent tag (VeraTag reporter, ... Voir le document complet
13
Detection of Hoxa1 Expression in Human Breast Cancer
... specimens. Breast cancer samples as well as normal adjacent tissues were collected from patients treated for surgery (Hospital Clinic, Villarroel, 170, Barcelona, Spain) and were immediately frozen ... Voir le document complet
6
Signaling pathway switch in breast cancer.
... downstream of the PI3K/AKT and JUN/MAPK cascades. FOXOs play a major role in the regulation of both the cell cycle and metabolism ...activated by the JUN kinase signaling pathway ... Voir le document complet
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