Haut PDF The role of histone variant H2A.Z in the regulation of gene expression in breast cancer cells
The role of histone variant H2A.Z in the regulation of gene expression in breast cancer cells
... Transcription regulation of the p21 gene is mediated by dynamic binding of the histone variant ...within the p21 promoter region in p53 positive ...
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Histone variants H2A.Z and H3.3 coordinately regulate PRC2-dependent H3K27me3 deposition and gene expression regulation in mES cells
... deposition in mES cells Histone variant ...roles in gene silencing and hetero- chromatin [ 23 , 24 ...impairs the folding of nucleosomal arrays but also counteracts ...
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SIRT1-dependent epigenetic regulation of H3 and H4 histone acetylation in human breast cancer
... complexity of carcinogenesis cannot be represented by genetic mutations alone, but also involves profound epigenetic ...alterations. The epigenetic regulation of the genome includes ...
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Breaking down the Contradictory Roles of Histone Deacetylase SIRT1 in Human Breast Cancer
... Department of Biopathology, Centre Jean Perrin, 58 Rue Montalembert, 63011 Clermont-Ferrand, France * Correspondence: ...Abstract: Breast cancer (BC) is the most common type of ...
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The Complex Subtype-Dependent Role of Connexin 43 (GJA1) in Breast Cancer.
... allow the transfer of small molecules between the cytoplasm of adjacent ...that the role of Connexin 43 (Cx43) in cancer is tissue- and stage-specific and ...
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Quantification of hypoxia-related gene expression as a potential approach for clinical outcome prediction in breast cancer
... result in activation of HIF factors, followed by increased transcription of hypoxia- related genes and the development of a more aggressive breast ...performed in ...
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Detection of Hoxa1 Expression in Human Breast Cancer
... regulate the coordinated expression of mul- tiple genes involved in development, differentiation and malignant ...understand the role played by these proteins in ...
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Analysis of HER2 genomic binding in breast cancer cells identifies a global role in direct gene regulation
... binding of HER2 to the chromatin is linked to dimerization with ...to the nucleus in human squamous carcinoma and breast cancer cells [ 25 ...]. In support ...
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The role of GABARAPL1/GEC1 in autophagic flux and mitochondrial quality control in MDA-MB-436 breast cancer cells.
... assay The quantification of GSH in our 2 cell lines was performed according to the protocol previously ...MDA-MB-436-sh2 cells were plated in 6-well plates (600,000 per well) and ...
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Defining the role of aromatase inhibitors in the adjuvant endocrine treatment of early breast cancer
... tamoxifen in postmenopausal women, either as initial therapy or as an alternative for women who have started adjuvant therapy with ...regarding the best way to use AIs, such as the optimal length ...
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The role of CD23 in the regulation of allergic responses
... by the IgG subclass present in the ...geting of the immune ...a role in that study. Potentially, the co-ligation of FcγRs with CD23 could impact complex ...
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A splice site variant in the bovine RNF11 gene compromises growth and regulation of the inflammatory response.
... product in all examined tissues, and showed by sequencing that it encompassed the expected exon 2 sequence (data not ...shown). The same experiment performed with RNA from a homozygous mutant GG ...
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Germline mutation in the RAD51B gene confers predisposition to breast cancer.
... candidate gene for breast cancer predisposition but no mutation was detected in a study of 188 multiple breast cancer fam- ily cases (Johnson et ...[20]). The low ...
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Role of XPC in the human cutaneous cancer cells invasion
... and cancer. In human epithelial cancers such as SCC, invasive cells are typically observed to migrate collectively (Friedl and Gilmour ...2009). In collective invasion, carcinoma cells ...
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Role of estrogens and their receptors in adhesion and invasiveness of breast cancer cells.
... are in agreement with an anti- invasive effect of estrogens. Role of estrogen receptor variants in cancer progression? Numerous studies have identified ERα and ERα variants from ...
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Feature selection from gene expression data : molecular signatures for breast cancer prognosis and gene regulation network inference
... this in mind, many groups have tackled this stability or robustness issue, (see, ...borrowed in this thesis for experimentation has ...one of the main reasons why so many ...
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en fr Role of the histone variant H2A.Z and its isoform in the control of intestinal epithelial homeostasis Contrôle de l'homéostasie épithéliale intestinale par la dynamique des isoformes du variant d'histone H2A.Z
... qu’une expression diminuée des marqueurs de différenciation entérocytaire, notamment Lph et Alpi (Alcaline phosphatase ...faible expression de Cdx2 dans ces ...résultats in vivo abondent dans le sens ...
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Involvement of retinoblastoma protein and HBP1 in histone H1(0) gene expression.
... analysis of factors interacting with histone H4 site II, known to be involved in the S- phase-dependent activation of histone H4 genes (24, 43), showed the obvious link ...
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Role of CD4+ T cells in the regulation of the immune response against encapsulated Group B Streptococcus
... types of MHC molecules: MHC class I and MHC class ...mammalian cells and mediates peptide recognition by CD8+ T cells ...T cells (Figure ...(121). In this setting, exogenous antigens ...
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Study of a new splice variant of Neuropilin-1: antagonistic functions in the regulation of cancer progression?
... Proliferation of PC3 transfected with either NRP1-FS or –Δ7 was evaluated by DNA ...added in the culture medium (day 0) and cells were harvested 1, 3 or 5 days ...expressing cells ...
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