[PDF] Top 20 Role of Hedgehog Signaling in Vasculature Development, Differentiation, and Maintenance

... expression in triple-negative breast cancers [ 87 ] while Ihh expression has been associated with Vegf expression and CD34 staining in hepatocellular carcinoma [ 88 ...Hyperactivation of Hh ... Voir le document complet

... The role of ß-catenin signaling in mesodermal lineage formation and differentiation has been ...the role of ß-catenin signaling in these processes, we ... Voir le document complet

... 1,2 and Fackson Mwale 1,2* Abstract Introduction: We previously showed that type X collagen, a marker of late stage chondrocyte hypertrophy (associated with endochondral ossification), is constitutively ... Voir le document complet

... The Hedgehog (Hh) signaling pathway plays a critical role in the patterning, differentiation and growth of a wide array of cell types during development ... Voir le document complet

... (VCAM) and b4-a1-integrin play a crucial role in this process, which is completed around ...array of signaling pathways work together to drive: (1) epicardial epithelial to mesenchymal ... Voir le document complet

... plethora of cellular pathways, as indicated by the roles of ROS in cell plasticity, tissue regeneration, and wound healing, as well as the imbalance of ROS homeostasis in ... Voir le document complet

... advances in the understanding of the molecular control of intestinal epithelial cell ...understanding of endoderm development, intestinal epithelium differentiation, and ... Voir le document complet

... production of IAHC is restricted to the ventral part of the fused dorsal aorta, whose origin is splanchnopleural ...instrumental in demonstrating the cellular and molecular bases of ... Voir le document complet

... levels in Drosophila brain extracts were determined by HPLC coupled to electrochemical detection essentially as described ( Hardie and Hirsh, 2006 ) using a mobile phase containing 4 mM decanesulfonic acid, ... Voir le document complet

... vascular development is characterized by sequential steps of vasculogenesis, angiogenesis, and in some organs, ...barriergenesis. In the CNS, the blood- brain barrier (BBB) is composed ... Voir le document complet

... expression of a 88 amino acids- truncated but catalytically inactive Rasa3 protein ...subcutaneous and intraparenchymal hemorrhages probably consecutive to abnormal adherens junctions between capillary ... Voir le document complet

... DAdKO and control male mice were castrated at 5 months, and their adrenal phenotypes were evaluated 2 months later (Figure ...expected, in control males, castration at 2 months was sufficient to ... Voir le document complet

... (and/or Hedgehog pathway) could participate in the pruning of redundant and/or abnormal ...type of nerve injury. For instance, in a crush injury the architecture of ... Voir le document complet

... action of SAG on GABAergic synaptic currents reveals one plausible mechanism underlying Shh-Smo modulation of GDP frequency in the maturing ...response in pyramidal cells remains to be ... Voir le document complet

... Gonads and adrenals The SF-1 and ELP isoforms were knocked-out in mice by three teams simultaneously ...observed in normal proportions at birth, but die by eight days because of acute ... Voir le document complet

... reported in olfactory sensitivity with females being better able than males to detect male-derived ...concentrations of the volatile male pig pheromone, androstenone, as a discriminative stimulus in ... Voir le document complet

... Kelberman and Dattani 2008), les hormones hypophysaires sont détectées à des concentrations normales à l’exception d'un déficit de l’expression de GH et occasionnellement des concentrations anormales de FSH et LH ... Voir le document complet

... protein of the GAP1 family which targets Ras and ...results in early embryonic lethality 1 ...results in a lethal syndrome characterized by severe defects during megakaryopoiesis, ... Voir le document complet

... expression of HDAC7 in the vascular endothelium during mouse embryogen- ...inactivation of the HDAC7 gene in a ubiquitous or endothelial specific manner had dramatic conse- quences on vascular ... Voir le document complet

... thought of primarily as a nuclear protein, but it also exists in the cytoplasm (Fulcher et ...validate and further explore the mitochondrial localization of pRB, we first fractionated IMR90 ... Voir le document complet