Top PDF Role of EFNBs and EphB4 in T cell development and function

Role of EFNBs and EphB4 in T cell development and function

Role of EFNBs and EphB4 in T cell development and function

... component of thymic stroma, and interaction between TECs and thymocytes is vital in positive and negative thymocyte selection [147-149] ...consequences in thymocyte ...

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Role of Hedgehog Signaling in Vasculature Development, Differentiation, and Maintenance

Role of Hedgehog Signaling in Vasculature Development, Differentiation, and Maintenance

... expression in triple-negative breast cancers [ 87 ] while Ihh expression has been associated with Vegf expression and CD34 staining in hepatocellular carcinoma [ 88 ...Hyperactivation of Hh ...

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Towards the development and validation of biomaterial surfaces and scaffolds suitable for pancreatic beta-cell development and function

Towards the development and validation of biomaterial surfaces and scaffolds suitable for pancreatic beta-cell development and function

... biomolecules and/or the seeding of ...roughness and heterogeneity can go unnoticed with ...misconceptions and complexities of water contact angle measurements are ...phase in the ...

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Role of transcription factor KLF11 and its diabetes-associated gene variants in pancreatic beta cell function

Role of transcription factor KLF11 and its diabetes-associated gene variants in pancreatic beta cell function

... a Role in Glucose Signaling in Pancreatic Beta ...expressed in human pancreatic islets and in the pancreatic beta cell lines HIT-T15, INS832 兾13, ␤TC3, and Min6 ...

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Novel insights into the role of fetal hemoglobin in spleen function, red cell survival and ineffective erythropoiesis in sickle cell disease

Novel insights into the role of fetal hemoglobin in spleen function, red cell survival and ineffective erythropoiesis in sickle cell disease

... variables and with proportions for categorical ...occurrence of a severe SCA-related event was used as a composite ...use of Kaplan-Meier curves, using the log-rank test to com- pare two ...date ...

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Role of lipid phosphate phosphatase 3 in human aortic endothelial cell function

Role of lipid phosphate phosphatase 3 in human aortic endothelial cell function

... family. In humans, three PAP genes are known: PPAP2A, PPAP2C and PPAP2B, which encode LPP1, LPP2 and LPP3, respectively 8,9 ...found in both plasma and intracellular ...side of ...

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The role of ERα36 in development and tumor malignancy

The role of ERα36 in development and tumor malignancy

... region of the ESR1 gene spans over 300 kb and consists of 10 exons and nine introns, which are the source of four isoforms: ERα66, ERα46, ERα36, and ...form of ERα, called ...

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MicroRNAs in brain development and function: a matter of flexibility and stability

MicroRNAs in brain development and function: a matter of flexibility and stability

... DETERMINATION OF NEURONAL FATE A key feature of brain development is that common neural stem cells are able to generate a large diversity of cell ...The role of microRNAs ...

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The roles of STRA6, EFNB1/B2 and ARMC5 in T cell function and autoimmune diseases

The roles of STRA6, EFNB1/B2 and ARMC5 in T cell function and autoimmune diseases

... T-cell development and present reduced numbers of peripheral T cells in lymphoid organs ...T cell-dependent disease model. Novel findings in our present work are that, on ...

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Serine Phosphorylation of SLP76 Is Dispensable for T Cell Development but Modulates Helper T Cell Function

Serine Phosphorylation of SLP76 Is Dispensable for T Cell Development but Modulates Helper T Cell Function

... population of thymic or splenic cells shown in Fig 2 and S2 Fig are ...Bouchet and S Aguera (Lymphocyte Cell Biology Unit, Institut Pasteur) for critical reading the manuscript; ...

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en fr Role of OPA1 in striated muscle cell function and architecture and in response to stress Rôle d'OPA1 dans le fonctionnement et l'architecture des cellules musculaires striées et dans la réponse à un stress

... structure of Opa1 +/2 mitochon- dria, we performed detailed electron microscopic analysis of cardiac ...A and B, upper panel; and A, lower panel), the arrangement of mitochondria ...

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The role of ThPOK and T cell receptor signaling in CD4+ versus CD8+ T-cell lineage fate

The role of ThPOK and T cell receptor signaling in CD4+ versus CD8+ T-cell lineage fate

... presented in this thesis, we demonstrate that compared to MHC- I-restricted thymocytes, TCR signaling in MHC-II-restricted thymocytes is more potent in promoting ThPOK ...developmental and ...

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Role of EMMPRIN and MMPs in tooth development, dental caries and pulp-dentin regeneration

Role of EMMPRIN and MMPs in tooth development, dental caries and pulp-dentin regeneration

... M1 and M2 germs of new born mice. In the KO M2 germs, a cell polarization delay is observed in both pre-ameloblasts and pre-odontoblasts localized at the tip of the cusps ...

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Sustained correction of B-cell development and function in a murine model of X-linked agammaglobulinemia (XLA) using retroviral-mediated gene transfer

Sustained correction of B-cell development and function in a murine model of X-linked agammaglobulinemia (XLA) using retroviral-mediated gene transfer

... rescue in the BtkTec ⫺/⫺ model. First, the crucial role for Btk at the pre-B-cell transition most likely increased the relative survival and clonal expansion of Btk ⫹ pre-B ...Xid ...

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Loss of function mutations in KIF14 cause severe microcephaly and kidney development defects in humans and zebrafish

Loss of function mutations in KIF14 cause severe microcephaly and kidney development defects in humans and zebrafish

... agenesis and RHD with none of the mutations identified thus far affecting genes from these functional families (see (12, 50) for a recent list of CAKUT ...phenotypes in foetuses harbouring LOF ...

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CD4+ T Helper Cells Play a Key Role in Maintaining Diabetogenic CD8+ T Cell Function in the Pancreas

CD4+ T Helper Cells Play a Key Role in Maintaining Diabetogenic CD8+ T Cell Function in the Pancreas

... S1 in Supplementary ...field in (D), color-coded as function of ...T cell velocities (F) and arrest coefficients (g) (% time points spent at <3 µm/min for each track) ...

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Thymic neuroendocrine self-antigens. Role in T-cell development and central T-cell self-tolerance

Thymic neuroendocrine self-antigens. Role in T-cell development and central T-cell self-tolerance

... repertoire of thymic neuroendocrine precursors plays a dual role in T-cell differentiation as the source of either cryptocrine accessory sig- nals in T-cell ...

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Role of Cytokines in Thymus- Versus Peripherally Derived-Regulatory T Cell Differentiation and Function

Role of Cytokines in Thymus- Versus Peripherally Derived-Regulatory T Cell Differentiation and Function

... T cell pre- cursors under particular conditions of stimulation, present great similarities, and ...sion of the transcription factor Foxp3, widely recognized as the master regulator of ...

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The role of DcR3 in systemic lupus erythematosus and islet β-Cell viability and function

The role of DcR3 in systemic lupus erythematosus and islet β-Cell viability and function

... advent of a steroid-free immunosuppressive protocol in 2000 ...adoption of the Edmonton protocol, which uses steroid-free immunosuppression, has elevated the success of islet transplantation ...

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in vivo analysis of Drosophila deoxyribonucleoside kinase function in cell cycle, cell survival and anti-cancer drugs resistance.

in vivo analysis of Drosophila deoxyribonucleoside kinase function in cell cycle, cell survival and anti-cancer drugs resistance.

... dNK and its substrate dT (A) Diagram showing the percentage of viability of a WT strain on media containing a high concentration of AM (10mg/kg) or ...AM10 and display an extremely ...

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