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[PDF] Top 20 Revisiting the Training of Logic Models of Protein Signaling Networks with a Formal Approach based on Answer Set Programming

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Revisiting the Training of Logic Models of Protein Signaling Networks with a Formal Approach based on Answer Set Programming

Revisiting the Training of Logic Models of Protein Signaling Networks with a Formal Approach based on Answer Set Programming

... Abstract. A fundamental question in systems biology is the construc- tion and training to data of mathematical ...models. Logic formalisms have become very popular to model ... Voir le document complet

22

Reasoning on the response of logical signaling networks with answer set programming

Reasoning on the response of logical signaling networks with answer set programming

... in logic-based modeling In this thesis, we are interested in logic-based models, particularly Boolean networks and slight variations ...modeling approach is among ... Voir le document complet

155

Learning Boolean logic models of signaling networks with ASP

Learning Boolean logic models of signaling networks with ASP

... Boolean networks provide a simple yet powerful qualitative modeling approach in systems ...identification of logic rules underlying the system being studied is in most cases out ... Voir le document complet

29

Reasoning on the response of logical signaling networks with Answer Set Programming

Reasoning on the response of logical signaling networks with Answer Set Programming

... levels of causation pose indeed a long-term goal in the ...Logical signaling networks: state of the art and current challenges Among various discrete dynamical systems, ... Voir le document complet

47

Product robustness management : formalization by formal logic, application to set based design, and tolerancing

Product robustness management : formalization by formal logic, application to set based design, and tolerancing

... Examples The position of the point G can be determined by the resolution of the con- straints for i, however for finding the variation within the dwell, as well as ... Voir le document complet

274

Improved training of energy-based models

Improved training of energy-based models

... estimation of energy-based models is a challenging problem due to the intractability of the log-likelihood ...both the energy function and an amortized approximate ... Voir le document complet

62

CellNOptR: a flexible toolkit to train protein signaling networks to data using multiple logic formalisms

CellNOptR: a flexible toolkit to train protein signaling networks to data using multiple logic formalisms

... Douglas A Lauffenburger 2 and Julio Saez-Rodriguez 1* Abstract Background: Cells process signals using complex and dynamic ...in a context and cell type specific way is essential to understand ... Voir le document complet

15

The finiteness of logic programming derivations

The finiteness of logic programming derivations

... /be a pre­ interpretation of �, V a variable assignment with respect to J and A an ...is of the form p(tJ,···•' n J and that d 1 , ... , d n • elements of ... Voir le document complet

19

Towards a Set-based Signal Temporal Logic

Towards a Set-based Signal Temporal Logic

... Analysis of Dynamical Systems We consider continuous-time systems defined as the solution of initial value problem of ordinary differential equations (IVP-ODE) defined by ˙ y = f (y) ... Voir le document complet

9

Formal models for conformance test of programmable logic controllers

Formal models for conformance test of programmable logic controllers

... Construction of a test sequence when the specification is given in the form of a formal model with inputs and outputs, like a Mealy machine, has been ... Voir le document complet

25

A logic-based method to build signaling networks and propose experimental plans

A logic-based method to build signaling networks and propose experimental plans

... propose a logic-based method to automate the construction of signaling ...reproduce the reasoning made by biologists when interpreting experimental results, by ... Voir le document complet

12

Using Mutual Information and Answer Set Programming to refine PWM based transcription regulation network

Using Mutual Information and Answer Set Programming to refine PWM based transcription regulation network

... The first strategy for in silico network reconstruction uses the experimental sequences to extrapolate to other taxonomically related organisms ...using the binding site motif described in one ... Voir le document complet

9

Formal Synthesis of Real-Time System Models in a MDE Approach

Formal Synthesis of Real-Time System Models in a MDE Approach

... 2) With code generator: More specifically to RTES, Ptolemy project [11] is further adapted for describing ex- ecution ...models. The definition of those models relies on the ... Voir le document complet

15

Formal Derivation of Qualitative Dynamical Models from Biochemical Networks

Formal Derivation of Qualitative Dynamical Models from Biochemical Networks

... shows the behaviour of the qualitative model refined with a mass in- variant for the case study with a race between a unary and a binary reaction, ... Voir le document complet

101

An SMT-Based Approach to the Formal Analysis of MARTE/CCSL

An SMT-Based Approach to the Formal Analysis of MARTE/CCSL

... in the 𝕂 framework. 𝕂 is a rewrite-based executable semantic framework which is mainly used to formalize the operational semantics of programming languages, type systems and ... Voir le document complet

17

Formal Models for Programming and Composing Correct Distributed Systems

Formal Models for Programming and Composing Correct Distributed Systems

... One of the greatest contributions of this work is the formalisation of the ASP fun language, its semantics, and type system plus the proof of safety and progress in ... Voir le document complet

166

On constructing a logic for the notion of complete and immediate formal grounding

On constructing a logic for the notion of complete and immediate formal grounding

... step of a proof may be viewed as a basic inferential passage of a valid reasoning, the latter concerns an etiological conception of proofs and thus each step of ... Voir le document complet

27

Event-Based Control for Online Training of Neural Networks

Event-Based Control for Online Training of Neural Networks

... Online Training of Neural Networks Zilong Zhao 1 , Sophie Cerf 1 , Bogdan Robu 1 , and Nicolas Marchand 1 Abstract—Convolutional Neural Network (CNN) has become the most used method for image ... Voir le document complet

7

Formal certification of a compiler back-end, or: programming a compiler with a proof assistant

Formal certification of a compiler back-end, or: programming a compiler with a proof assistant

... equipped with a trivial type system hav- ing only two types: int and ...annotated with signatures sig giving the number and types of ar- guments, and an optional type for the ... Voir le document complet

14

Parameter-based reduction of Gaussian mixture models with a variational-Bayes approach

Parameter-based reduction of Gaussian mixture models with a variational-Bayes approach

... identifying the correct image given the query and the reduced ...95% of the 3 first ranked reduced models sets ...contain the correct ...[11] with 8 components per ... Voir le document complet

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