[PDF] Top 20 Retinoic Acid-Binding Protein in Human Breast Cancer and Dysplasia
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Retinoic Acid-Binding Protein in Human Breast Cancer and Dysplasia
... VOL. The pattern in text-figure IA was the one encountered in most tissue samples analyzed. Text- figure IB exhibits a profile typical of a biopsy sample with a [r] ... Voir le document complet
4
Tubulin binding cofactor C (TBCC) suppresses tumor growth and enhances chemosensitivity in human breast cancer cells.
... growth in vivo compared to MP6 ...cells in vitro was not reduced in com- parison to control cells and their volume was not altered (data not shown), we hypothesize that this reduced in ... Voir le document complet
15
Evolutionary diversification of retinoic acid receptor ligand-binding pocket structure by molecular tinkering
... RARs in general, the differences between RARα/RARβ and RARγ may reflect differences of evolutionary constraints acting on the RAR ...retinoid and although biological functions of oxidized ATRA ... Voir le document complet
16
Interleukin-22 binding protein (IL-22BP) is constitutively expressed by a subset of conventional dendritic cells and is strongly induced by retinoic acid
... transcripts in rat CD4 + spDCs (Figure 5), the longest and most intense one corresponding to the expected 678 bp mRNA, as further confirmed by ...putative protein of 229 AA (data not shown), showing ... Voir le document complet
28
Detection of Hoxa1 Expression in Human Breast Cancer
... genes in breast cancer cells, we have previously cloned three alternatively spliced HOXA1 transcripts from a MCF7 cDNA library and demonstrated that HOXA1 expression was modulated by ... Voir le document complet
6
An Unexpected Mode Of Binding Defines BMS948 as A Full Retinoic Acid Receptor β (RARβ, NR1B2) Selective Agonist
... Retinoic acid is an important regulator of cell differentiation which plays major roles in em- bryonic development and tissue ...of retinoic acid is mediat- ed by three nuclear ... Voir le document complet
21
Retinoic acid protects human breast cancer cells against etoposide-induced apoptosis by NF-kappaB-dependent but cIAP2-independent mechanisms.
... -475 and -130) and three NF-B binding sites (at positions -210, -197 and -147) in the proximal promoter of the cIAP2 gene have been predicted [31] but sequence analysis did not show ... Voir le document complet
17
Retinoic acid sensitivity of triple-negative breast cancer cells characterized by constitutive activation of the NOTCH1 pathway : the role of RARβ
... obtained in HCC-1599 and MB-157 cells exposed to ATRA, DAPT and ATRA+DAPT provide clues as to the gene networks and pathways participating in the NOTCH1-dependent anti-tumor action of ... Voir le document complet
23
The CCAAT/Enhancer-Binding Protein Beta-2 Isoform (CEBPbeta-2) Upregulates Galectin-7 Expression in Human Breast Cancer Cells
... amino acid sequences and affinity for b-galactose- containing oligosaccharides ...[1]. In mammals, the distribution of galectins is tissue-specific and their expression is developmentally ... Voir le document complet
8
Chronic oxidative stress promotes H2 AX protein degradation and enhances chemosensitivity in breast cancer patients
... H2AX in wt and junD-deficient fibroblasts (Fig 3D–G; Appendix Fig S2H) by taking advantage of epitope-tagged forms of H2AX, which have been previ- ously shown to behave and be regulated in the ... Voir le document complet
24
Differential Retinoic Acid Signaling in Tumors of Long- and Short-term Glioblastoma Survivors
... three retinoic acid signaling genes was statistically signifi- cantly increased in STS ...tumors. Retinoic acid signaling via cellular retinoic acid– binding ... Voir le document complet
4
The Tim-3-Galectin-9 Pathway and Its Regulatory Mechanisms in Human Breast Cancer
... for human breast cancer presented in The Cancer Genome ...increased in blood plasma of breast cancer patients, but not in AML patients, including those with ... Voir le document complet
13
SIRT1-dependent epigenetic regulation of H3 and H4 histone acetylation in human breast cancer
... Whole protein extracts from frozen tissues and cultured cells were obtained using T-PER™ Tissue Protein Extraction Reagent and RIPA buffer (ThermoFisher Scientific) respectively, containing ... Voir le document complet
19
Transactivation of vimentin by beta-catenin in human breast cancer cells
... Cytoplasmic and Nuclear Distribution of ...immunofluorescence in a set of eight human breast tumor cell lines (BT474, BT20, T47D, MCF- 7, MDA-MB-231, BT549, Hs578T, and ...vimentin, ... Voir le document complet
13
All-trans retinoic acid induces oxidative phosphorylation and mitochondria biogenesis in adipocytes
... Biochemistry and Molecular Biology, ...poor in mitochondria and have a low oxidative ...studies in both humans and rodents document- ing a negative association between mitochondrial ... Voir le document complet
11
Role of the microtubule-associated protein ATIP3 in cell migration and breast cancer metastasis
... Metastatic cancer cells were injected intracardiacally into the bloodstream of nude mice to reca- pitulate the late, rate-limiting, steps of the metastatic process, and examine metastatic dissemination to ... Voir le document complet
245
Effect of Inhibition of the Lysophosphatidic Acid Receptor 1 on Metastasis and Metastatic Dormancy in Breast Cancer
... dormancy in the 4T1 and MDA-MB-231T models ...p38 in metastatic lesions may result from the multitude of cytokines present in the liver and lungs, many of which are known to induce p38 ... Voir le document complet
14
Adipose Tissue Omega-3 and Omega-6 Fatty Acid Content and Breast Cancer in the EURAMIC Study
... The fatty acid content of adipose tissue in postmenopausal breast cancer cases and controls from five European countries in the European Community Multicenter Study on Antioxidants, Myoc[r] ... Voir le document complet
11
Lysyl oxidase-like 4 involvement in retinoic acid epithelial wound healing
... A and its active forms (retinoic acids/RAs) are known to have pro-healing properties, but their mechanisms of action are still poorly ...cellular and molecular processes by which atRA (all-trans RA) ... Voir le document complet
11
Manipulating protein acetylation in breast cancer: a promising approach in combination with hormonal therapies?
... activity in patients with solid tumor malignancies, thus prompting clinicians to use these compounds in combination with other therapies acting on other targets than ...HDACs and growth factor ... Voir le document complet
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