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[PDF] Top 20 Regulatory T cells in solid organ transplantation

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Regulatory T cells in solid organ transplantation

Regulatory T cells in solid organ transplantation

... therapeutics. Regulatory T (Treg) cells play an important role in modulating pro- inflammatory microenvironments and maintaining tissue ...These cells are a heterogeneous entity with ... Voir le document complet

16

B cells with regulatory properties in transplantation tolerance

B cells with regulatory properties in transplantation tolerance

... the regulatory B cells is the secretion of IL-10, which is one of the most potent anti-inflammatory cytokine to control ...IL-10 in suppression by B cells has been demonstrated only in ... Voir le document complet

15

Role of myeloid regulatory cells (MRCs) in maintaining tissue homeostasis and promoting tolerance in autoimmunity, inflammatory disease and transplantation

Role of myeloid regulatory cells (MRCs) in maintaining tissue homeostasis and promoting tolerance in autoimmunity, inflammatory disease and transplantation

... Myeloid cells play a key role in this process: they initiate effective and controlled immune responses that protect the ...myeloid cells with regulatory properties can protect the host from ... Voir le document complet

13

Regulatory B Cells and Tolerance in Transplantation: From Animal Models to Human

Regulatory B Cells and Tolerance in Transplantation: From Animal Models to Human

... al. Regulatory B cells and tolerance in transplantation by anti-CD45-RB therapy requires host B cells and that tolerance is mediated through the interaction of co-stimulatory molecules ... Voir le document complet

9

The use of mesenchymal stromal cells in solid organ transplantation

The use of mesenchymal stromal cells in solid organ transplantation

... of regulatory T cells (Tregs), DCs, and ...proliferation in vitro and to prolong skin graft survival in vivo ...MSCs in SOT is illustrated by the fact that donor-derived, autologous, ... Voir le document complet

11

Cell therapy using tolerogenic dendritic cells in transplantation

Cell therapy using tolerogenic dendritic cells in transplantation

... end. In fact, DC gener- ated with IL-10 added at the end of culture have an immature phenotype and display resistance to matur- ation stimuli ...anergy in CD4 + T cells [16] and CD8 + T cells ... Voir le document complet

9

Cell therapy using tolerogenic dendritic cells in transplantation.

Cell therapy using tolerogenic dendritic cells in transplantation.

... end. In fact, DC gener- ated with IL-10 added at the end of culture have an immature phenotype and display resistance to matur- ation stimuli ...anergy in CD4 + T cells [16] and CD8 + T cells ... Voir le document complet

9

Regulatory myeloid cells: an underexplored continent in B-cell lymphomas

Regulatory myeloid cells: an underexplored continent in B-cell lymphomas

... based in expression of receptors to the Fc portion of IgG isotype immunoglobulin (FcγRs), including high expression of CD32a/FcγRIIa ...roles in B-cell lymphomas, and the same might be expected to be ... Voir le document complet

26

Regulatory T cells fulfil their promise ?

Regulatory T cells fulfil their promise ?

... resulting in haploidentical ...situation, in which the delicate balance between immu- nity and tolerance has yet to be ...T cells are included in the donor graft, graft-versus-host disease ... Voir le document complet

2

CD4(+)CD25(+) regulatory T lymphocytes in bone marrow transplantation.

CD4(+)CD25(+) regulatory T lymphocytes in bone marrow transplantation.

... involved in protection from GvHD by regulatory T cells? The observation that Treg expressing high (but not low) levels CD62L efficiently inhibit GvHD lethality indicates that initially they primarily ... Voir le document complet

17

Topography of cancer-associated immune cells in human solid tumors.

Topography of cancer-associated immune cells in human solid tumors.

... CD163 in the tumor core and the outer invasive margin were not significantly correlated to overall survival (hazard ratios [HR] for death from any cause were ...types in both compartments, Supplementary ... Voir le document complet

19

Allogeneic hematopoietic stem cell transplantation in solid organ transplant recipients: a retrospective, multicenter study of the EBMT

Allogeneic hematopoietic stem cell transplantation in solid organ transplant recipients: a retrospective, multicenter study of the EBMT

... retransplantation in one) and one recipient of a liver graft underwent a second liver ...a solid organ graft without immune ...suppressing regulatory T cell function. Whereas the majority of ... Voir le document complet

10

Reply to “Biologics in organ transplantation”

Reply to “Biologics in organ transplantation”

... ASKP1240 in nonhuman primates. Am J Transplant 2012; 12: 1740. 3. Poirier N, Azimzadeh AM, Zhang T, et al. Inducing CTLA-4- dependent immune regulation by selective CD28 blockade promotes regulatory T ... Voir le document complet

2

Rationale for the potential use of mesenchymal stromal cells in liver transplantation.

Rationale for the potential use of mesenchymal stromal cells in liver transplantation.

... data in clinic show that MSCs are safe to use, at least in the medium-term, but more time is needed to evaluate their potential adverse effects on the ...use in vitro and in vivo (animals and ... Voir le document complet

15

Regulatory B cells in myasthenia gravis are differentially affected by therapies

Regulatory B cells in myasthenia gravis are differentially affected by therapies

... Methods Blood and thymic samples For blood samples, patients had an early-onset form of MG (no thymoma) with anti-AChR antibodies. Patients for glo- bal analyses (Figs. 1, 2F) were not thymectomized (n = 25; 11–38 years ... Voir le document complet

8

Molecular Signatures of Human Regulatory T Cells in Colorectal Cancer and Polyps

Molecular Signatures of Human Regulatory T Cells in Colorectal Cancer and Polyps

... cases in 2012 ( 19 ). In Malaysia, 2,246 CRC cases ...reported in 2011 ( 20 ...roles in the pathogenesis of ...hallmark in cancer progression ( 21 ...role in tumorigenesis ( 22 – ... Voir le document complet

9

Calculations of transport phenomena in solid-oxide fuel cells

Calculations of transport phenomena in solid-oxide fuel cells

... fuel cells are normally operated in stacks separated by ...the cells are in parallel, with fuel and oxidant being supplied and removed via ...is in some ways similar to a single-pass ... Voir le document complet

9

Role of regulatory T cells in the pathogenesis of HIV-1 infection

Role of regulatory T cells in the pathogenesis of HIV-1 infection

... which, in combination with the progressive depletion of CD4 T cells, profoundly perturbs antigen-specific CD8 T cell ...FoxP3+ regulatory T cells (Treg) ... Voir le document complet

2

Alloantigenic recognition properties of CD8+ regulatory T cells

Alloantigenic recognition properties of CD8+ regulatory T cells

... Published: 23 November 2011 References 1. Guillonneau C, Hill M, Hubert FX, Chiffoleau E, Herve C, Li XL, Heslan M, Usal C, Tesson L, Menoret S, et al: CD40Ig treatment results in allograft acceptance mediated by ... Voir le document complet

2

Deciphering the Crosstalk Between Myeloid-Derived Suppressor Cells and Regulatory T Cells in Pancreatic Ductal Adenocarcinoma

Deciphering the Crosstalk Between Myeloid-Derived Suppressor Cells and Regulatory T Cells in Pancreatic Ductal Adenocarcinoma

... depletion in a mouse model of PDAC shapes the functional differentiation of ...development in a cell-cell dependent ...Treg cells affect the survival and/or the proliferation of MDSCs in ... Voir le document complet

17

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