[PDF] Top 20 Regulatory role of natural killer T cells in diabetes
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Regulatory role of natural killer T cells in diabetes
... 2 diabetes are growing public health ...defects in immune regulation. Invariant natural killer T (iNKT) cells are innate-like T cells that recognize glycolipids presented by ... Voir le document complet
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Dissection of the role of natural killer cells in atherosclerosis using selective genetic approaches
... 80 Quantitative real-time PCR Total ribonucleic acid (RNA) from spleen or abdominal aorta was extracted using Trizol reagent (Invitrogen). Quantitative real-time polymerase chain reaction (PCR) was performed on an ABI ... Voir le document complet
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Invariant natural killer T cells and TGF-ß attenuate anti-GBM glomerulonephritis
... Invariant natural killer T (iNKT) cells represent a particular subset of T lymphocytes capable of producing several cytokines, which exert regulatory or effector functions, ... Voir le document complet
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Fine characterization of intrahepatic NK cells expressing natural killer receptors in chronic hepatitis B and C.: NK cells in chronic hepatitis C and hepatitis B
... evade natural killer (NK) cell effector functions illustrate the central role for these cells in early host defense against viral infections [2, ...activation of Interferon ... Voir le document complet
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Dengue Virus-Infected Dendritic Cells, but Not Monocytes, Activate Natural Killer Cells through a Contact-Dependent Mechanism Involving Adhesion Molecules
... Department of Biology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA f ABSTRACT Natural killer (NK) cells play a protective role against dengue virus ... Voir le document complet
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ITGBL1 is a new immunomodulator that favors development of melanoma tumors by inhibiting natural killer cells cytotoxicity
... Melanoma cells were transfected with siRNA control or 2 different siRNA directed against ...to cells and acquisition using Incucyte was performed. Quantification of melanoma cells death is ... Voir le document complet
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Regulatory T cells in solid organ transplantation
... Trials in progress In contrast to the study above, other transplant centres have focussed on manufacturing a ‘purer’ Treg cell product with/without alloantigen specificity instead (See Table ...line ... Voir le document complet
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Increased Degranulation of Natural Killer Cells during Acute HCV Correlates with the Magnitude of Virus-specific T cell Responses
... evolution of the NK cells phenotype and function during acute HCV infections in a unique cohort of IDUs with either spontaneous resolution or chronic ...activity in a cohort of ... Voir le document complet
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Natural Killer Cells and Pre-B Acute Lymphoblastic Leukemia : Evidence for an Unconventional Cytotoxicity Pathway
... NK cells, with a strong enrichment for phagocytosis, endocytosis, receptor-mediated endocytosis and Fc receptor signaling related gene ontology terms (Figure ...NK cells in the semng of a ... Voir le document complet
147
Longitudinal Analysis of Natural Killer Cells in Dengue Virus-Infected Patients in Comparison to Chikungunya and Chikungunya/Dengue Virus-Infected Patients
... analysis of a panel of phenotypic markers of the NK cell subset only strengthened the evidence of NKR repertoire modulation, showing that CHIKV- and DENV-2-infected patients develop different ... Voir le document complet
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en fr Neuroblastoma and gastrointestinal stromal tumor as a target for natural killer lymphocytes : the role of ncr3/nkp30 Activité anti-tumorale des lymphocytes natural killer dans le neuroblastome et la tumeur gastrointestinal : le rôle de ncr3/nkp30
... characterization of NK cells. N.D. and K.C. participated to the study of the NKp30 isoforms ...study of the expression of ...part of the replication of the genetic ... Voir le document complet
114
Delineation of Natural Killer Cell Differentiation from Myeloid Progenitors in Human
... NK cells do not express CD56 and some activation and inhibitory receptors such as NKp30, NKp44, and ...NK cells also differ significantly in signal transduction and activation 13 ...study of ... Voir le document complet
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IL-2 reverses established type 1 diabetes in NOD mice by a local effect on pancreatic regulatory T cells
... course of low-dose IL-2 administration at diabetes onset can reverse established disease in NOD ...cient in the absence of naturally occurring T reg ...activity in the ...tested ... Voir le document complet
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Transient Complement Inhibition Promotes a Tumor-Specific Immune Response through the Implication of Natural Killer Cells
... inhibition of complement increased NK cell numbers in spleen and tumor leading to the.. 68.[r] ... Voir le document complet
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Rencontre avec un pathogène : les cellules natural killer se souviennent-elles ?
... stimulation in vitro par le récepteur ...persistent in situ pourraient être sensibilisées avec une certaine spé- cificité chez des souris déficientes en cellules T et ... Voir le document complet
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High mTOR activity is a hallmark of reactive natural killer cells and amplifies early signaling through activating receptors
... +SD) of IFN-g or CD107a positive cells among splenic NK cells from C57BL/6 or B2m / mice following 4 hr stimulation with coated ...anti-NKp46 in the presence or absence of 200UI/ml IL-2 ... Voir le document complet
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Les cellules natural killer : des cibles prometteuses dans la thérapie contre le cancer
... 8. Gauthier L, Morel A, Anceriz N, et al. Multifunctional natural killer cell engagers targeting NKp46 trigger protective tumor immunity. Cell 2019 ; 177 : 1701-13 n’induit pas d’attaque du greffon contre ... Voir le document complet
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B7-H6 : un nouveau signal d’alarme pour les cellules natural killer
... Récepteurs activateurs et inhibiteurs des cellules NK Les mécanismes moléculaires permet- tant aux cellules NK de distinguer une cellule stressée d’une cellule saine repo- sent sur un ensemble de récepteurs acti- vateurs ... Voir le document complet
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Natural Killer Cell Sensing of Infected Cells Compensates for MyD88 Deficiency but Not IFN-I Activity in Resistance to Mouse Cytomegalovirus
... Impact of MyD88 and Ly49H deficiencies on antiviral CD8 T cell responses and spleen ...(A) In vivo cytotoxic activity of antiviral CD8 T cells at d6 post-infection in BALB/c-Ly49H + , ... Voir le document complet
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Les cellules natural killer - Adaptation et mémoire dans le système immunitaire inné
... Le rôle des récepteurs inhibiteurs dans la calibration de la réactivité NK Les cellules NK expriment des récepteurs inhibiteurs qui reconnaissent les molécules du CMH-I. Cette reconnaissance contribue à déterminer le ... Voir le document complet
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