Top PDF Regulation of the Early Growth Response Protein-1 in vascular smooth muscle cells
Regulation of the Early Growth Response Protein-1 in vascular smooth muscle cells
... ATIONALE OF E GR -1 DOWNREGULATION AND POTENTIAL OF TARGETING STIM-1 AND O RAI -1 The major hallmark of atherosclerotic disease or restenosis following angioplasty is ...
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The activation function-1 of estrogen receptor alpha prevents arterial neointima development through a direct effect on smooth muscle cells
... on vascular media area in injured carotids were found to be similar to those in control ...with the results obtained in the present study, which suggests that the ...
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Early growth response protein 1 (Egr-1) expression by Insulin-like growth factor 1 (IGF-1) involves MAPKs and PKB pathways
... and regulation Igf-1 gene consists of 6 exons and 5 ...primarily in the liver and its plasma concentration is regulated by liver GH; however the ability of GH to stimulate ...
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Systemic sclerosis immunoglobulin induces growth and a pro-fibrotic state in vascular smooth muscle cells through the epidermal growth factor receptor
... ongoing in order to elucidate the exact role of TLRs and other PRRs in ...onset in response to a pathogen or trauma and a short duration, in the order of ...
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Natriuretic peptide receptor-C activation regulates vascular smooth muscle cell hypertrophy : molecular mechanisms
... Mitogen-activated protein kinases (MAPKs) are a highly conserved family of serine/threonine proteins which are activated by mitogenic ...kinase 1 and 2 (ERK1/2) with isoform p42 and p44, c-Jun ...
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Endothelin-1 and H2O2-induced signaling in vascular smooth muscle cells : modulation by CaMKII and Nitric oxide
... involved in cellular growth and proliferation two important phenomenons by which ET-1 triggers some of pathophysiological ...states. In parallel, it is also known that ET-1 ...
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Biochemical Properties of Gastrokine-1 Purified from Chicken Gizzard Smooth Muscle.
... strengthening of gastrokine-1 and actin interaction. With the aim of determining the potential involvement of gastrokine-1 in the regulation of ...
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The Effect of Resveratrol on the Hyperproliferation of Vascular Smooth Muscle Cells from Spontaneously Hypertensive Rats : Molecular Mechanisms
... ABSTRACT Vascular remodeling due to the hyperproliferation and hypertrophy of vascular smooth muscle cells (VSMCs) is central in the development of ...
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Hydrogen peroxide enhances the expression and function of Giα proteins in aortic vascular smooth muscle cells from Sprague-Dawley rats : role of growth factor receptors transactivation
... Activation of platelet-derived growth factor receptor Platelet-derived growth factor receptors (PDGFR) are membrane protein-tyrosine kinases that play an important role in the ...
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PKB mediates Insulin-Like Growth Factor 1-induced phosphorylation and nuclear export of Histone Deacetylase 5 via NADPH Oxidase 4 activation in vascular smooth muscle cells
... The main feature of CVD is an increased vascular resistance due to blood vessel remodeling ...specialized cells that regulate vascular tone and blood pressure ...migration, ...
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Modulation of Endothelin-1 and Insulin-like Growth Factor Type 1-induced Signaling by Curcumin in A-10 Vascular Smooth Muscle Cells
... highlighting the requirement for improved ...activation of ET-1-induced signaling in vascular smooth muscle cell (VSMC), including protein kinase B (PKB) and ...
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Cysteinyl leukotriene signaling through perinuclear CysLT(1) receptors on vascular smooth muscle cells transduces nuclear calcium signaling and alterations of gene expression.
... members of the serine proteinase inhibitor family and act as important inhibitors of fibrinolysis by inter- fering with the plasminogen ...stimuli in vascular SMCs and may ...
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Redox regulation of ET-1-induced activation of ERK1/2, PKB and Pyk2 signaling in A-10 vascular smooth muscle cells
... Calcium-dependent epidermal growth factor receptor transactivation mediates the angiotensin II induced mitogen-activated protein kinase activation in vascular smooth muscle ceils. Yamagu[r] ...
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Smooth muscle cell specific deletion of the PKGIα target RGS2 induces vascular dysfunction and hypertension
... age of 7 ...(DSI) of blood pressure (BP) and heart rate (HR) in male RGS2- SMC-KO mice showed that these mice have a significant increase in systolic BP ...change in HR. The ...
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New Fibrous PET Structures for Vascular Grafts: Effect of Fiber Structure on Endothelial and Smooth Muscle Cell Attachment and Growth
... assessed the ability of human brain endothelial cells (HBEC) and human aortic smooth muscle cells (AoSMC) to attach and proliferate on five different discoidal materials ...
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Role of vascular plasticity in muscle remodeling in the child
... events of necrosis-inflammation, they differ regarding ...cause the capillary necrosis which results in focal capillary loss, perivascular inflammation, and muscle ischemia ...70% of ...
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Regulation of the unfolded protein response by noncoding RNA
... CDKN1A protein levels (25) miR-424(322)-503 cluster Down ATF6 HEK 293T/H9c2/MEFs Decrease in ATF6 mRNA, enhanced RIDD activity (37) miR-452-5p Down CDKN1B HeLa/HEK293 Decreased CDKN1B protein levels ...
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Regulation of tumor-stroma interactions by the unfolded protein response
... remarks The UPR signaling has a broad impact on cancer ...tumor cells with the selective advantages to survive and propagate in harsh environmental conditions, but also educates the ...
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Therapeutic vascular growth in the heart
... Therapeutic vascular growth in the heart 1:1 H12 Cell therapies and exosomes In parallel to these advances in angiogenic gene and protein therapies, cell ...
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An image analysis method to survey the dynamics of polar protein abundance in the regulation of tip growth
... designs of Cdc42-based polarity machineries allows cells to grow from one or multiple sites sharing the same cytoplasm (Das et ...typical in fission yeast during NETO, as well as in ...
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