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[PDF] Top 20 Regulation of human adipose tissue gene expression in relation to obesity and insulin resistance

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Regulation of human adipose tissue gene expression in relation to obesity and insulin resistance

Regulation of human adipose tissue gene expression in relation to obesity and insulin resistance

... potential to reduce fat mass, while it does not affect the muscle mass and ...effect of resistance training in skeletal muscle, we can also assume that muscle may communicate with AT ... Voir le document complet

214

Regulation of lipogenesis in human adipose tissue: effect of metabolic stress, dietary intervention and aging

Regulation of lipogenesis in human adipose tissue: effect of metabolic stress, dietary intervention and aging

... found in our previous clinical study performed on obese women [349] was not achieved in this ...degree of weight loss and overall length of the intervention. In the previous ... Voir le document complet

160

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en fr Adipose Tissue Basement Membrane : its remodeling during obesity and its relationship with insulin-resistance La Membrane Basale du Tissu adipeux : son remodelage au cours de l'obésité et sa relation avec l'insulino-résistance

... 13! In many tissues such as kidney or retina, BM remodeling is related to insulin resistance and a hyperglycemic ...fibrosis in AT is associated with deterioration of ... Voir le document complet

244

Adaptive Expression of MicroRNA-125a in Adipose Tissue in Response to Obesity in Mice and Men

Adaptive Expression of MicroRNA-125a in Adipose Tissue in Response to Obesity in Mice and Men

... mediators in the regulation of adipose tissue biology and the development of ...role of microRNA-125a has been suggested in the pathogenesis of ... Voir le document complet

14

Altered skeletal muscle lipase expression and activity contribute to insulin resistance in humans.

Altered skeletal muscle lipase expression and activity contribute to insulin resistance in humans.

... muscle insulin resistance is a strong risk factor of type 2 diabetes and cardiovascular dis- eases ...Dysfunctional adipose tissue can lead to lipid oversupply and ... Voir le document complet

10

Apelin and APJ regulation in adipose tissue and skeletal muscle of type 2 diabetic mice and humans.

Apelin and APJ regulation in adipose tissue and skeletal muscle of type 2 diabetic mice and humans.

... by insulin, is increased in adipose tissue (AT) and plasma with ...player in the control of glucose homeostasis. However, the regulation of apelin and ... Voir le document complet

10

Immune cell-derived cytokines contribute to obesity-related inflammation, fibrogenesis and metabolic deregulation in human adipose tissue

Immune cell-derived cytokines contribute to obesity-related inflammation, fibrogenesis and metabolic deregulation in human adipose tissue

... 1,2,3 Adipose tissue contains a variety of immune cells, which vary in abundance and phenotype with ...contribution of immune cell-derived factors to inflammatory, ... Voir le document complet

12

Mapping of the fibroblast growth factors in human white adipose tissue.

Mapping of the fibroblast growth factors in human white adipose tissue.

... Department of Biosciences and Nutrition ...Institutet, and Clinical Research Centre ...Department of Medicine at Karolinska Institutet and Karolinska University Hospital ...Department ... Voir le document complet

6

Characterization of tissue-specific differential DNA methylation suggests distinct modes of positive and negative gene expression regulation

Characterization of tissue-specific differential DNA methylation suggests distinct modes of positive and negative gene expression regulation

... methylation in gene bodies correlates with tran- scriptional activity [7], our observation is novel, and dif- ferent to the previous ...CHG and CHH methylation) within gene body ... Voir le document complet

12

The importance of gene–environment interactions in human obesity

The importance of gene–environment interactions in human obesity

... investigation of socio-economic factors and lifestyle behaviours has revealed many additional conditions that impact heritability ...emergence of a society characterized by food abundance and ... Voir le document complet

52

The Frequencies of Immunosuppressive Cells in Adipose Tissue Differ in Human, Non-human Primate, and Mouse Models

The Frequencies of Immunosuppressive Cells in Adipose Tissue Differ in Human, Non-human Primate, and Mouse Models

... NHPs and humans. Our results highlighted a number of differences in the AT between the various ...composition of the stromal vascular fraction of adipose tissue, we first ... Voir le document complet

15

Relationships between glycaemic abnormalities, obesity and insulin resistance in nondiabetic Polynesians of New Caledonia.

Relationships between glycaemic abnormalities, obesity and insulin resistance in nondiabetic Polynesians of New Caledonia.

... shown to apply to many populations around the world ...between insulin resistance and deficient insulin secretion in the pathogenesis of type 2 diabetes appears ... Voir le document complet

18

New CT imaging method for adipose tissue analysis in mouse model of obesity

New CT imaging method for adipose tissue analysis in mouse model of obesity

... deposit and dissemination of sci- entific research documents, whether they are pub- lished or ...teaching and research institutions in France or abroad, or from public or private research ... Voir le document complet

2

MR (Mineralocorticoid Receptor) Induces Adipose Tissue Senescence and Mitochondrial Dysfunction Leading to Vascular Dysfunction in Obesity

MR (Mineralocorticoid Receptor) Induces Adipose Tissue Senescence and Mitochondrial Dysfunction Leading to Vascular Dysfunction in Obesity

... 7. Tchkonia T, Morbeck DE, Von Zglinicki T, Van Deursen J, Lustgarten J, Scrable H, Khosla S, Jensen MD, Kirkland JL. Fat tissue, aging, and cellular senescence. Aging Cell. 2010; 9:667-684. doi: ... Voir le document complet

30

Adipose tissue fibrosis assessed by high resolution ex vivo MRI as a hallmark of tissue alteration in morbid obesity

Adipose tissue fibrosis assessed by high resolution ex vivo MRI as a hallmark of tissue alteration in morbid obesity

... number of excitations =8, bandwidth =592 Hz per pixel, matrix: 128×128, spatial resolution (µm) ...Single-slice and total (over three contiguous slices) fibrosis fractions were measured from T1 maps ... Voir le document complet

8

Statin therapy modulates thickness and inflammatory profile of human epicardial adipose tissue

Statin therapy modulates thickness and inflammatory profile of human epicardial adipose tissue

... thickness and in flammatory profile in patients with AS. In particular, our results indicate that the statin related EAT anti-in flammatory effect is the result of a direct action ... Voir le document complet

5

The spatial landscape of gene expression isoforms in tissue sections

The spatial landscape of gene expression isoforms in tissue sections

... total of 100,838 A-to-I RNA editing sites described in the literature ...[11,12]. To reach high confidence calls with long-read data, we defined ad hoc thresholds for the number of ... Voir le document complet

12

Gene regulation and chromatin organization: relevance of cohesin mutations to human disease

Gene regulation and chromatin organization: relevance of cohesin mutations to human disease

... promoter and enhancer mostly occurs in a tissue‐specific fashion, although interactions between promoters and distal regions can also be conserved between tissues, the tissue‐specific ... Voir le document complet

20

Cannabinoid CB2 receptor potentiates obesity-associated inflammation, insulin resistance and hepatic steatosis.

Cannabinoid CB2 receptor potentiates obesity-associated inflammation, insulin resistance and hepatic steatosis.

... resistance and NAFLD ...during obesity progression, Cnr2 expression undergoes a strong increase in adipose tissue parallel to the development of fat ... Voir le document complet

13

Regulation of gene expression in the dinoflagellate Lingulodinium polyedrum

Regulation of gene expression in the dinoflagellate Lingulodinium polyedrum

... Splicing and the spliceosome Several posttranscriptional modifications in the primary transcripts of eukaryotic cells are necessary to create a mature mRNA that can be efficiently translated, ... Voir le document complet

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