[PDF] Top 20 Role of receptor and non-receptor protein tyrosine kinases in vasoactive peptide-induced signaling
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Role of receptor and non-receptor protein tyrosine kinases in vasoactive peptide-induced signaling
... effects of prolonged hypertension. Based on such studies and others, the new JNC definitions have made it easier to diagnose hypertension and the increased blood pressure conditions which precede ... Voir le document complet
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The role of small adaptor proteins in the control of oncogenic signaling driven by tyrosine kinases in human cancer
... regulAtIon of tK sIgnAlIng by smAll AdAptors In non-trAnsformed cells Adaptor proteins define an important class of “readers” in the transmission of pTyr-dependent ... Voir le document complet
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The non-receptor tyrosine kinase Pyk2 modulates acute locomotor effects of cocaine in D1 receptor-expressing neurons of the nucleus accumbens
... the role of D1 receptor- expressing neurons is established, underlying molecular pathways are not fully ...the role of Pyk2, a non-receptor, calcium-dependent ... Voir le document complet
17
Role of ErbB/HER family of receptor tyrosine kinases in cholangiocyte biology
... and increased expression of EGFR and tumor necrosis factor a ...(26) In vitro, EGF or TGFa, com- bined with TNFa, induced an overexpression of EGFR resulting in MUC5AC ... Voir le document complet
29
Regulation of hormone signaling by nuclear receptor interacting proteins.
... complexity of the regulatory mechanisms that control nuclear receptor expression and ...involved in transcriptional repression and post-translational modifications might be key ... Voir le document complet
18
Inhibition of neuronal FLT3 receptor tyrosine kinase alleviates peripheral neuropathic pain in mice
... site of the FLT3 kinase domain have been developed and are currently under clinical evaluation for the treatment of FLT3- mutated acute myeloid leukemia 44 , 45 ...potent and selective FLT3 ... Voir le document complet
14
NRIP1 (nuclear receptor interacting protein 1)
... methylation of nuclear co-repressor receptor interacting protein 140 J Proteome Res 2009 Mar;8(3):1156-67 Izzo A, Manco R, Bonfiglio F, Cal G, De Cristofaro T, Patergnani S, Cicatiello R, Scrima R, ... Voir le document complet
6
Phosphorylation Of Histone Deacetylase 7 By Protein Kinase D Mediates T Cell Receptor-Induced Nur77 Expression And Apoptosis
... promoter and locus control region to express a membrane- or cytosol-targeted active PKD in transgenic mice T cells ...Expression of active PKD in the cytosol had a dramatic effect on thymocyte ... Voir le document complet
12
Endothelial cell protein C receptor and the risk of venous thrombosis.
... anticoagulant protein C (PC) pathway plays a major role in regulating coagulation and inflammation (reviews ...activator of PC. In the presence of its cofactor ... Voir le document complet
13
Distinct patterns of B-cell receptor signaling in non-Hodgkin lymphomas identified by single-cell profiling.
... 21 of 23 NF-ĸB in CLL and MCL cells, shown relative to unstimulated ...activation-induced signaling profiles shown as heatmaps of lymphoma cells from CLL and MCL patient ... Voir le document complet
31
A G protein–coupled receptor mediates neuropeptide-induced oocyte maturation in the jellyfish Clytia
... receptors of the core hypothalamus-pituitary-gonadal GPCRs, but rather forms a superfamily with receptors of these “upstream” neuropeptide hormones, notably GnIH, QRFP, Neuropeptide Y, and ... Voir le document complet
26
Leucine-Rich Repeat Receptor Kinases are sporadically distributed in eukaryotic genomes
... Conclusions In conclusion, we have shown that the Monosiga, Chlor- ella, Ectocarpus and oomycete LRR-RK receptors belong to the RKG and are likely to have acquired the LRRs in their ECDs ... Voir le document complet
10
The Role of Aryl Hydrocarbon Receptor (AHR) and AHR-Interacting Protein (AIP) in the Pathogenesis of Pituitary Adenomas
... a non- ligand endogenous activator of AhR, able to stimulate its translocation to the nucleus simi- larly to dioxin, although in this case nuclear AhR does not appear to dimerize with ARNT or induce ... Voir le document complet
13
A G-protein-coupled receptor mediates neuropeptide-induced oocyte maturation in the jellyfish Clytia
... Phenotypes of Clytia MIHR mutants Light and confocal microscope images of MIHR mutant F0 polyp colonies and ...Morphology of a wild type (WT) colony (Z11, top) and a MIHR mutant ... Voir le document complet
39
Purification and Identification of G Protein- coupled Receptor Protein Complexes under Native Conditions
... with in- creasing detergent concentrations at 4 °C (a) or for the indicated times in the presence of ...measured in the soluble and insoluble fraction to determine the percentage ... Voir le document complet
11
The role of the nuclear receptor Nr5a2 in ovulation in mice
... distribution and protein expression of Cx43 on Amhr2Cre-cKO and Amhr2Cre- control ovaries at 0 h and 12 h (n=3/time point/genotype) after hCG injection was verified by fluorescence ... Voir le document complet
86
Role of the androgen receptor in the central nervous system
... mood and cognitive ...prenatal and postnatal surges of gonadal testosterone, and continues through puberty and even ...adulthood. In the nervous system, the effects of ... Voir le document complet
43
Bile acids alter male fertility through G-protein-coupled bile acid receptor 1 signaling pathways in mice
... 1,2,3,4 and David H. Volle 1,2,3,4 Bile acids (BAs) are signaling molecules that are involved in many physiological functions, such as glucose and energy ...activation of the nuclear ... Voir le document complet
12
A role for peroxisome proliferator-activated receptor gamma in resveratrol-induced colon cancer cell apoptosis.
... prevention of tumor development is more relevant than treating established ...Avoidance of risk behaviors remains the most efficient approach for cancer prevention, but the development of active ... Voir le document complet
34
Structure and dynamics of G protein-coupled receptor–bound ghrelin reveal the critical role of the octanoyl chain
... NMR and CG modeling data with nonacylated ghrelin highlight the paramount role of the octanoyl chain in ghrelin structure and binding to ...folding of the ghrelin hydrophobic ... Voir le document complet
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