[PDF] Top 20 CD81-receptor associations-impact for hepatitis C virus entry and antiviral therapies
Has 10000 "CD81-receptor associations-impact for hepatitis C virus entry and antiviral therapies" found on our website. Below are the top 20 most common "CD81-receptor associations-impact for hepatitis C virus entry and antiviral therapies".
CD81-receptor associations-impact for hepatitis C virus entry and antiviral therapies
... binding and subsequent downstream events described above, CD81 has also been shown to contribute to HCV entry by forming a co-receptor complex through its interaction with other ...the ... Voir le document complet
19
Characterization of hepatitis C virus particle subpopulations reveals multiple usage of the scavenger receptor BI for entry steps
... (27–29) and in vitro using HCV models (12, 13, 30 –34) suggest that viral entry into hepatocytes, the predominant tar- get cells, is a complex process involving the viral E1 and E2 envelope ... Voir le document complet
27
Hepatitis C virus entry: molecular mechanisms and targets for antiviral therapy.
... as CD81-HCV interaction (38). 3.2.2.3. LDL receptor The LDL receptor (LDLR) transports cholesterol-containing lipoproteins into the cell by endocytosis via clathrin-coated ...pits. ... Voir le document complet
17
EGFR and EphA2 are host factors for hepatitis C virus entry and possible targets for antiviral therapy.
... cells and (e) HCVpp entry into PHH after inhibition of binding and postbinding steps by the indicated compounds (EGFR-specific mAbs: 10 and 50 µg mL –1 ) (f,g) Effect of Erlotinib and ... Voir le document complet
32
Hepatitis C Virus (HCV)-Apolipoprotein Interactions and Immune Evasion and Their Impact on HCV Vaccine Design
... infected, hepatitis C virus (HCV) is one of the leading causes of liver disease and hepatocellular ...efficient antiviral therapies have entered clinical standard of care, the ... Voir le document complet
10
A novel monoclonal anti-CD81 antibody produced by genetic immunization efficiently inhibits Hepatitis C virus cell-cell transmission.
... relevant for the development of novel antiviral antibodies for prevention and treatment of HCV ...infection. CD81 may be an attractive therapeutic target for the development of ... Voir le document complet
12
Cholesterol uptake and hepatitis C virus entry.
... alpha and ribavirin has markedly improved the treatment outcome, viral resistance and adverse effects still remain important ...HCV entry is the first step of virus- hepatocyte interaction ... Voir le document complet
9
Association between disruption of CD4 receptor dimerization and increased human immunodeficiency virus type 1 entry
... viral entry efficiency, we generated stable cell lines by transfecting A201, a human CD4 negative T cell line [14], with expression vectors encoding CD4-WT or the dimeri- zation ...sorting and then ... Voir le document complet
8
Ultradeep Pyrosequencing and Molecular Modeling Identify Key Structural Features of Hepatitis B Virus RNase H, a Putative Target for Antiviral Intervention.
... against hepatitis B virus (HBV) and have a high barrier to resis- ...possible, and cure of infection cannot be achieved with these therapies, emphasizing the need for alternative ... Voir le document complet
11
Mutations that alter use of hepatitis C virus cell entry factors mediate escape from neutralizing antibodies.
... host-cell entry factors as a mechanism by which HCV evades host immune ...the CD81 receptor also allowed the virus to escape neutralizing ...affect virus-antibody interactions during ... Voir le document complet
59
Effet antiviral des interférons sur le virus BK
... D’autres études ont souligné un rôle de IDO dans la persistance et/ou la progression de certaines infections virales en raison de ses propriétés immunomodulatrices [118]. En participant à la tolérance immunitaire ... Voir le document complet
74
Hepatitis C virus, cholesterol and lipoproteins--impact for the viral life cycle and pathogenesis of liver disease.
... expression and sulfation level plays a critical role in hepatocyte uptake of TRL ...accessibility and exposure to the circulatory ...encounter and interact with highly sulfated, negatively charged ... Voir le document complet
34
Genotype 1 hepatitis C virus envelope features that determine antiviral response assessed through optimal covariance networks
... combined antiviral therapy of pegylated alfa-interferon and ribavarin for hepatitis C virus (HCV) infection may be linked to mutations in the viral envelope gene E1E2 (env), which can ... Voir le document complet
10
Direct-acting Antiviral Therapy Restores Immune Tolerance to Patients With Hepatitis C Virus-induced Cryoglobulinemia Vasculitis
... study and received interferon-free DAA therapy. All were positive for HCV ...study, and presented with active HCV vasculitis defined by clinically active vasculitis with skin, joint, renal, ... Voir le document complet
29
Hepatitis C virus-related vasculitis
... laboratory and during centrifugation to avoid premature precipitation ; ii) serum samples must be stored at 4°C for one week to ensure the detection of delayed cryoprecipitation ; iii) immunoelectrophoresis ... Voir le document complet
19
Functional analysis of claudin-6 and claudin-9 as entry factors for hepatitis C virus infection of human hepatocytes using monoclonal antibodies.
... archive for the deposit and dissemination of sci- entific research documents, whether they are pub- lished or ...teaching and research institutions in France or abroad, or from public or private ... Voir le document complet
18
Prevalence of hepatitis E virus and reassessment of HIV and other hepatitis virus seroprevalences among French prison inmates
... 10.5% for age group 18–27 and 14% for age group 28–37 ...lifestyle and diet, and possibly religious beliefs. Unfortunately, for ethical reasons, this information was not ... Voir le document complet
11
Un double effet antiviral des IFITM sur les virus enveloppés
... de virus différant en termes de génome, de cycle de réplication et de mode d’assemblage des virions (Figure 1) [10] ...quatorze virus regroupant des virus à ARN négatif (le virus de la ... Voir le document complet
5
Wildlife reservoir for Hepatitis E virus, Southwestern France
... (4), and seroprevalence among blood donors has reached ...boars and deer, has yet to be ...cuniculus), and coypu (Myocastor coypus) and, thus, the potential for these animals to act as ... Voir le document complet
4
Toll-like receptor 2 senses hepatitis C virus core protein but not infectious viral particles.
... dependent signaling: stably transfected CHO cells expressing human TLR2 and/or TLR4 on 18. their cell surface and a reporter gene allowing detecting ligand-induced TLR activati[r] ... Voir le document complet
25
Sujets connexes