[PDF] Top 20 Pyramidal neurons derived from human pluripotent stem cells mature to form functional synapses in vitro and integrate e ciently into mouse brain circuits in vivo
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Pyramidal neurons derived from human pluripotent stem cells mature to form functional synapses in vitro and integrate e ciently into mouse brain circuits in vivo
... Pyramidal neurons derived from human pluripotent stem cells mature to form functional synapses in vitro and integrate efficiently into mouse brain circuits in vivo. Monday, 29.[r] ... Voir le document complet
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Pyramidal Neurons Derived from Human Pluripotent Stem Cells Integrate Efficiently into Mouse Brain Circuits In Vivo
... of functional cells from stem cells in a dish? Chair: Ellen Goossens, Petra De Sutter 13:30–14:00 Prof Susana CHUVA DE SOUSA LOPES , Leiden University, The ... Voir le document complet
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Pyramidal Neurons Derived from Human Pluripotent Stem Cells Integrate Efficiently into Mouse Brain Circuits In Vivo
... Understanding brain development: from the embryo to human brain organoids 10:30 Coffee 11:00 Malin Parmar – Lund University, Sweden Generation of authentic and subtype-specific ... Voir le document complet
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en fr Adipose-derived mesenchymal stem cells in the treatment of rheumatoid arthritis : in vitro and in vivo approaches Les cellules souches mésenchymateuses dérivées du tissu adipeux dans le traitement de la polyarthrite rhumatoïde : approches in vitro et in vivo
... macrophages in vitro, nous avons mis en évidence que les RASF pourraient fonctionnellement affecter ce potentiel ...utilisé in vitro avec des concentrations très élevées d IFN- et TNF (de l ... Voir le document complet
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CNS disease models with human pluripotent stem cells in the CRISPR age
... comes from poor access to nutrients and oxygen, and poor excretion of the more soluble toxic metabolic byproducts ...lactate). In order to avoid these one must limit the greatest ... Voir le document complet
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Conditional Induction of Math1 Specifies Embryonic Stem Cells to Cerebellar Granule Neuron Lineage and Promotes Differentiation into Mature Granule Neurons
... increase in the neuronal markers Tuj1 and MAP2, and a decrease in GFAP and Olig2 upon Math1 induction (Dox) ...increase in the number of Tuj1 and MAP2 positive ... Voir le document complet
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Gene delivery to pancreatic exocrine cells in vivo and in vitro
... the functional beta cell mass in diabetic patients but it is seriously hampered by donor ...beta cells by reprogramming more readily available cell types unaffected by the ...nar cells, the ... Voir le document complet
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Adipose-Derived Stem Cells from Systemic Sclerosis Patients Maintain Pro-Angiogenic and Antifibrotic Paracrine Effects In Vitro
... result in constitutive activation of fibroblasts and fibrosis affecting skin and multiple ...results in a polymorphous spectrum of clinical and pathologic manifestations of SSc [ 1 ... Voir le document complet
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Deconstructing transcriptional heterogeneity in pluripotent stem cells
... exposed to chemical and genetic perturbations (A) Shown are the average Ct values and standard deviations for technical triplicates (error bars on x-axis) or biological triplicates (error bars on ... Voir le document complet
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Embryo-derived and induced pluripotent stem cells: Towards naive pluripotency and chimeric competency in rabbits
... rbiPSCs and rbESCs into rabbit pre-implantation embryos and chimeric competency Chimeric competency defines the capacity of PSCs to massively colonise a pre-implantation embryo and ... Voir le document complet
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In vitro modeling of the neurovascular environment by coculturing adult human brain endothelial cells with human neural stem cells.
... Abstract Brain and vascular cells form a functionally integrated signalling network that is known as the neurovascular unit ...paracrine and juxtacrine) between different elements of ... Voir le document complet
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Urine-sample-derived human induced pluripotent stem cells as a model to study PCSK9-mediated autosomal dominant hypercholesterolemia
... 5 and Bertrand Cariou 1,2,3,4 ABSTRACT Proprotein convertase subtilisin kexin type 9 (PCSK9) is a critical modulator of cholesterol ...(ADH) and premature atherosclerosis, PCSK9 loss-of-function (LOF) ... Voir le document complet
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Differentiation of Human Pluripotent Stem Cells into Colonic Organoids via Transient Activation of BMP Signaling
... epithelium in frogs, mice, and ...frogs and mice, consistent with the known role of BMP in posterior-ventral development (Kumar et ...signaling in PSC- derived gut tube cultures ... Voir le document complet
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Effect of mono-(2-ethylhexyl) phthalate on human and mouse fetal testis: In vitro and in vivo approaches
... out in animal models have established the toxic effects of phthalates on testicular ...fically, in the rat, in utero exposure to phthalates leads to male reproductive disorders, ... Voir le document complet
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A novel micronucleus in vitro assay utilizing human hematopoietic stem cells
... 1000–2500 cells per second with a threshold in forward scatter (FSC) set to include all intact ...capability and available at SciLifeLab BioVis platform at Uppsala University in Sweden, ... Voir le document complet
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Generation of induced pluripotent stem cells-derived hepatocyte-like cells for ex vivo gene therapy of primary hyperoxaluria type 1
... therapy and the severity of the disease, PH1 is an attractive target for gene therapy, providing both a long-lasting and less costly method for AGT delivery to the ...liver. In vivo ... Voir le document complet
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Functional analysis of HOXD9 in human gliomas and glioma cancer stem cells.
... samples and cell lines All tumor tissue specimens were obtained from patients with glioma who underwent surgery at the Department of Neurosurgery, Keio University School of Medicine and the ... Voir le document complet
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Differentiable PKC activation on pacemaking activity of cardiomyocytes derived from mouse embryonic stem cells
... used mouse embryonic stem cells derived cardiomyocytes with 1 µM PMA introduced for 48h whereas he used 1 µM of PMA on neonatal rat cardiomyocyte for only 24 ...role in conflicting ... Voir le document complet
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In Vitro Corticogenesis from Embryonic Stem Cells Recapitulates the In Vivo Epigenetic Control of Imprinted Gene Expression
... Zdbf2 in ESC-derived neural cells and brain, respectively ( Duffie et ...with, and could be due to the aberrant hypermethylation of the maternal allele of Zdbf2- DMR, as ... Voir le document complet
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Insights into brain microstructure from $in\ vivo$ DW-MRS
... NAA, and those of water in the same two volumes of interest in the human corpus callosum (CC) ( Upadhyay et ...). From the microstructural investigation stand point, the CC offers the ... Voir le document complet
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