[PDF] Top 20 Plasmacytoid dendritic cells and dermatological disorders: focus on their role in autoimmunity and cancer.
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Plasmacytoid dendritic cells and dermatological disorders: focus on their role in autoimmunity and cancer.
... Abstract Dendritic cells (DC), considered as immunological sentinels of the organism since they are antigen presenting cells, create the link between innate and adaptive ...myeloid ... Voir le document complet
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Plasmacytoid dendritic cells deficient in IFNα production promote the amplification of FOXP3+regulatory T cells and are associated with poor prognosis in breast cancer patients
... for their role in antiviral immunity as they massively produce Type I interferons (IFNα/β/ω) in response to viral nucleic acids recog- nized by Toll-like receptor 7 and 9 (TLR7 ... Voir le document complet
4
Production of large numbers of plasmacytoid dendritic cells with functional activities from CD34+ hematopoietic progenitor cells: use of IL-3
... ), and cancer. As pDC represent a rare cell type in the peripheral blood, the goal of this study was to develop a new method to efficiently generate large numbers of cells from a limited ... Voir le document complet
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Plasmacytoid Dendritic Cells Are Largely Dispensable for the Pathogenesis of Experimental Inflammatory Bowel Disease
... Inflammation and Autoimmunity, MedImmune LLC, Gaithersburg, MD, United States, 4 Department of Medicine, New York University School of Medicine, New York, NY, United States, 5 CNRS-UMR, Immunoconcept, ... Voir le document complet
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Role of DC-SIGN in Lassa Virus Entry into Human Dendritic Cells
... DC-SIGN in MDDC correlates with enhanced LASV ...isolates and that productive infection causes virus-induced perturbation of their antigen-presenting function ( 5 , 6 ...genetically and ... Voir le document complet
12
Role of myosin IIA in the small intestine immunosurveillance by dendritic cells
... B-1- In the lumen of the small intestine The small intestine is the long proximal part of the gut, linking the stomach to the ...crypts and 3) lamina ...epithelial cells that give rise to ...immune ... Voir le document complet
168
Peripheral Blood Plasmacytoid Dendritic Cells at Day 100 Can Predict Outcome after Allogeneic Stem Cell Transplantation
... proportion and obtained 2 comparable groups. In the Kaplan-Meier analysis, the OS was signi fi- cantly lower in the low pDC as compared with the high pDC group, and this difference was con ... Voir le document complet
7
Role of RhoA/ROCK pathway in angiogenesis and their potential values in prostate cancer treatment
... prostate cancer and treated by radical ...score and follow-up were ...tumor cells and the highest Gleason score (index ...96°C in Sodium Citrate Solution (10 mM, pH ...4°C ... Voir le document complet
124
A focus on mast cells and pain
... stress and aging ( Dropp, 1976; Aydin et al., 1998 ). They are more numerous in females than in males ( Goldschmidt et ...). In accordance with these results, centrally injected SCF was not ... Voir le document complet
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Bovine lactoferrin-induced CCL1 expression involves distinct receptors in monocyte-derived dendritic cells and their monocyte precursors
... secretion in Mo and ...receptors and some TLRs [ 27 , 36 – 41 ...receptors in triggering bLF effects in human primary Mo and MoDCs is still poorly known, it is of interest that ... Voir le document complet
12
Zika Virus Inhibits IFN-a Response by Human Plasmacytoid Dendritic Cells and Induces NS1-Dependent Triggering of CD303 (BDCA-2) Signaling
... (NS1) and two structural proteins, the envelope (E) and the membrane precursor ...cooperate in vitro to help the virus evade interferon-mediated antiviral response ( 51 ...). In particular, ... Voir le document complet
15
Stimulation of olfactory receptors in cancer cells exacerbates their invasiveness and propensity to generate metastases
... BON cells were transiently transfected to express OR1G1 or OR17-40 receptors or mock- ...transfected. Cells were seeded onto collagen type I gels and stimulated by the respective odorant ligands of ... Voir le document complet
2
Targeting Metabolism to Induce Cell Death in Cancer Cells and Cancer Stem Cells
... by cancer cells to provide macromolecules is glutaminolysis, which generates reductive equivalents such as NADPH by replenishing the TCA cycle [ 4 ...acid in the sense that, under normal conditions, ... Voir le document complet
14
MicroRNAs: molecular features and role in cancer.
... miR-21 and miR-182, which control the expression of FAS-L (247) and protein FADD (248), ...step in tumor progression (249, ...siRNAs in endothelial ...decrease in angiogenesis, by a ... Voir le document complet
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en fr Role of suppressive myeloid cells and immune infiltrates in cancer Rôles des cellules myéloïdes suppressives et des infiltrats immunitaires dans le cancer
... Nos résultats concernant l’infiltrat immunologique au sein des métastases hépatiques sont comparables à ceux décrits au niveau de la tumeur primitive où une densité élevée en lymphocytes T mémoires et en T régulateurs ... Voir le document complet
159
Protease-Activated Receptors in the Intestine: Focus on Inflammation and Cancer
... PARs IN INFLAMMATORY BOWEL DISEASES Inflammatory Bowel Diseases (IBD) The IBD, Crohn’s disease (CD) and ulcerative colitis (UC), are chronic diseases causing inflammation of the gut ( 92 ...worldwide. ... Voir le document complet
14
Absence of MHC class II on cDC1 dendritic cells triggers fatal autoimmunity to a cross-presented self-antigen
... preparations and isolation from tissues Cells were isolated from the ear skin as described ...37°C in RPMI 1640 containing Liberase TL ...Corp.) and deoxyribonuclease I (DNase I) ...Medicons ... Voir le document complet
13
en fr Modulation of dendritic cells and macrophages : implication in cancer and atherosclerosis Modulation des cellules dendritiques et macrophages : implications dans le cancer et l'athérosclérose
... cytotoxiques in vivo Un traitement par imiquimod, un agoniste de TLR-7/8, en application locale à des patients porteurs de carcinome basocellulaire a été suivi d’une régression tumorale au niveau clinique, et ... Voir le document complet
128
How Cells feel their environment: a focus on early dynamic events.
... frequency and several nanometer amplitude 44,45 ...topography and dynamics near a surface is shown on ...understood. In two sets of experiments based on micropipette and biomembrane force ... Voir le document complet
13
Vitamin D and musculoskeletal health, cardiovascular disease, autoimmunity and cancer: Recommendations for clinical practice.
... resulted in a significant reduction of PTH, triglycerides and TNF-alpha compared to placebo, however the LDL-cholesterol concentration increased in the supplementation ...study in 18,225 men ... Voir le document complet
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