[PDF] Top 20 Normal-appearing white matter in multiple sclerosis is in a subtle balance between inflammation and neuroprotection
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Normal-appearing white matter in multiple sclerosis is in a subtle balance between inflammation and neuroprotection
... nicole.schaeren-wiemers@unibas.ch Multiple sclerosis is a chronic inflammatory disease of the ...injury and diffuse inflammatory damage has been shown in the chronic phase of the ... Voir le document complet
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Magnetization transfer ratio measures in normal-appearing white matter show periventricular gradient abnormalities in multiple sclerosis
... In multiple sclerosis, there is increasing evidence that demyelination, and neuronal damage occurs preferentially in cortical grey matter next to the outer surface of the ... Voir le document complet
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Interaction between Neurons and the Oligodendroglial Lineage in Multiple Sclerosis and Its Preclinical Models
... decades and is comprehensively discussed in a recent review by [ 89 ...ment and differentiation comes from multiple observations: ...OL and OPC depletion by ethidium ... Voir le document complet
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The expression profile of matrix metalloproteinases (MMPs) and their inhibitors (TIMPs) in lesions and normal appearing white matter of multiple sclerosis
... active inflammation, and in most of matched NAWM ...TNF-α/β and IL (interleukin)-2, known modulators of MMPs, was upregulated only in distinct stages of lesion formation, while their ... Voir le document complet
11
The IL‐27/IL‐27R axis is altered in CD4 + and CD8 + T lymphocytes from multiple sclerosis patients
... IL-12 is reduced in MS patients Pro-inflammatory Th1/Tc1 and Th17/Tc17 subsets contribute to the pathobiology of MS and ...polarisation in animal models of MS has been ...involved ... Voir le document complet
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Decision-making in multiple sclerosis patients: a systematic review
... feedback and deliberation ...presented a learning curve, moving gradually away from risky choices toward safer ones in the course of the ...trials. In 2 of 4 studies using the IGT MS patients ... Voir le document complet
10
Detection of Multiple Pathways in the Spinal Cord White Matter Using Q-Ball Imaging
... demonstrated in this study, QBI can retrieve crossing fibre information in an ex vivo spinal cord, whereas the DTI approach is constrained by its single diffusion ...fibres in the brain [9] ... Voir le document complet
5
Relation between functional brain imaging, cognitive impairment and cognitive rehabilitation in patients with multiple sclerosis
... plasticity and cognitive rehabilitation So far, fMRI studies have shown spontaneous processes of functional reorganisation in the MS ...regions is as- sumed to be related to compensatory mechanisms ... Voir le document complet
5
en fr Molecular magnetic resonance imaging and biological barriers inflammation in models of multiple sclerosis Imagerie par résonnance magnétique moléculaire et inflammation des barrières biologiques dans les modèles de sclérose en plaques
... 187 Cusi, D., Damotte, V., Defer, G., Delgado, S. R., Deloukas, P., di Sapio, A., Dilthey, A. T., Donnelly, P., Dubois, B., Duddy, M., Edkins, S., Elovaara, I., Esposito, F., Evangelou, N., Fiddes, B., ... Voir le document complet
206
Autobiographical memory facilitation in multiple sclerosis: a neuropsychological and neuroimaging approach
... J ´er ˆome 1,3 ; Sellal, Franc¸ois 4 and Manning, Lilianne 1 . 1 Laboratoire d’Imagerie et de Neurosciences Cognitives, University of Strasbourg, Strasbourg, France 2 Laboratoire Octogone, University le Mirail, ... Voir le document complet
1
Voxel-Based quantitative MRI reveals spatial patterns of grey matter alteration in multiple sclerosis
... MS and 7 secondary progressive MS) and 36 healthy con- trols (HC), matched for age and gender, free from neurological or psy- chiatric ...age between 18 and 65 years, (b) Expanded ... Voir le document complet
10
white matter damage in perinatal brain
... hormone is the single most predictive measure of outcome obtainable on serum in the first week of life ...25) and perhaps hyperoxia ( PO2 > 60) 4. Hypocapnia ( PCO2 < 25) and perhaps ... Voir le document complet
31
Modeling multiple sclerosis in laboratory animals
... there is now a plethora of different animal models available, each of them serving the purpose to study specific aspects of the pathogenesis of MS in ...useful and have provided a ... Voir le document complet
17
Voxel-Based Quantitative MRI reveals spatial patterns of grey matter alteration in Multiple Sclerosis
... evidence and potential clinical importance of grey matter (GM) pathology in multiple sclerosis (MS), assessing GM damage by conventional magnetic resonance imaging (MRI) remains ...aim ... Voir le document complet
3
Gender and sex hormones in multiple sclerosis pathology and therapy.
... It is yet unclear which progestagen (progesterone, progestins) will lead to the best outcome in recent menopausal ...estrogens in HRT for menopausal women to prevent hyperplasia of the endometrium ... Voir le document complet
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Vitamin D/CD46 Crosstalk in Human T Cells in Multiple Sclerosis
... cells in patients with MS. (A) t-SNE representation and (B) intensity of staining of CD46, CD25, CD162, CD45RA, CD127, CD146, CD6, Foxp3 and CD226 in CD3+CD4+ T cell clusters of PMBCs ... Voir le document complet
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Organising white matter in a brain without corpus callosum fibres
... pregnancy, between 14 and 18 weeks of gestation (Ren et al 2006), and displays a protracted maturation throughout childhood and adolescence (Lebel, et ...hypoplasia, is a ... Voir le document complet
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Evidence of a relation between hippocampal volume, white matter hyperintensities, and cognition in subjective cognitive decline and mild cognitive impairment
... described a cognitive continuum from being without symptoms, to expressing a subjective complaint, to being objectively impaired, all in parallel with an accumulation of neuropathological markers ... Voir le document complet
11
Caffeine, cognitive functioning, and white matter lesions in the elderly: establishing causality from epidemiological evidence.: caffeine and white matter lesions
... functions in this context: firstly, by taking large population samples it is able to represent a full range of cognitive impairments due to multiple causes, and not restricted to small ... Voir le document complet
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Plasma Amyloid Is Associated with White Matter and Subcortical Alterations and Is Modulated by Age and Seasonal Rhythms in Mouse Lemur Primates
... levels in mouse lemurs. Statistical parametric maps depicting regions in which the probability of voxels belonging to white matter or subcortical nuclei increases with Aβ 40 plasma levels ... Voir le document complet
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