[PDF] Top 20 N6-methyl-adenine: an epigenetic signal for DNA-protein interactions.
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N6-methyl-adenine: an epigenetic signal for DNA-protein interactions.
... control DNA-protein interactions avoids the problem created by the high mutability of m5C, which undergoes relatively high frequencies of deamination, giving rise to thymine 101 ...as an ... Voir le document complet
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Methyl Adenine Identification (MadID): High-Resolution Detection of Protein-DNA Interactions
... Chemiluminescence signal obtained is analysed using the ChemiDoc Imaging ...isolated DNA regions: example of telomere purification by ...genomic DNA from step ...17). An example of the ... Voir le document complet
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An epigenetic switch involving overlapping fur and DNA methylation optimizes expression of a type VI secretion gene cluster
... access for the RNA polymerase ...showed an overrepre- sentation of GATC motifs, which are targets for the DNA adenine methylase ...the adenine of the GATC ...modulates ... Voir le document complet
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Undetectable levels of N6-methyl adenine in mouse DNA: Cloning and analysis of PRED28, a gene coding for a putative mammalian DNA adenine methyltransferase.
... a N6-DNA methyltransferase in mammalian ...coding for a putative N6- DNA methyltransferase, has been found in murine and human ...critical for the enzymatic activity of the ... Voir le document complet
24
Structural basis for Fe–S cluster Assembly and tRNA thiolation mediated by IscS protein–protein interactions
... proteins for the IscS dimer, their Fe-loading state (IscU, CyaY, and IscX), as well as their relative concentrations together presumably dictate which combination(s) of partner proteins interact with IscS at any ... Voir le document complet
19
Development of chemogenomic approaches for prediction of protein - ligand interactions
... with protein information, and the ulti- mate goal is to identify all possible interactions between ligands and proteins of the ...the protein-ligand space makes any systematic experimental ... Voir le document complet
160
Epigenetic modifications in an imprinting cluster are controlled by a hierarchy of DMRs suggesting long-range chromatin interactions
... analysed for each region and time point is listed in the legend to Figure ...2B). For both DMR1 and 2, there was some increase in methylation on the paternal allele in whole embryonic day 9 (E9) fetuses (to ... Voir le document complet
11
DNA methyl transferases are differentially expressed in the human anterior eye segment
... 0.05) for subsequent analysis of the ...unsuitable for grafting due to serolog- ical ...used for corneal and trabeculum samples after ...0.05) for subsequent analysis of the ... Voir le document complet
6
Generation of a versatile BiFC ORFeome library for analyzing protein-protein interactions in live Drosophila
... potential interactions, we asked whether hits from the large-scale interaction screen could somehow be confirmed to contribute to Hox protein ...searched for a sensitive genetic background where any ... Voir le document complet
25
A Cas9 with PAM recognition for adenine dinucleotides
... new adenine-rich PAM ...possibility for SmacCas9 requiring less GC-content in its PAM was supported by sequence similarities to the "QQR” variant that has 5 0 - NAAG-3 0 specificity 27 , in addition to ... Voir le document complet
7
PALMA, an improved algorithm for DOSY signal processing
... value for λ should be chosen from assumptions on the data based on explicit previous knowledge, however on a practical point, this is not ...analysed for most non-null values of λ, with the better results ... Voir le document complet
34
Large-scale prediction of protein-protein interactions from structures
... of an increasing number of protein 3D structures is likely to continue at a fast pace as a result of several large-scale ...both an opportunity and a challenge for in silico prediction ... Voir le document complet
10
The current landscape of coronavirus-host protein-protein interactions
... enrichments for “Ribosome”, “RIG-I-like receptor signaling”, “Endocyto- sis”, “Spliceosome” and “Phagosome” pathways (Table 1 c and Additional file 1 : Table ...importance for these viruses to control the ... Voir le document complet
16
High-resolution AFM imaging of single-stranded DNA-binding (SSB) protein--DNA complexes
... ABSTRACT DNA in living cells is generally processed via the generation and the protection of single-stranded DNA involving the binding of ssDNA-binding pro- teins ...like DNA repair and ...nucleo- ... Voir le document complet
8
Femtosecond spectroscopic study of carminic acid–DNA interactions
... studied for decades in an effort to optimize their therapeutic function for the treatment of various human ...with DNA [1-4]. The formation of drug-DNA complexes is determined by the ... Voir le document complet
34
Gene x environment Interactions in Autism Spectrum Disorders: Role of Epigenetic Mechanisms
... adjusting for maternal epilepsy and parental psychiatric history, or restricting the analysis to children without congeni- tal malformations), whereas this increased risk was not observed for other ... Voir le document complet
18
Protein contacts, inter-residue interactions and side-chain modelling.: protein contacts
... of protein structures that control most of biological ...relationship for a better understanding of protein fold and to perform structural prediction from ...Nonetheless, protein secondary ... Voir le document complet
39
An analysis of representations for protein structure prediction
... where i represents the type of secondary structure; TP is the number of true positives (correct predictions of that secondary structure); TN is the number of true negat[r] ... Voir le document complet
279
Protein interactions of the transcription factor Hoxa1.
... screening for candidate interactors of ...Hoxa1 interactions identified, 45 could be validated by in vivo affinity binding assays in co-transfected animal ...integrins signal transduction ...41 ... Voir le document complet
17
Creating and analyzing pathway and protein interaction compendia for modelling signal transduction networks
... “bypass interactions” we asked how many different routes link EGF to a downstream ...is an NP-hard prob- lem, but, by setting an upper limit on path length the prob- lem is computationally ...MAPK3 ... Voir le document complet
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