[PDF] Top 20 Metabotropic glutamate receptor 5 in bulimia nervosa
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Metabotropic glutamate receptor 5 in bulimia nervosa
... monoamine receptor systems, altered mGlu5 might contribute to BN symptoms indirectly, by impacting dopamine and serotonin signalling 13 , 55 – 59 ...because, in our current study we did not assess monoamine ... Voir le document complet
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Metabotropic glutamate receptor 5 in bulimia nervosa
... 5 Center for Radiopharmaceutical Science of ETH, PSI, and USZ, Department of Chemistry and Applied Biosciences of ETH, 8093 Zürich, Switzerland 6 Psychiatry Research Unit, University of Fribourg, Chemin du ... Voir le document complet
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Pharmacological evidence for a metabotropic glutamate receptor heterodimer in neuronal cells
... cultured in Dulbecco’s modified Eagle’s medium (Thermo Fischer Scientific, Courtaboeuf, France) supplemented with 10% (vol/vol) fetal bovine serum (Sigma Aldrich) in a P2 cell culture ...plated in ... Voir le document complet
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Asymmetric functioning of dimeric metabotropic glutamate receptors disclosed by positive allosteric modulators.: Asymmetric Functioning of a GPCR Dimer
... dimerization in G-protein activation since all are constitutive dimers, either homodimers linked by a disulfide bridge (4,5), or obligatory heterodimers ...neurotransmitters, glutamate and GABA, the ... Voir le document complet
14
Higher ambient synaptic glutamate at inhibitory versus excitatory neurons differentially impacts NMDA receptor activity
... EPSCs in inter- ...responses in inhibitory neurons but not excitatory neurons in the hippocampus by GNE-8324 16 ...EPSCs in inhibitory neurons under varying ...μm in the slices, which ... Voir le document complet
14
Role of the N-terminal region in G protein-coupled receptor functions: negative modulation revealed by 5-HT2B receptor polymorphisms.
... (7TMRs) in receptor functions, such as ligand binding, surface expression, signaling, and desensitization, vary depending on the size and structure of the ...that in some 7TMRs, the N-terminus ... Voir le document complet
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AMPA-sst2 somatostatin receptor interaction in rat hypothalamus requires activation of NMDA and/or metabotropic glutamate receptors and depends on intracellular calcium.
... n=3), in agreement with calculated GHK reversal potentials in our experimental conditions (GABA : -50 mV, glutamate : +13 mV, AMPA : +13 ...shown in Figure 2A and 2B, mixed ... Voir le document complet
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Surface expression of metabotropic glutamate receptor variants mGluR1a and mGluR1b in transfected HEK293 cells.
... variants in cells expressing either of each variant alone and in ...variant in protein extracts from cells transfected singly were comparable with corresponding protein amounts in cells co- ... Voir le document complet
29
Activation of a Dimeric Metabotropic Glutamate Receptor by Inter-Subunit Rearrangement
... rearrangement in the activation of a dimeric GPCR, we chose a metabotropic glutamate receptor (mGluR) as a ...Moreover, glutamate and its analogues do not bind to the TMD of an mGluR, ... Voir le document complet
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Chloride ions stabilize the glutamate-induced active state of the metabotropic glutamate receptor 3
... Miladinovic, T., Nashed, M. G., Singh, G., 2015. Overview of Glutamatergic Dysregulation in Central Pathologies. Biomolecules 5, 3112-3141. Monn, J. A., Henry, S. S., Massey, S. M., Clawson, D. K., Chen, ... Voir le document complet
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A polymorphism in the glutamate metabotropic receptor 7 is associated with cognitive deficits in the early phases of psychosis
... assessment In the FEP cohort, DNA were sampled from whole-blood for each Caucasian participant and extracted following classical ...either in NMDA- or metabotropic glutamate receptors ... Voir le document complet
28
Heptahelical domain of metabotropic glutamate receptor 5 behaves like rhodopsin-like receptors.
... mGlu 5 , DFB is devoid of agonist activity on the wild-type receptor (it is not able to activate the full length receptor by itself) ...as glutamate on the full length ...exist in at ... Voir le document complet
30
A long-lasting calcium-activated nonselective cationic current is generated by synaptic stimulation or exogenous activation of group I metabotropic glutamate receptors in CA1 pyramidal neurons.
... mV in 1 sec (ramp ...concentration in the C sGlu pipette solution) and were connected to a common pressure ...pipette in a position in which its orifice was approximately one-half of the ... Voir le document complet
15
The glutamate receptor GluK2 contributes to the regulation of glucose homeostasis and its deterioration during aging
... 2013. Glutamate, glutamate receptors, and downstream signaling ...islets: glutamate signaling in endocrine cells. Trends in Endocrinology and Metabolism 27:177 e188 ...differences ... Voir le document complet
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Les implications normatives de la conceptualisation de l'anorexia nervosa
... approches les plus utilisées en psychiatrie. Ce qui nous permettra d’établir un lien entre l’approche thérapeutique en clinique et le concept d’espèce en philosophie. Ainsi, il est utile de faire un état des lieux ... Voir le document complet
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Disruption of spatial task performance in anorexia nervosa
... dysfunction. In fact, we used techniques and a conceptual framework that had been used successfully in neuroscience research with patients suffering from parietal lesions ...significance in the ... Voir le document complet
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Functional studies of the 5′-untranslated region of human 5-HT4 receptor mRNA
... the 5’ UTR of the h5-HT 4 receptor in human atria extended at least upstream of position –2340 bp from the ATG codon (data not ...The 5’ UTR was further explored by carrying out nested PCR on ... Voir le document complet
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New therapeutic opportunities for 5-HT2 receptor ligands
... cultured in the presence of the selective 5-HT 2B receptor antagonist RS127445 exhibited a significant increase in neutral lipid levels compared to control cells (Söhle, et ...peripheral ... Voir le document complet
47
Heart and anorexia nervosa
... anorexia nervosa Abdallah Fayssoil 1,2,3 & Jean Claude Melchior 1 & Mouna Hanachi 1 Abstract Anorexia nervosa, one of the more frequent and severe eating disorders, is a chronic psychiatric disease ... Voir le document complet
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5-HT2A receptor polymorphism gene in Bipolar Patients and Harm Avoidance personality trait
... of 5-HT2a receptor polymorphism to bipolar disorder or to HA personality trait in normal and bipolar subjects ...the 5-HTR2a receptor polymorphism in bipolar disorder and HA ... Voir le document complet
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