[PDF] Top 20 Mechanism of insulin resistance in a rat model of kidney disease and the risk of developing type 2 diabetes

... Chronic kidney disease is associated with homeostatic imbalances such as insulin resis- ...However, the underlying mechanisms leading to these imbalances and whether they promote ... Voir le document complet

... Abstract Diabetes mellitus is associated with increased risk for cardiovascular disorders, which are major causes of mortality in this ...independent risk factor for the ... Voir le document complet

... Introduction Type 2 diabetes (T2D) is a chronic progressive metabolic disease characterized by hyperglycaemia, due to insulin resistance/insufficient insulin ... Voir le document complet

... author and co-authors if applicable retain copyright ownership and moral rights in this ...Neither the whole thesis or dissertation, nor substantial extracts from it, may be printed or ... Voir le document complet

... The results suggest that 11 patients with IGT would need to be treated for ...event of development of ...reduced risk of developing T2DM irrespective of age, sex, ... Voir le document complet

... inhibitors and cardiovascular risk Numerous studies have evidenced a role for GLP-1 in the cardiovascular ...On the one hand, continuous IV administration of GLP-1 ... Voir le document complet

... become a cornerstone treatment in the primary and sec- ondary prevention of atherosclerotic cardiovascular disease ...4,5 Kidney diseases, notably acute kidney ... Voir le document complet

... significance. In contrast, women in the first quintile of HOMA2-%B ...levels of insulin secretion) showed significantly increased odds of developing DepS compared ... Voir le document complet

... causes of morbidity and mortality including cardiovascular dis- eases (CVD), retinopathies, nephropathies and neuropa- ...percent of people living with T2D die of cardiovascular ... Voir le document complet

... renal disease (ESRD) requiring hemodialysis 152 ...studies in patients with T2DM to explore the relationship of exenatide clearance (CL/F) and CL CR ...RI and ESRD groups were ... Voir le document complet

... to the Editor 867 mesothelial cells,” but, to our knowledge, these authors never employed immunohistochemical analysis in any of their published papers on peritoneal biopsy ...guish the ... Voir le document complet

... is a multi-disciplinary open access archive for the deposit and dissemination of sci- entific research documents, whether they are pub- lished or ...not. The documents may come from ... Voir le document complet

... Evolution of silent myocardial ischaemia prevalence and cardiovascular disease risk factor management in Type 2 diabetes over a 10-year period: an ... Voir le document complet

... Received: 4 September 2009 / Accepted: 22 September 2009 # The Author(s) 2009. This article is published with open access at Springerlink.com Keywords Allocation bias . Causality . Ethics . Inclusion criteria . ... Voir le document complet

... for the management of T2DM. By inhibiting GLP-1 degradation and increasing circulating levels, thereby promoting insulin secretion and reducing glucagon secretion, both in ... Voir le document complet

... The right (with lesion) side of the brain showed enhanced mGluR5 binding characteristics, suggesting a complementary and compensatory role of metabotropic glutamate rece[r] ... Voir le document complet

... University of Liege, Belgium. Background and Aims: Type 2 diabetes is a progressive disease with associated insulin resistance and diminished ... Voir le document complet

... Maxwell and Breslow, 2004; Park et ...Horton a démontré que le plasma des souris transgéniques avait la capacité de réduire l'expression du LDLR chez les souris témoins parabiosées et d'augmenter leur ... Voir le document complet

... interactions. The mammalian mitochondrial respiratory‐chain complex 1 is a large L‐shaped membrane‐ bound redox enzyme (also known as NADH:ubiquinone oxidoreductase) consisting of 14 core subunits ... Voir le document complet

... Strengths of the present study include the fact that it comprised a large number of women with a 6-year follow-up, taking into account different pharmacological classes of ... Voir le document complet