[PDF] Top 20 CXC ligand 5 is an adipose-tissue derived factor that links obesity to insulin resistance.
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CXC ligand 5 is an adipose-tissue derived factor that links obesity to insulin resistance.
... loss is associated with a decrease of 10 in serum CXCL5 concentration (median: 2230 versus 2040 pg/ml, p % = 0,006), suggesting that CXCL5 circulating concentration is controlled by WAT ( ...mediates ... Voir le document complet
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CXC Ligand 5 Is an Adipose-Tissue Derived Factor that Links Obesity to Insulin Resistance
... L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d’enseignemen[r] ... Voir le document complet
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Chemokine Expression in Inflamed Adipose Tissue Is Mainly Mediated by NF-κB
... as an excess of body fat mass, is a major risk for developing type 2 diabetes caused from the systemic insulin ...resistance. Obesity-induced insulin resistance is ... Voir le document complet
10
Visceral Fat Accumulation During Lipid Overfeeding Is Related to Subcutaneous Adipose Tissue Characteristics in Healthy Men
... Due to the limited amount of adipose tissue available, we were unable to verify the change at the protein level and to extend the study to additional ...transcription ... Voir le document complet
9
Overexpression of Bcl-2 is associated with apoptotic resistance to the G-quadruplex ligand 12459 but is not sufficient to confer resistance to long-term senescence.
... G-overhang is prone to form a four-stranded G-quadruplex structure that has been shown to inhibit telomerase activity in vitro ...molecules that stabilize G-quadruplex are effective as ... Voir le document complet
14
Insulin is a potent myeloma cell growth factor through insulin/IGF-1 hybrid receptor activation.
... ; insulin ; IGF-1 ; IGF-1R ; INSR ; insulin/IGF-1 hybrid receptor Introduction Many reports have documented a role of insulin as well as of IGF-1 as growth factors in a variety of cancers .... ... Voir le document complet
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Relationships between glycaemic abnormalities, obesity and insulin resistance in nondiabetic Polynesians of New Caledonia.
... according to the WHO ...sent to Noumea central ...plasma insulin (FPI) was measured by radioimmunoassay (RIAgnost, Behring, Los Angeles, CA) at the Henri Mondor Hospital, Créteil, ... Voir le document complet
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Differential effect of long-term leucine supplementation on skeletal muscle and adipose tissue in old rats: an insulin signaling pathway approach
... order to prevent the fall of plasma BCAA concentrations induced by leucine supple- mentation as previously described (Rieu et ...glycine to render the diets isocaloric and to balance the amino acid ... Voir le document complet
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Complement activation links inflammation to dental tissue regeneration
... hypothesized to complement the activity of the innate immune system ...activation is initiated by fixation of antibodies to pathogen surface antigens [14, ...Complement is activated after ... Voir le document complet
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Adipose tissue fibrosis assessed by high resolution ex vivo MRI as a hallmark of tissue alteration in morbid obesity
... standard to detect and quantify tissue fibrosis (15,16). Others aimed to quantify adipose tissue fibrosis using different modalities such as immunohistochemistry (11) and polarized ... Voir le document complet
8
Studies of the enzymes that convert steroid hormones in the human adipose tissue
... agonist, insulin, dexamethasone and ...17-N,N-diethylcarbamoyl-4-methyl-4-aza- 5-androstan-3-one (4-MA) or finasteride (Sigma, Oakville, ON, ...added to the medium prior to preadipocyte ... Voir le document complet
276
Seipin deficiency alters brown adipose tissue thermogenesis and insulin sensitivity in a non-cell autonomous mode
... energy is supplied, their body temperature dropped in less than five hours when ...us to better characterize the energetic flux and supply in these ...intolerant to fasting and entered into torpor ... Voir le document complet
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A common polymorphism in the 5′ UTR of ERCC5 creates an upstream ORF that confers resistance to platinum-based chemotherapy
... ERCC5 is downstream from DNA-PKcs Following bulky adduct DNA damage, signaling through DNA-PKcs (a critical DNA damage kinase) is required for the selective translational activation of NER enzymes in ... Voir le document complet
8
Human adipose stromal-vascular fraction self-organizes to form vascularized adipose tissue in 3D cultures
... subcutaneous adipose tissue (At) is well organized into unilocular adipocytes interspersed within dense ...structure is completely lost under standard culture conditions and may impair the ... Voir le document complet
11
Cushing Syndrome Is Associated With Subclinical LV Dysfunction and Increased Epicardial Adipose Tissue
... Thirty-eight patients with ACTH-dependent CS (19 active and 19 in remission for at least 2 years, mean 41.2± 4.2 months) and 19 controls of similar age and sex distribution were included. A magnetic resonance imaging was ... Voir le document complet
7
Osteoprotegerin in relation to insulin resistance and blood lipids in sub-Saharan African women with and without abdominal obesity
... 18 to 40 years, of which 44 obese and 16 non obese were re- cruited within the general population of Edéa, ...ence to the nearest 0.5 cm, and weight in light clothes to the nearest ...with an ... Voir le document complet
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Cathepsin-D, a key protease in breast cancer, is up-regulated in obese mouse and human adipose tissue, and controls adipogenesis.: Cathepsin D, adipogenesis and obesity
... 6A). To evaluate the consequences of cath-D silencing on adipocyte differentiation, we analysed the cellular lipid levels in adipocytes which had or had not been silenced for cath-D at day 7 of differentiation ... Voir le document complet
25
Phosphatidylglycerols are induced by gut dysbiosis and inflammation, and favorably modulate adipose tissue remodeling in obesity
... interactions that regulate meta- bolic ...intervention that restored gut microbial ...demonstrated that LPS induces PG release. Acute PG treatment in mice altered adipose tissue gene ... Voir le document complet
15
Impact of inflammation on the metabolic changes associated with obesity : dialogues between adipose tissue and the intestine
... isomer to cause a lipoatrophic syndrome in mice (Clement, Poirier et ...WAT to control the local and systemic changes provoked by this external ...stressor. To answer to the question, we ... Voir le document complet
251
Muscle regeneration with intermuscular adipose tissue (IMAT) accumulation is modulated by mechanical constraints
... due to its earlier implication in adipogenesis [ 39 ...known to promote skeletal muscle regeneration after injury in healthy muscle [ 19 , 25 ...showed that FAP proliferation and macrophage- like ... Voir le document complet
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