[PDF] Top 20 Kinase C substrates and synaptic plasticity in Aplysia
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Kinase C substrates and synaptic plasticity in Aplysia
... Understanding how memories are stored and retrieved has been the goal of work in several scientific disciplines, including neuroscience, neuropsychology, psychology, and cognitive scienc[r] ... Voir le document complet
194
Alternative Functions of Core Cell Cycle Regulators in Neuronal Migration, Neuronal Maturation, and Synaptic Plasticity
... polo-boxes and play important roles during cell cycle progression and genotoxic stress (Barr et ...localization and recognition of phosphorylated substrates via polo-box domains ...identified ... Voir le document complet
28
Activity-Dependent p25 Generation Regulates Synaptic Plasticity and Aβ-Induced Cognitive Impairment
... slices in the presence of calpeptin substantially reduced p25 levels, suggesting that calpain is required for activity-dependent p25 liberation (Figure ...(AMPARs) and NMDA receptors (NMDARs), which mainly ... Voir le document complet
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Neuronal AMP-activated protein kinase hyper-activation induces synaptic loss by an autophagy-mediated process
... as synaptic pruning, occurs during adolescence in humans, synaptic loss in adults is associated with cognitive impairments and is an early hallmark of neurodegenera- tive diseases ... Voir le document complet
16
LTP inhibits LTD in the hippocampus via regulation of GSK3beta.: A role for GSK3beta in synaptic plasticity
... GSK3β kinase assay after LTD – To measure GSK3 activity in hippocampal slices following electrode induced LTD (900 stimuli delivered at 3 Hz) microdissected areas of slices were solubilized and 30 ... Voir le document complet
46
The role of GSK-3 in synaptic plasticity.
... GSK-3 and the neurodevelopmental hypothesis of ...synthase kinase 3beta, and this dephosphorylation involves protein phosphatases 2A and 2B in SH-SY5Y human neuroblastoma ... Voir le document complet
33
Regulation of glutamatergic neurotransmission, synaptic plasticity, sleep and behavior by D2-GSK3B-FXR1
... result in modulation of AKT and GSK3 activity (Beaulieu et ...serine-threonine kinase which is involved in the regulation of synaptic plasticity, monoamine transporter ... Voir le document complet
296
Chronic Sodium Selenate Treatment Restores Deficits in Cognition and Synaptic Plasticity in a Murine Model of Tauopathy
... Querfurth and LaFerla, 2010; Masters et ...cortex and the hippocampus to the isocortical areas has been reported to correlate well with cognitive deficits and disease ...pathology and not ... Voir le document complet
16
en fr Conditions for the emergence of corticostriatal synaptic plasticity Conditions pour l'apparition de plasticité synaptique corticostriatale
... glutamate in astrocytes following uptake may alternatively be deami- nated to form a-ketoglutarate and enter the TCA cycle (McKenna, 2007; Robinson and Jackson, 2016; Stobart and Anderson, ... Voir le document complet
297
Cellular and synaptic network defects in autism
... [40] and up to 45% of patients also fulfill the diagnostic criteria for ASD ...Hamartin and tuberin form a complex that participates in the inhibition of the mammalian target of rapamycin (mTOR) ... Voir le document complet
13
Abnormal AMPAR-mediated synaptic plasticity, cognitive and autistic-like behaviors in a missense Fmr1 mutant mouse model of Fragile X syndrome
... incubated in standard artificial cerebrospinal fluid (ACSF; 119 mM NaCl, ...carbogen, and then for 45 min at RT. Recordings were performed in ACSF continuously oxygenized with carbogen at 33-35°C ... Voir le document complet
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en fr AMP-activated protein kinase : Screening for novel membrane substrates and creatine kinase phosphorylation linked to specific subcellular compartment La protéine kinase activée par AMP : Criblage de nouveaux substrats membranaires et phosphorylation de la créatine kinase liée à une compartimentation subcellulaire
... synthesis and translocation (Mayinger and Meyer, ...identified in mammals, although ATP transport across the ER membranes has been shown (Hirschberg et ...tested in future ...analyzed ... Voir le document complet
132
CD4+ T Cells Have a Permissive Effect on Enriched Environment-Induced Hippocampus Synaptic Plasticity
... patch-clamped in the whole- cell ...neuron in the living slice while still connected with the rest of the neuronal ...µM) in the bath ...TTX) and miniature (in the presence of 2 µM TTX) ... Voir le document complet
14
CD4 + T Cells Have a Permissive Effect on Enriched Environment-Induced Hippocampus Synaptic Plasticity
... “CTGTCTCTTATACACATCT” and the front adaptor sequence “AAGTCGCAGGGTTG” using cutadapt (version ...pattern in accordance with the UMI design N4H4 (N = ATCG, H = ATC) followed by a stretch of ...frequent ... Voir le document complet
14
Area-specific alterations of synaptic plasticity in the 5XFAD mouse model of Alzheimer's disease: dissociation between somatosensory cortex and hippocampus
... applied in this ...captured in order to accurately map the synaptic signals recorded in the different areas of the brain ...slice and the electrode ...located in the Schaffer ... Voir le document complet
10
Synaptic and non-synaptic communication between neurons and oligodendrocyte precursor cells in the somatosensory cortex
... The identification of the channel mediating this inward current was achieved in 1995, with the report of a novel ATP-dependent inward rectifier potassium channel predominantly expressed [r] ... Voir le document complet
178
Lipids and synaptic functions
... Lipids and synaptic functions Fanny Mochel 1,2,3 Abstract Synaptic functions have long been thought to be driven by proteins, especially the SNARE complex, contrasting with a relatively passive role ... Voir le document complet
7
Myotonic dystrophy CTG expansion affects synaptic vesicle proteins, neurotransmission and mouse behaviour.: Synaptic dysfunction in myotonic dystrophy
... (LTD) and Long Term Potentiation (LTP) were assessed on male DMSXL homozygotes and wild-type controls, aged seven months (I/O, PPF and LTD) or four months ...processed in oxygenated buffer ... Voir le document complet
39
en fr Roles of astroglial cannabinoid type 1 receptors (CB1) in memory and synaptic plasticity Rôles du récepteur aux cannabinoïdes de type 1 des astrocytes dans la mémoire et la plasticité synaptique
... brain and then to the final depth using an automatic micropositioner (MIM100-2, M2E, ...placed in the correct area using a micromanipulator (UNI-Z, M2E, ...response. In vivo recordings of evoked ... Voir le document complet
227
HISTOCHEMISTRY AND ULTRASTRUCTURE OF THE CRYPT CELLS IN THE DIGESTIVE GLAND OF APLYSIA PUNCTATA (CUVIER, 1803)
... 1994) and many prosobranchs (Mason & Nott, 1981) are known to accumu- late inorganic salts under normal ...occurs in specialized cells of the digestive tubules, called crypt cells (calcium cells) which ... Voir le document complet
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