[PDF] Top 20 Intestinal microbiota determines development of non-alcoholic fatty liver disease in mice
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Intestinal microbiota determines development of non-alcoholic fatty liver disease in mice
... gut microbiota, and it was recently shown that diabetes- sensitive and diabetes-resistant mice are associated with a spe- ci fic gut ...11 In the present study, we first submitted mice of ... Voir le document complet
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DEP domain-containing mTOR-interacting protein suppresses lipogenesis and ameliorates hepatic steatosis and acute-on-chronic liver injury in alcoholic liver disease
... deletion of SIRT1 disrupts DEPTOR signaling, promotes mTORC1 activation, and exacerbates the development of alcoholic fatty liver and liver injury in mice ... Voir le document complet
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Pathogenic role of IL-15 in non-alcoholic fatty liver disease
... survival of immune ...part of IL-2 receptor, which is the prototypic member of this family (Takeshita, ...1992). In human patients the deficiency in the gene encoding this receptor ... Voir le document complet
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Intracellular lipids are an independent cause of liver injury and chronic kidney disease in non alcoholic fatty liver disease-like context
... utilization of G6P, a common substrate for both lipid and glycogen synthesis, markedly induces these anabolic pathways in ...increase in de novo lipogenesis [11,17,19,21,43] . In addition, our ... Voir le document complet
17
Identifying PGC-1α-dependent hepatokines in a non-alcoholic fatty liver disease murine model
... Parkinson’s disease (97). A few studies show increased SERPINA3N expression in the hypothalamus in response to high fat diet (98, ...evidence of SERPINA3N implication in NAFLD ...role ... Voir le document complet
82
Endoplasmic Reticulum stress signaling and the pathogenesis of Non-Alcoholic Fatty Liver Disease
... used in combination with modified diets to induce a robust steatosis to NASH ...foz/foz mice are an overnutrition model featuring obesity, diabetes and ...foz/foz mice developed NASH with fibrosis, ... Voir le document complet
56
The purinergic p2x7 receptor-nlrp3 inflammasome pathway: A new target in alcoholic liver disease?
... involvement of the P2X7R- NLRP3 inflammasome pathway in the induction of non-alcoholic fatty liver disease (NAFLD) and liver fibrosis, suggesting possible ... Voir le document complet
14
In Vitro and In Vivo Models of Non-Alcoholic Fatty Liver Disease: A Critical Appraisal
... model of NASH comprising high sucrose (40%) and fat (10%) but lacking the nutrients methionine and choline, which are essential components in animal and human nutrition [ 92 ...precursor of ... Voir le document complet
19
Roles of Ceramides in Non-Alcoholic Fatty Liver Disease
... role of ceramides is even less clear when exploring mice models invalidated for enzymes of the sphingolipid ...Indeed, mice heterozygous for aSMase or treated with an aSMase inhibitor are ... Voir le document complet
20
Impact of bacterial probiotics on obesity, diabetes and non-alcoholic fatty liver disease related variables: a systematic review and meta-analysis of randomised controlled trials
... Results of meta-analyses: overall estimates and estimates obtained in specific study populations: (A) anthropometric variables and BMI, (B) glucose homeostasis, (C) liver ...difference in mean ... Voir le document complet
13
Fettleber und Lipidstoffwechsel = Fatty liver disease and lipid metabolism
... können in der Leber zu einer ver- mehrten Fettdeposition führen und Weg- bereiter der NAFLD ...und in der Leber gebildet und freigesetzt werden, sind wichtige pathogenetische Mediatoren der ... Voir le document complet
8
Can intestinal microbiota be associated with non-intestinal cancers ?
... communities of micro-organisms ...circulating in host populations, but also to global changes in our microbiota 3 ...functions in the homeostasis of our body, resulting in ... Voir le document complet
11
Characterization Of Intestinal Microbiota In Celiac Children
... enlisted in the study after informed consent was achieved by their parents and the Ethics Committee of the faculty of Medicine - Oran- ...screening of celiac disease was carried out on ... Voir le document complet
11
Rôle du régulateur du cycle cellulaire p16INK4a dans le développement du diabète de type 2 et dans les maladies métaboliques du foie gras ou NAFLD (Non-Alcoholic Fatty Liver Disease) : rôle de p16INK4a dans le contrôle de la néoglucogenèse hépatique et dans le développement de la stéatose hépatique non alcoolique.
... Storage Disease), caractérisée par une accumulation excessive de lipides et par une ...et non-adipeux tels que le foie, le muscle et le cœur entraînant de nombreuses complications cardiovasculaires et une ... Voir le document complet
117
Nutrigenomics of high fat diet induced obesity in mice suggests relationships between susceptibility to fatty liver disease and the proteasome
... independent of NAFLD susceptibility. Beyond analyses of expression of individual genes, the use of a single genome-wide gene expression platform, interrogating transcript abundance for the ... Voir le document complet
13
Nonalcoholic fatty liver disease and obstructive sleep apnea
... seen in the OSA group since they did not display severe CIH anymore [35]. In contrast, the majority of studies demonstrate a link between these two chronic ...Using non-invasive surrogate ... Voir le document complet
28
Bile acid retention and activation of endogenous hepatic farnesoid-X-receptor in the pathogenesis of fatty liver disease in ob/ob-mice
... implicated in the pathophysiology of non- alcoholic fatty liver disease because selective FXR-agonists improve glucose and lipid metabolism in rodent models ... Voir le document complet
9
Magnetic resonance-based biomarkers in nonalcoholic fatty liver disease and nonalcoholic steatohepatitis
... detection of NAFLD and NASH: T1, corrected T1 and multiparametric MRI There are currently no direct methods clinically available to assess disease activity including ballooning and inflammation in ... Voir le document complet
10
AIEC infection triggers modification of gut microbiota composition in genetically predisposed mice, contributing to intestinal inflammation
... claims in published maps and institutional ...reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Cre- ative Commons ... Voir le document complet
15
Whole Rye Consumption Improves Blood and Liver n-3 Fatty Acid Profile and Gut Microbiota Composition in Rats
... Analysis of polyphenolic compounds from refined and whole rye diets Polyphenolic compounds were analyzed using an Accela UHPLC 1250 equipped with a linear ion-trap mass spectrometer (LTQ XL, Thermo Fisher ... Voir le document complet
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