[PDF] Top 20 Intestinal dysbiosis in Inflammatory Bowel Disease associated with primary immunodeficiency.
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Intestinal dysbiosis in Inflammatory Bowel Disease associated with primary immunodeficiency.
... Patients with IBD in remission were recruited at the Gastroenterology Department of the Saint Antoine Hospital (Paris, France) and provided informed consent (local ethics committee: Comité de Protection des ... Voir le document complet
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en fr Impact of Inflammatory bowel disease associated dysbiosis in the intestinal ecosystem Conséquences physiopathologiques de la dysbiose associée aux maladies inflammatoires chroniques de l'intestin.
... 25 b. Etudes animales Les modèles murins de colite expérimentale fournissent des arguments expérimentaux solides pour incriminer la microflore intestinale dans la pathogenèse d’une colite. En effet, dans la plupart des ... Voir le document complet
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Characterization of Human Colon Organoids From Inflammatory Bowel Disease Patients
... Mutations in the type VII collagen gene COL7A1 are associated with IBD ( Freeman et ...collagen in keratinocyte polarity ( Dayal et ...proposed in intestinal epithelial cells, ... Voir le document complet
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Management of patients with inflammatory bowel disease and spondyloarthritis
... (madcam-1), in vascular and lymphatic vessels of the gut 107,108 , previous demonstration of α4β7 integrin in the joint 109 led to the expectation of a therapeutic efficacy in ...SpA. In ... Voir le document complet
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Role of bacteria in the etiopathogenesis of inflammatory bowel disease
... involved in chronic antigenic stimulation leading to T-cell and macrophage ...infection. In contrast to its behavior within intestinal epithelial cells [37] , CD-associated bacterial ... Voir le document complet
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De-escalation of immunomodulator and biological therapy in inflammatory bowel disease.
... patients with Crohn’s disease receiving combination therapy with immunomodulators and infliximab for at least 6 months were randomly assigned to either continue or stop ...difference in the ... Voir le document complet
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Culturing human intestinal stem cells for regenerative applications in the treatment of inflammatory bowel disease
... performed in order to avoid the process of finding suitable cell donors, as well as circumventing the risk for tissue rejection and the need for further immunomodula- tory therapy due to the procedure ...patients ... Voir le document complet
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Importance of Bacteria as Trigger in Inflammatory Bowel Disease
... Micro-organisms in IBD Etiology IBD, such as CD and UC, preferentially occur in the colon and distal ileum, which contain the highest intestinal bacterial concentrations ...agents in the ... Voir le document complet
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Evidence for non-neutralizing autoantibodies against IL-10 signalling components in patients with inflammatory bowel disease.
... an immunodeficiency due to impaired release of pro- inflammatory cytokines by macrophages ...several primary immunodeficien- cies that are characterized by IBD-like phenotypes such as IPEX syndrome, ... Voir le document complet
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Vedolizumab Therapy is Ineffective for Primary Sclerosing Cholangitis in Patients With Inflammatory Bowel Disease: A GETAID Multicentre Cohort Study
... concentrations in patients with IBD and PSC, despite clear evidence of its effectiveness in active intestinal ...malignancy in this patient popula- tion. Overall our findings, together ... Voir le document complet
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Is Parkinson’s disease a chronic low-grade inflammatory bowel disease?
... was associated with a decreased risk for subsequent PD, suggesting that vagal innervation may be involved in the development of PD [41, ...observed in the brain of DSS-treated mice, such as ... Voir le document complet
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Genetic and microbial factors modulating the ubiquitin proteasome system in inflammatory bowel disease
... CYLD in CD as revealed by CD-associated bacteria The genetic results point towards the implication of CYLD in IBD ...CYLD in T84 intestinal epithelial cells. In AIEC LF82 ... Voir le document complet
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The laminin response in inflammatory Bowel disease: protection or malignancy?
... identified in neoplastic progression of UC [10–12] and were shown to promote inflammation induced progression into intestinal cancer ...[13]. Inflammatory responses are often associated ... Voir le document complet
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[Immunopathogenesis of inflammatory bowel disease.]
... Aberrant intestinal expression and allelic variants of mucin genes associated with inflammatory bowel ...DPC4 in carcinomas arising in inflammatory bowel ... Voir le document complet
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CD8+CD28- regulatory T lymphocytes prevent experimental inflammatory bowel disease in mice.
... fixed in 10% buffered ...stained with hematoxylin and eosin and used for microscopic assessment of ...colitis in a blinded ...mucosal inflammatory cell infiltrates with or without ... Voir le document complet
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Fecal microbiota transplantation in inflammatory bowel disease: the quest for the holy grail
... therapy in IBD but more studies are needed to define the best indications, optimal timing, frequency, mode of delivery and the optimal donor for each ...player in intestinal homeostasis with ... Voir le document complet
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Increased incidence of systemic serious viral infections in patients with inflammatory bowel disease associates with active disease and use of thiopurines
... outcomes in adult patients with inflammatory bowel ...thiopurines in adult and elderly patients with inflammatory bowel ... Voir le document complet
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Crohn's disease patients' and gastroenterologists' perspectives towards de-escalating inflammatory bowel disease therapy.
... “mess with a good thing”, and worry over having to go back on ...providers) in the US and Europe who would never consider de-escalating therapy if there is any chance of their disease flaring ... Voir le document complet
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CCDC88B is required for pathogeneisis of inflammatory bowel disease.
... SNPs in the studied region in silico. The in silico eQTL are simulated such that they explain the same variance as the true ...eQTL with compute a corresponding “simulated ...for ... Voir le document complet
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Chemotherapy-driven dysbiosis in the intestinal microbiome
... partitioned into a training set (including 90% of the patients) and a validation set (including the remaining 10%). The random forest classi fier was trained on the 90% and used to predict the outcome of the held out 10%. ... Voir le document complet
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