[PDF] Top 20 Interaction of Cisplatin with Adenine and Guanine: A Combined IRMPD, MS/MS, and Theoretical Study
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Interaction of Cisplatin with Adenine and Guanine: A Combined IRMPD, MS/MS, and Theoretical Study
... as cisplatin (cis-[Pt(NH 3 ) 2 Cl 2 ]), is a widely-used anticancer drug that has been particularly successful in treating different types of tumors (lung, ovarian, testicular, head, and ... Voir le document complet
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Interaction of Cisplatin with 5′-dGMP: A Combined IRMPD and Theoretical Study
... channel and the calculations carried out for the cis-[Pt(NH 3 ) 2 (5’- dGMP)-H] + complex, which demonstrate the greater affinity of cis-[Pt(NH 3 ) 2 ] + for the nucleobase rather than for the phosphate ... Voir le document complet
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Undervalued N3 Coordination Revealed in the Cisplatin Complex with 2′-Deoxyadenosine-5′-monophosphate by a Combined IRMPD and Theoretical Study
... mode and the stretching of the C6=N bond, as mentioned previously (vide ...The IRMPD spectra of the cis-[PtCl(NH 3 ) 2 (5’-dAMP)] + complex show that the sampled ionic population comprises two ... Voir le document complet
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Definition of a RACK1 Interaction Network in Drosophila melanogaster Using SWATH-MS
... buffer and separated by SDS-PAGE. Proteins bands were in-gel digested with trypsin before being submitted to liquid chroma- tography MS ...N- and C-terminally tagged protein in mock- ... Voir le document complet
11
Comparison between Immunoassay, GC/MS/MS and HRGC/HRMS on different fly ashes.
... the MS/MS measurements based on calculation of each 2,3,7,8-congener contribution regarding their WHO ...TEQ/g of sample. The correlation coefficient for this plot is 0.84 with a ... Voir le document complet
4
Binding Interaction of HMGB4 with Cisplatin-Modified DNA
... mechanism of the action of cisplatin is repair shielding ...binding of HMGB1 to the platinated lesion inhibits damage repair either by preventing its recognition by cellular proteins or by ... Voir le document complet
24
Comparison of approaches to deal with matrix effects in LC-MS/MS based determinations of mycotoxins in food and feed
... concentrations of labelled mycotoxins. OPIC and IPD should, at first, show some ...sample and relative signal (OPIC) or isotopomer abundances (IPD) are directly measured in ...method and in ... Voir le document complet
22
Insights into Cisplatin Binding to Uracil and Thiouracils from IRMPD Spectroscopy and Tandem Mass Spectrometry
... beamline of the free electron laser (FEL) of the Centre Laser Infrarouge d’Orsay (CLIO) [48, ...energy of the FEL was set at ...region of interest and ensure a fairly stable ... Voir le document complet
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MS/MS-Guided Isolation of Clarinoside, a New Anti-Inflammatory Pentalogin Derivative
... structure of 2, dehydroxylation could occur at several positions of each of the two sugars; in order to know on which side of the compound 2 the dehydroxylation site was located, the ... Voir le document complet
10
Optimal Size of Nanoparticles for Magnetic Hyperthermia: A Combined Theoretical and Experimental Study
... on a model system consisting of iron MNPs in a size range going from ...simulations of hysteresis loops and analytical ...increase of coercive field with the size ... Voir le document complet
24
Theoretical Study of the Interaction of Electron Donor and Acceptor Molecules with Graphene
... values of the freestanding TTF ...molecule and the graphene layer, defined as the distance between the middle C=C bond and the graphene layer depends on the xc-functional ... Voir le document complet
36
Quantitative metabolism of natural and antiviral nucleosides and nucleotides in human cells by LC-MS/MS
... chromatogram, and decreasing background noise. 2 " -dA may act as a silanol-masking agent, which would prevent the non-specific binding of the analytes to the ...effect with other ... Voir le document complet
152
Dosage des catécholamines et des métabolites par LC-MS/MS
... •les catécholamines urinaires de 24 heures et plasmatiques •les métanéphrines urinaires de 24 heures et plasmatiques •les autres tests…. •L’imagerie par tomodensitométrie et RMN •L’image[r] ... Voir le document complet
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Comparison of HRGC-MS/MS and HRGC-HRMS results on environmental and food samples in some European laboraratories
... PCCD/Fs and interferents, such as polychlorobiphenyls, and 13 C 12 -PCDF and native PCDD whose isotopic clusters overlap, HRMS was necessary because only HRMS had the sensitivity and ... Voir le document complet
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Phenolic compounds in apple juices - Method of quantification by UHPLC-UV and UHPLC-MS/MS
... by a PhD grant funding from the SFR 149 QUASAV (Structure Fédérative de Recherche: Qualité et Santé du Végétal), Angers, ...team of “Horticulture Experimental Unit” of INRA Angers-Nantes who takes ... Voir le document complet
1
Analysis of radiation induced DNA damage by LC-MS/MS in isolated and cellular DNA
... Formation of 5mC products in cellular DNA Several • OH-induced decomposition products of 5mC, cytosine and thymine were measured as a function of radiation dose in cellular DNA (Table ... Voir le document complet
181
Validated quantitative simultaneous determination of cocaine, opiates and amphetamines in serum by UHPLC-MS/MS
... determination of cocaine, opiates and amphetamines in serum by ultra-high performance liquid chromatography coupled to tandem mass spectrometry (UHPLC-MS/MS) allowed to replace favourably gas ... Voir le document complet
1
A nutraceutical extract from Inula viscosa leaves: UHPLC-HR-MS/MS based polyphenol profile, and antioxidant and cytotoxic activities
... activity of neuroblastoma, epatoblastoma and colorectal carcinoma cell lines was mark- edly affected by IvE, and, with the sole exception of HepG2 cells, already at the lowest tested ... Voir le document complet
11
Analytical criteria for use of MS/MS for determination of dioxins and dioxin-like PCBs in feed and food
... definition of the working range, especially focusing on the lower end of the working range, - linearity, reproducibility and robustness of the systems, - applicability in routine analysis, - ... Voir le document complet
4
Proper Alignment of MS/MS Spectra from Unsequenced Species
... advantage of the notion of ...potential with the notion of possible positions. We then deal with the practical issues of setting the parameters of PSA in order to obtain ... Voir le document complet
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