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Reduced-Intensity Conditioning With Fludarabine and Busulfan Versus Fludarabine and Melphalan for Patients With Acute Myeloid Leukemia: A Report From the Acute Leukemia Working Party of the European Group for Blood and Marrow Transplantation
... BACKGROUND: Fludarabine plus busulfan (FB) and fludarabine plus melphalan (FM) are 2 widely used reduced-intensity conditioning (RIC) regimens for allogeneic ... Voir le document complet
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Unrelated cord blood transplantation for adult patients with acute myeloid leukemia: Higher incidence of acute graft-versus-host disease and lower survival in male patients transplanted with female unrelated cord blood-a report from Eurocord, the Acute Leukemia Working Party, and the Cord Blood Committee of the Cellular Therapy and Immunobiology Working Party of the European Group for Blood and Marrow Transplantation
... estimating the cumulative incidence of chronic GVHD, death was considered as a competing ...OS and leukemia-free survival (LFS) were estimated using the Kaplan-Meier ...test ... Voir le document complet
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Unrelated cord blood transplantation for adult patients with acute myeloid leukemia: higher incidence of acute graft-versus-host disease and lower survival in male patients transplanted with female unrelated cord blood—a report from Eurocord, the Acute Leukemia Working Party, and the Cord Blood Committee of the Cellular Therapy and Immunobiology Working Party of the European Group for Blood and Marrow Transplantation
... effects of chronic GVHD? Previous studies in the bone marrow or peripheral blood setting have demonstrated a strong link between chronic GVHD occurrence and a lower risk ... Voir le document complet
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Anti-thymocyte globulin for graft-versus-host disease prophylaxis in patients with intermediate- or high-risk acute myeloid leukaemia undergoing reduced-intensity conditioning allogeneic stem cell transplantation in first complete remission - a survey on behalf of the Acute Leukaemia Working Party of the European Society for Blood and Marrow Transplantation
... prophylaxis with or without anti-T-cell globulin in haematopoietic cell transplantation from matched unrelated donors: a randomised, open-label, multicentre phase 3 ...trial. The Lancet ... Voir le document complet
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Outcome of haploidentical versus matched sibling donors in hematopoietic stem cell transplantation for adult patients with acute lymphoblastic leukemia: a study from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation
... Patients and methods Study design and data collection This was a retrospective, multicenter analysis using the dataset of the ALWP of the ...EBMT. The ... Voir le document complet
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Clinical practice recommendation on hematopoietic stem cell transplantation for acute myeloid leukemia patients with FLT3internal tandem duplication: A position statement from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation
... AML patients over a median follow-up of 39 months for surviving ...Twenty-eight patients received post-transplant sorafenib maintenance treatment, initiated at a median of ... Voir le document complet
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Allogeneic hematopoietic cell transplantation with cord blood versus mismatched unrelated donor with post-transplant cyclophosphamide in acute myeloid leukemia
... design and data collection This was a retrospective multicenter analysis using the dataset of the Acute Leukemia Working Party (ALWP) of the ... Voir le document complet
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Prediction of Allogeneic Hematopoietic Stem-Cell Transplantation Mortality 100 Days After Transplantation Using a Machine Learning Algorithm: A European Group for Blood and Marrow Transplantation Acute Leukemia Working Party Retrospective Data Mining Study
... model for overall mortality (OM) at day 100. The ADT consists of alternating levels of prediction (ellipses) and decision nodes ...associated with a weight, representing ... Voir le document complet
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Umbilical cord blood versus unrelated donor transplantation in adults with primary refractory or relapsed acute myeloid leukemia: a report from Eurocord, the Acute Leukemia Working Party and the Cord Blood Committee of the Cellular Therapy and Immunobiology Working Party of the EBMT.
... Patients and Methods Data collection This is a retrospective, multicenter registry-based study performed by the Acute Leukemia Working Party (ALWP) of ... Voir le document complet
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Impact of conditioning intensity in T-replete haplo-identical stem cell transplantation for acute leukemia: a report from the acute leukemia working party of the EBMT
... cell transplantation (haplo-SCT) is an attractive transplant procedure since it provides a possibility of transplantation to almost all patients needing an allogeneic ...approaches ... Voir le document complet
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Salvage use of allogeneic hematopoietic stem cell transplantation after reduced intensity conditioning from unrelated donors in multiple myeloma. A study by the plasma cell disorders subcommittee of the european group for blood and marrow transplant chronic malignancies working party
... 96% and 89% in the MUD, MMUD and CB groups, respectively. Acute graft-versus-host disease (GvHD) grade II-IV occurred in 33%, 41% and 42% of patients in the ... Voir le document complet
4
The impact of HLA-matching on reduced intensity conditioning regimen unrelated donor allogeneic stem cell transplantation for acute myeloid leukemia in patients above 50 years—a report from the EBMT acute leukemia working party
... feasibility of haplo-identical SCT performed with T replete stem cell grafts and in vivo T cell depletion based either on ATG [32] or post-transplant cyclophos- phamide [33] has been demonstrated in ... Voir le document complet
15
Intravenous busulfan for autologous stem cell transplantation in adult patients with acute myeloid leukemia: a survey of 952 patients on behalf of the Acute Leukemia Working Party of the European Group for Blood and Marrow Transplantation
... Data from 952 adult AML patients undergoing intravenous busulfan-based conditioning prior to ASCT from January 2003 to December 2011 were reported to the Acute ... Voir le document complet
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Transplant Outcomes for Secondary Acute Myeloid Leukemia: Acute Leukemia Working Party of the European Society for Blood and Bone Marrow Transplantation Study.
... criteria for this analysis included adult patients (ages > 18 years) with a diagnosis of ...sAML. Patients with sAML were defined as patients di- agnosed ... Voir le document complet
9
Umbilical cord blood versus unrelated donor transplantation in adults with primary refractory or relapsed acute myeloid leukemia: a report from Eurocord, the Acute Leukemia Working Party and the Cord Blood Committee of the Cellular Therapy and Immunobiology Working Party of the EBMT
... Patients and Methods Data collection This is a retrospective, multicenter registry-based study performed by the Acute Leukemia Working Party (ALWP) of ... Voir le document complet
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The Sequence of Cyclophosphamide and Myeloablative Total Body Irradiation in Hematopoietic Cell Transplantation for Patients with Acute Leukemia
... r a c t Limited clinical data are available to assess whether the sequencing of cyclophosphamide (Cy) and total body irradiation (TBI) changes ...evaluated the sequence in 1769 (CyTBI, ... Voir le document complet
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Dexamethasone in hyperleukocytic acute myeloid leukemia
... white blood cells. In silico studies, primary samples, leukemic cell lines, and xenograft mouse models were used to explore the antileukemic activity of ...difference with respect to ... Voir le document complet
12
Allogeneic stem cell transplantation for AML patients with RUNX1 mutation in first complete remission: a study on behalf of the acute leukemia working party of the EBMT.
... about the impact of runt-related transcription factor 1 (RUNX1) gene mutation on char- acteristics and outcome of patients with de novo acute myeloid ... Voir le document complet
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Clofarabine/busulfan-based reduced intensity conditioning regimens provides very good survivals in acute myeloid leukemia patients in complete remission at transplant: a retrospective study on behalf of the SFGM-TC
... using the log rank test for OS and LFS and the Gray test for ...considered for univariate analysis were the conditioning regimen (CloB2A2 vs CloB2A1), ... Voir le document complet
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Inferior outcome of allogeneic stem cell transplantation for secondary acute myeloid leukemia in first complete remission as compared to de novo acute myeloid leukemia
... Besides the classical risk factors, i.e., cytogenetics and age, as well as donor type, our data identify sAML as an independent intrinsic factor for inferior outcome after alloSCT in ...patient ... Voir le document complet
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