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[PDF] Top 20 Integration of an in vitro blood brain barrier model with organic electrochemical transistors

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Integration of an in vitro blood brain barrier model with organic electrochemical transistors

Integration of an in vitro blood brain barrier model with organic electrochemical transistors

... consists of a very selective barrier formed of brain microvascular endothelial cells which restrict the passage of substances from the blood to the brain ...number ... Voir le document complet

167

Zika virus crosses an in vitro human blood brain barrier model

Zika virus crosses an in vitro human blood brain barrier model

... infection of the i-BECs was identi- ied 24 h post-exposure to the virus by immunoluo- rescence ...detected in cell lysates by Western blotting after only a 2-h exposure ...viable with no visible ... Voir le document complet

10

Setting-up an in vitro model of rat blood-brain barrier (BBB): a focus on BBB impermeability and receptor-mediated transport

Setting-up an in vitro model of rat blood-brain barrier (BBB): a focus on BBB impermeability and receptor-mediated transport

... Setting-up an In Vitro Model of Rat Blood-brain Barrier (BBB): A Focus on BBB Impermeability and Receptor-mediated ...The blood brain barrier ... Voir le document complet

18

Peripheral Routes to Neurodegeneration: Passing Through the Blood–Brain Barrier

Peripheral Routes to Neurodegeneration: Passing Through the Blood–Brain Barrier

... for brain barriers and neuroinflammation is becoming important ( Braniste et ...impact of the gut microbiome composition on CNS health was reported ( Amedei and Boem, 2018 ; Chu et ...permeability in ... Voir le document complet

15

Blood–brain-barrier organoids for investigating the permeability of CNS therapeutics

Blood–brain-barrier organoids for investigating the permeability of CNS therapeutics

... separately with a test compound for confocal fluorescence microscopy (option ...bear in mind that confocal fluorescence microscopy can only be done if the compound of interest is inherently ... Voir le document complet

32

From Blood to Lesioned Brain: An In Vitro Study on Migration Mechanisms of Human Nasal Olfactory Stem Cells

From Blood to Lesioned Brain: An In Vitro Study on Migration Mechanisms of Human Nasal Olfactory Stem Cells

... transcripts with a fold change above 2.5 were upregulated in the lesioned ...indicating in particular that 53% of these genes are involved in immune and inflammatory ...members of ... Voir le document complet

19

Study of the antiepileptic drugs transport through the immature blood-brain barrier

Study of the antiepileptic drugs transport through the immature blood-brain barrier

... search of single nucleotide polymorphisms (SNP) in these transporters ...distribution of the AEDs, or an increase in the elimination of these drugs (Löscher et ...analyzed ... Voir le document complet

198

Recent Advances on Ultrasound Contrast Agents for Blood-Brain Barrier Opening with Focused Ultrasound

Recent Advances on Ultrasound Contrast Agents for Blood-Brain Barrier Opening with Focused Ultrasound

... addition of microbubbles has reduced the amount of ultrasound energy required to open the BBB by 100-fold ...oscillations of the bubble become unstable ...present in the vascular endothelial ... Voir le document complet

31

Antibody Neutralization of HIV-1 Crossing the Blood-Brain Barrier

Antibody Neutralization of HIV-1 Crossing the Blood-Brain Barrier

... Department of Virology, Institut Pasteur, Université de Paris, Paris, France h CNRS UMR 3569, Université de Paris, Paris, France ABSTRACT HIV-1 can cross the blood-brain barrier (BBB) to ... Voir le document complet

12

Lithographic fabrication, electrical characterization and proof-of-concept demonstration of sensor circuits comprising organic electrochemical transistors for in vitro and in vivo diagnostics

Lithographic fabrication, electrical characterization and proof-of-concept demonstration of sensor circuits comprising organic electrochemical transistors for in vitro and in vivo diagnostics

... presented in Table ...bond with the GOPS present in the PEDOT:PSS solution and therefore improve the adhesion of the conducting polymer ...wettability of the substrate and facilitates ... Voir le document complet

133

TWEAK/Fn14 pathway modulates properties of a human microvascular endothelial cell model of blood brain barrier.

TWEAK/Fn14 pathway modulates properties of a human microvascular endothelial cell model of blood brain barrier.

... least in part to the increased permeability of the HCMEC ...permeability of our BBB model, and while MMP inhibitors have proven beneficial effects in, for example, animal models ... Voir le document complet

15

The pericyte–glia interface at the blood–brain barrier

The pericyte–glia interface at the blood–brain barrier

... dissemination of sci- entific research documents, whether they are pub- lished or ...institutions in France or abroad, or from public or private research ... Voir le document complet

15

Tissue biodistribution of intravenously administrated titanium dioxide nanoparticles revealed blood-brain barrier clearance and brain inflammation in rat

Tissue biodistribution of intravenously administrated titanium dioxide nanoparticles revealed blood-brain barrier clearance and brain inflammation in rat

... amounts of Ti in- duce activation of BECs and initiate the release of IL-1β, IP-10 and CXCL1, which act in a paracrine way to acti- vate astrocytes/microglia cells in the ... Voir le document complet

21

A novel platform for engineering blood-brain barrier-crossing bispecific biologics

A novel platform for engineering blood-brain barrier-crossing bispecific biologics

... This publication could be one of several versions: author’s original, accepted manuscript or the publisher’s version. / La version de cette publication peut être l’une des suivantes : la version prépublication de ... Voir le document complet

58

Magnetic Resonance Methods for Focused Ultrasound-Induced Blood-Brain Barrier Opening

Magnetic Resonance Methods for Focused Ultrasound-Induced Blood-Brain Barrier Opening

... [(A–C) in the figure]. Reproduced with permission from [ 28 ...capable of reaching up to 1,080 W of local acoustic ...operate in a clinical ...integrated with MRI scanners ... Voir le document complet

19

Strategies used by bacterial pathogens to cross the blood–brain barrier

Strategies used by bacterial pathogens to cross the blood–brain barrier

... expression of the outer membrane protein A (OmpA) is critical for entry and survival inside both PMNs and ...interacts with gp96, an endoplasmic paralog of heat shock pro- tein 90, which may ... Voir le document complet

12

Endosomal trafficking regulates receptor-mediated transcytosis of antibodies across the blood brain barrier

Endosomal trafficking regulates receptor-mediated transcytosis of antibodies across the blood brain barrier

... ‘tracking’ in endo- somal compartments of brain endothelial ...Rat brain endothelial cells were co-incubated with blood-brain barrier (BBB)-crossing FC5, monovalent ... Voir le document complet

15

A drug based model to predict enhanced transdermal and blood brain barrier drug deliverability using ultrasonic methods

A drug based model to predict enhanced transdermal and blood brain barrier drug deliverability using ultrasonic methods

... interact with cellular phospolipid bilayer membranes in the BBB prior to or during drug permeation of the BBB, we have previously used DPhPC to compare possible interaction sites with ... Voir le document complet

19

Blood brain barrier leakage is not a consistent feature of white matter lesions in CADASIL

Blood brain barrier leakage is not a consistent feature of white matter lesions in CADASIL

... form in SVD, and CADASIL in particular, re- main elusive, however it has been suggested that a loss of integrity of the blood brain barrier (BBB) is pivotal in ... Voir le document complet

15

Intracellular sorting and transcytosis of the rat transferrin receptor antibody OX26 across the blood-brain barrier in vitro is dependent on its binding affinity

Intracellular sorting and transcytosis of the rat transferrin receptor antibody OX26 across the blood-brain barrier in vitro is dependent on its binding affinity

... re-probed with β-actin- HRP antibodies (A3854, RRID:AB_262011,Sigma, Oakville, ...mutants of OX26 variants and control antibodies were labeled using Alexa 680 maleimide (A-20344, Thermo Fisher Scientific, ... Voir le document complet

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