[PDF] Top 20 Inferior outcome of allogeneic stem cell transplantation for secondary acute myeloid leukemia in first complete remission as compared to de novo acute myeloid leukemia
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Inferior outcome of allogeneic stem cell transplantation for secondary acute myeloid leukemia in first complete remission as compared to de novo acute myeloid leukemia
... chemotherapy, secondary acute myeloid leukemia (sAML), occurring after antecedent hematologic diseases, previous chemotherapy or radiation, has an inferior prognosis compared ... Voir le document complet
10
Matched and mismatched unrelated donor compared to autologous stem cell transplantation for acute myeloid leukemia in first complete remission: a retrospective, propensity score-weighted analysis from the ALWP of the EBMT
... Keywords: Acute myeloid leukemia (AML), Allogeneic transplantation, Matched (10/10) and mismatched (9/10) unrelated donor transplantation, Autologous transplantation, ... Voir le document complet
15
ABO incompatibility in mismatched unrelated donor allogeneic hematopoietic cell transplantation for acute myeloid leukemia: A report from the acute leukemia working party of the EBMT.
... total of 1,013 AML patients who underwent HLA mismatched allo- geneic stem cell transplantation between 2005 and 2014 was identi- fied and ...most of the patients were transplanted with ... Voir le document complet
8
Allogeneic stem cell transplantation for AML patients with RUNX1 mutation in first complete remission: a study on behalf of the acute leukemia working party of the EBMT.
... Acute myeloid leukemia with runt-related transcription factor 1 gene mutation (RUNX1 + AML) is associated with inferior response rates and outcome after conventional ...analysis ... Voir le document complet
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Transplant Outcomes for Secondary Acute Myeloid Leukemia: Acute Leukemia Working Party of the European Society for Blood and Bone Marrow Transplantation Study.
... T Secondary acute myeloid leukemia (sAML) has been associated with inferior outcomes compared with de novo ...outcomes in sAML after allogeneic hematopoietic ... Voir le document complet
9
Allogeneic hematopoietic cell transplantation with cord blood versus mismatched unrelated donor with post-transplant cyclophosphamide in acute myeloid leukemia
... dataset of the Acute Leukemia Working Party (ALWP) of the European Society for Blood and Marrow Trans- plantation (EBMT) ...group of more than 600 transplant centers that are ... Voir le document complet
12
Allogeneic stem cell transplantation in acute lymphoblastic leukemia and non-Hodgkin's lymphoma for patients <= 50 years old in first complete remission: results of the EORTC ALL-3 trial
... Committee of each participating ...1986 to November 1996 in 20 European ...years of age and younger than 60 years of age with de novo ALL and lymphoblastic non-Hodgkin’s lymphoma ... Voir le document complet
9
A comparison between allogeneic stem cell transplantation from unmanipulated haploidentical and unrelated donors in acute leukemia
... Methods In order to be included in the study, the patients had to fulfill all the following criteria: age ≥18 years; de novo AL; disease status at transplant: complete ... Voir le document complet
9
Outcomes following hematopoietic stem cell transplantation in patients treated with standard chemotherapy with or without gemtuzumab ozogamicin for acute myeloid leukemia
... outcomes in patients who received HSCT as follow-up therapy in ...de novo AML were randomized to a 3 + 7 induction course of daunorubicin (days 1 –3) and cytarabine (days 1–7) with or ... Voir le document complet
5
The impact of HLA-matching on reduced intensity conditioning regimen unrelated donor allogeneic stem cell transplantation for acute myeloid leukemia in patients above 50 years—a report from the EBMT acute leukemia working party
... endpoints of the study were incidences and se- verity of acute and chronic GVHD, NRM, and disease relapse incidence ...(RI). Secondary endpoints included en- graftment, OS, and ...date ... Voir le document complet
15
Post-transplant cyclophosphamide versus antithymocyte globulin in patients with acute myeloid leukemia in first complete remission undergoing allogeneic stem cell transplantation from 10/10 HLA-matched unrelated donors
... estimator to ac- commodate competing risks. For NRM, relapse was the competing risk, and for RI, the competing risk was death without ...relapse. To study acute and chronic GVHD, we ... Voir le document complet
11
Inhibition of ubiquitin-specific protease 7 sensitizes acute myeloid leukemia to chemotherapy
... xenografts in NOD SCID gamma (NSG) mice NOD/LtSz-SCID/ IL-2R γ chain null (NSG) mice were bred at the UMS006 in Toulouse (France) using breeders obtained from Charles ...Committee of the UMS006 and ... Voir le document complet
17
Mitochondrial metabolism supports resistance to IDH mutant inhibitors in acute myeloid leukemia
... SEM of at least five independent experiments. Each point is the mean of three technical ...time of HL60 (different clones) and MOLM14 IDH1 WT and R132H treated or not with doxycycline ...SEM ... Voir le document complet
35
Reduced-toxicity conditioning prior to allogeneic stem cell transplantation improves outcome in patients with myeloid malignancies
... because of an impaired graft-versus-leukemia ...risk of GVHD and non-relapse mortal- ity because of their ages and comorbidities, the use of rabbit anti-thymoglobulin was of ... Voir le document complet
8
Impact of gene mutations on treatment response and prognosis of acute myeloid leukemia secondary to myeloproliferative neoplasms
... used in eligible patients but the response rate is low, toxicity and mortality high with poor long term results 5 ...limit for improving treatment results is that MPN-AML are generally excluded from large ... Voir le document complet
30
View of Specific pulmonary involvement in acute myeloid leukemia: from diagnosis to treatment
... Dans une étude rétrospective portant sur 20 patients atteints de LAM5 et admis en réanimation pour une IRA secondaire à une leucostase pulmonaire ou une infiltration pulmonaire leu- cémi[r] ... Voir le document complet
8
Treatment outcome in infant acute lymphoblastic leukemia
... paper of Do¨rdelmann et al 1 on prednisone (PDN) response as the strongest predictor value of outcome in infant acute lymphoblastic leukemia ...years of age, were ... Voir le document complet
3
Metabolic stress controls mutant p53 R248Q stability in acute myeloid leukemia cells
... responsible for the effective elimination of R248Q. The use of DCA and 17-AAG allowed us to determine the alternative types of the autophagy pathway engaged to degrade R248Q ... Voir le document complet
38
Impact of physicians' characteristics on decision making in elderly acute myeloid leukemia
... responded to the survey, the median age was 42 years old [inter-quartile range (IQR): 32-52], 54% were male, ...worked in academic center, 78% were Hematologists, 61% were involved in AML care ... Voir le document complet
2
Clinical practice recommendation on hematopoietic stem cell transplantation for acute myeloid leukemia patients with FLT3internal tandem duplication: A position statement from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation
... Marrow Transplantation Program, Department of Internal Medicine, American University of Beirut Medical Center, Beirut, Lebanon; 2 Department of Anatomy, Cell Biology, and Physiological ... Voir le document complet
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