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[PDF] Top 20 SIV Infection and the HIV Proteins Tat and Nef Induce Senescence in Adipose Tissue and Human Adipose Stem Cells, Resulting in Adipocyte Dysfunction

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SIV Infection and the HIV Proteins Tat and Nef Induce Senescence in Adipose Tissue and Human Adipose Stem Cells, Resulting in Adipocyte Dysfunction

SIV Infection and the HIV Proteins Tat and Nef Induce Senescence in Adipose Tissue and Human Adipose Stem Cells, Resulting in Adipocyte Dysfunction

... by adipose tissue senescence, inflammation, and fibrosis, with trunk fat ...Aging HIV-infected patients have a higher risk of trunk fat accumulation than uninfected ... Voir le document complet

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en fr Capacity of HIV proteins Tat and Nef and HIV protease inhibitors to induce bone marrow mesenchymal stem cells senescence and to inhibit osteoblastic differentiation Capacité des protéines du VIH Tat et Nef et des inhibiteurs de la protéase virale à induire une sénescence des cellules souches mésenchymateuses de la moelle osseuse et à inhiber leur différenciation ostéoblastique

... conditions, the balance between osteoclast- mediated bone resorption and osteoblast-mediated bone deposition controls bone ...mesenchymal stem cells (MSCs) are pluripotent precursors, capable ... Voir le document complet

171

The HIV proteins Tat and Nef promote human bone marrow mesenchymal stem cell senescence and alter osteoblastic differentiation

The HIV proteins Tat and Nef promote human bone marrow mesenchymal stem cell senescence and alter osteoblastic differentiation

... turnover and bone mineral density (BMD), bone marrow (BM) mesenchymal stem cells (MSCs) are constantly recruited and subsequently differentiated into osteo- ...blasts. HIV-infected ... Voir le document complet

14

Studies of the enzymes that convert steroid hormones in the human adipose tissue

Studies of the enzymes that convert steroid hormones in the human adipose tissue

... of the critical determinants of elevated cardiometabolic risk or the metabolic syndrome is adipose tissue function impairments, which include adipocyte hypertrophy, impaired ... Voir le document complet

276

Intradermal injection of human adipose-derived stem cells accelerates skin wound healing in nude mice

Intradermal injection of human adipose-derived stem cells accelerates skin wound healing in nude mice

... ASC: Adipose-derived stem cells; BMP2: Bone morphogenetic protein 2; CD: Cluster of differentiation; DAB: 3,3 ′- Diaminobenzidine; DMEM: Dulbecco ’s modified Eagle’s medium; DMSO: Dimethyl sulfoxide; ... Voir le document complet

12

Adipose-Derived Mesenchymal Stem Cells in Autoimmune Disorders: State of the Art and Perspectives for Systemic Sclerosis

Adipose-Derived Mesenchymal Stem Cells in Autoimmune Disorders: State of the Art and Perspectives for Systemic Sclerosis

... of human mesenchymal stromal cells: occurrence of aneuploidy without ...(2007) Human bone marrow derived mesenchymal stem cells do not undergo transformation after long-term in ... Voir le document complet

66

Accelerated immune senescence in HIV infection

Accelerated immune senescence in HIV infection

... Aim The prospect that immune activation or inflammation may be directly related to the increased incidence in HIV infected donors of manifestations that are reminis- cent of the ... Voir le document complet

2

Statin therapy modulates thickness and inflammatory profile of human epicardial adipose tissue

Statin therapy modulates thickness and inflammatory profile of human epicardial adipose tissue

... statins. In this population, we observed that statin therapy was a signi ficant predictor of EAT thickness, when added to a clinical model including age, male sex, BMI, hypertension, diabetes, dyslipidaemia ... Voir le document complet

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Regulation of lipogenesis in human adipose tissue: effect of metabolic stress, dietary intervention and aging

Regulation of lipogenesis in human adipose tissue: effect of metabolic stress, dietary intervention and aging

... function, and lipid parameters as bari- atric surgery when the same reduction of body weight and fat mass is achieved ...of the positive effects of severe calorie restriction are observed ... Voir le document complet

160

Regulation of human adipose tissue gene expression in relation to obesity and insulin resistance

Regulation of human adipose tissue gene expression in relation to obesity and insulin resistance

... accumulating in muscle could play a causative role in IR, via activation of PKC and serine/threonine kinases that inhibit insulin signaling ...metabolism in skeletal muscle which exerts high ... Voir le document complet

214

Long noncoding RNA repertoire in chicken liver and adipose tissue

Long noncoding RNA repertoire in chicken liver and adipose tissue

... study, the top 10 and 25% most highly expressed genes represent 34 and 96% of the reads, respectively, in the liver, and 16 and 90% in the ... Voir le document complet

18

Metabolic complications affecting adipose tissue, lipid and glucose metabolism associated with HIV antiretroviral treatment

Metabolic complications affecting adipose tissue, lipid and glucose metabolism associated with HIV antiretroviral treatment

... alterations in body fat repartition, even if the drugs have been stopped years ...distribution and dyslipidemia than age-paired subjects from the general population, even if their BMI is lower ... Voir le document complet

35

Limelight on two HIV/SIV accessory proteins in macrophage infection: is Vpx overshadowing Vpr?

Limelight on two HIV/SIV accessory proteins in macrophage infection: is Vpx overshadowing Vpr?

... of the above paradox, the underlying mecha- nism of Vpr-mediated G2 arrest has been searched for during many ...years. In 2007, these efforts finally bore fruit; when several studies, including ours, ... Voir le document complet

13

Encapsulation of Adipose-Derived Mesenchymal Stem Cells in Calcium Alginate Maintains Clonogenicity and Enhances their Secretory Profile

Encapsulation of Adipose-Derived Mesenchymal Stem Cells in Calcium Alginate Maintains Clonogenicity and Enhances their Secretory Profile

... Concerning the clinical implications of cellular escape, most clinical trials on allogeneic ASCs report few side effects directly linked to cell ...Indeed, in a study on lateral epicondylosis, the ... Voir le document complet

19

In vitro and in vivo impairment of alpha2-adrenergic receptor-dependent antilipolysis by fatty acids in human adipose tissue.

In vitro and in vivo impairment of alpha2-adrenergic receptor-dependent antilipolysis by fatty acids in human adipose tissue.

... action in human fat cells in vitro, was the only agent allowed by the ethical committee for use in microdialysis assays in ...humans. The two perfusate ... Voir le document complet

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Adipose-Derived Stem Cells from Systemic Sclerosis Patients Maintain Pro-Angiogenic and Antifibrotic Paracrine Effects In Vitro

Adipose-Derived Stem Cells from Systemic Sclerosis Patients Maintain Pro-Angiogenic and Antifibrotic Paracrine Effects In Vitro

... result in constitutive activation of fibroblasts and fibrosis affecting skin and multiple ...organs. The interaction of these three processes results in a polymorphous spectrum of ... Voir le document complet

18

Adipose Tissue and Endocrine-Disrupting Chemicals: Does Sex Matter?

Adipose Tissue and Endocrine-Disrupting Chemicals: Does Sex Matter?

... low-flammability and high thermal conductivity properties. The adverse metabolic effects of PCBs may also be mediated by the interaction with estrogen and thyroid signaling pathways, ... Voir le document complet

41

Immune cell-derived cytokines contribute to obesity-related inflammation, fibrogenesis and metabolic deregulation in human adipose tissue

Immune cell-derived cytokines contribute to obesity-related inflammation, fibrogenesis and metabolic deregulation in human adipose tissue

... 1,2,3 Adipose tissue contains a variety of immune cells, which vary in abundance and phenotype with ...obesity. The contribution of immune cell-derived factors to inflammatory, ... Voir le document complet

12

Arachidonic acid and prostacyclin signaling promote adipose tissue development: a human health concern?

Arachidonic acid and prostacyclin signaling promote adipose tissue development: a human health concern?

... extensive adipocyte differentiation, we compared cyclic AMP production after a very short exposure of preadipocytes to concentrations of the various long-chain fatty acids (Table ...15-fold in 5 min ... Voir le document complet

10

Comparison between Stromal Vascular Fraction and Adipose Mesenchymal Stem Cells in Remodeling Hypertrophic Scars

Comparison between Stromal Vascular Fraction and Adipose Mesenchymal Stem Cells in Remodeling Hypertrophic Scars

... consist in standard procedures for wound management to attenuate excessive ...efficacy and emerging therapies are evaluating the use of recom- binant TGF β3 or anti-TGFβ1 antibodies [ 2 ...be ... Voir le document complet

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