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[PDF] Top 20 Induction of systemic oxidative stress leads to brain oedema in portacaval shunted rats

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Induction of systemic oxidative stress leads to brain oedema in portacaval shunted rats

Induction of systemic oxidative stress leads to brain oedema in portacaval shunted rats

... aim of this study was to induce oxidative stress in hyperammonaemic PCA rats by targeting and diminishing the antioxidant GSH, a tripeptide formed of glutamate, cysteine ... Voir le document complet

10

Oxidative stress: a systemic factor implicated in the pathogenesis of hepatic encephalopathy

Oxidative stress: a systemic factor implicated in the pathogenesis of hepatic encephalopathy

... and oxidative stress in the pathogenesis of HE is ...complex. In rats with acute liver failure (induced by hepatic devascularization), the development of brain ... Voir le document complet

5

Systemic oxidative stress is implicated in the pathogenesis of brain edema in rats with chronic liver failure

Systemic oxidative stress is implicated in the pathogenesis of brain edema in rats with chronic liver failure

... failure leads to hyperammonemia, a central component in the pathogenesis of hepatic encephalopathy (HE); however, a correlation between blood ammonia levels and HE severity remains ...believed ... Voir le document complet

16

Mitochondrial oxidative stress in obesity: role of the mineralocorticoid receptor

Mitochondrial oxidative stress in obesity: role of the mineralocorticoid receptor

... addressed to A Nguyen Dinh Cat: ...equally to this work) Abstract Obesity is a multifaceted, chronic, low-grade inflammation disease characterized by excess accumulation of dysfunctional adipose ... Voir le document complet

18

Induction of mucosal immunity through systemic immunization: phantom or reality?

Induction of mucosal immunity through systemic immunization: phantom or reality?

... s yst emi c) immune responses that accord prot ection aga inst specifi c mucosal pat hogens. Increasi ng evidence from experi ment al vaccine and anim al m odel studi es suggest t hat under som e ci rcumst ances (anti ... Voir le document complet

44

Cooperativity between integrin activation and mechanical stress leads to integrin clustering

Cooperativity between integrin activation and mechanical stress leads to integrin clustering

... field to mimic the role of talin regulating integrin binding to the extracel- lular ...Due to the competition between the stress and the allo- steric activation, talin concentration is ... Voir le document complet

11

Oxidative Stress in NAFLD: Role of Nutrients and Food Contaminants

Oxidative Stress in NAFLD: Role of Nutrients and Food Contaminants

... expression of metabolic syndrome and its comorbidities that comprise, among others, obesity and ...spectrum of clinical ...accumulation of fat in hepatocytes, to non-alcoholic ... Voir le document complet

65

Cooperativity between Integrin Activation and Mechanical Stress Leads to Integrin Clustering.

Cooperativity between Integrin Activation and Mechanical Stress Leads to Integrin Clustering.

... involved in crucial cellular biological functions such as migration, adhesion and ...modulation of integrin affinity towards their extracellular ligands by cytoplasmic proteins (inside-out signaling) these ... Voir le document complet

37

Enhanced susceptibility of T lymphocytes to oxidative stress in the absence of the cellular prion protein.

Enhanced susceptibility of T lymphocytes to oxidative stress in the absence of the cellular prion protein.

... contribute to the preservation of the redox homeostasis. Effect of a physiologic oxidative stress on mice In order to extend our in vitro observations to an ... Voir le document complet

23

Effect of portacaval anastomosis on glutamine synthetase protein and gene expression in brain, liver and skeletal muscle

Effect of portacaval anastomosis on glutamine synthetase protein and gene expression in brain, liver and skeletal muscle

... addition to resulting in seriously compromised capacity for ammonia removal, a modest loss of GS activity in brain following PCA could have serious consequences for glutamatergic ... Voir le document complet

7

Changes in Brain MicroRNAs Contribute to Cholinergic Stress Reactions

Changes in Brain MicroRNAs Contribute to Cholinergic Stress Reactions

... psychological stress is known to induce prominent changes in neuronal activity and gene regulation across multiple brain regions (McEwen 2007 ...chronic stress both lead to the ... Voir le document complet

10

Chronic depletion of gonadal testosterone leads to blood–brain barrier dysfunction and inflammation in male mice

Chronic depletion of gonadal testosterone leads to blood–brain barrier dysfunction and inflammation in male mice

... was of great interest that the supplementation of testosterone to castrated mice restored the impermeability of BBB and the integrity of the capillary endothelial TJ, and suppressed ... Voir le document complet

35

Low replication stress leads to specific replication timing advances associated to chromatin remodelling in cancer cells

Low replication stress leads to specific replication timing advances associated to chromatin remodelling in cancer cells

... switches in human cells can be linked to developmental genes expression (3, 13, 54, ...if, in our experimental condition, aphidicolin has a global impact on gene expression and if this could be ... Voir le document complet

30

TLR7 stimulation in human plasmacytoid dendritic cells leads to the induction of early IFN-inducible genes in the absence of type I IFN.

TLR7 stimulation in human plasmacytoid dendritic cells leads to the induction of early IFN-inducible genes in the absence of type I IFN.

... Phosphorylation of STAT1 in response to TLR7 triggering depends on the PI3K-p38MAPK pathway Expression of IFN-inducible genes is regulated by the transcription factor IFN stimulated gene ... Voir le document complet

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en fr Role of the kinase MK2 in hepatobiliary tumor resistance to oxidative stress Rôle de la kinase MK2 dans la résistance au stress oxydatif des tumeurs hépatobiliaires

... Target of Rapamycin), des voies Ras/Raf, de la voie de réponse au stress oxydatif Nrf2 (Nuclear Factor Erythroid-derived-2-Like 2)/Keap1 (Kelch-like ECH-associated protein 1) et de la voie JAK/STAT (Janus ... Voir le document complet

149

Systemic scAAV9 variant mediates brain transduction in newborn rhesus macaques

Systemic scAAV9 variant mediates brain transduction in newborn rhesus macaques

... found in all analyzed regions, including the cortex, striatum, globus pallidus, thalamus, midbrain, hippocampus and cerebellum ...numerous in regions known to undergo profound post-natal maturation, ... Voir le document complet

4

Oxidative and Anti-Oxidative Stress Markers in Chronic Glaucoma: A Systematic Review and Meta-Analysis

Oxidative and Anti-Oxidative Stress Markers in Chronic Glaucoma: A Systematic Review and Meta-Analysis

... Type of glaucoma and clinical application Among the few studies comparing the levels of oxidative or antioxidative stress markers between the different types of glaucoma [ 35 , 36 , 38 ... Voir le document complet

20

Inhibition of xanthine oxidase reduces hyperglycemia-induced oxidative stress and improves mitochondrial alterations in skeletal muscle of diabetic mice.: xanthine oxidase-induced muscle oxidative stress

Inhibition of xanthine oxidase reduces hyperglycemia-induced oxidative stress and improves mitochondrial alterations in skeletal muscle of diabetic mice.: xanthine oxidase-induced muscle oxidative stress

... glucose-induced oxidative stress in skeletal muscle remain to be ...involved in the production of ROS into muscle, including complexes I and III of the electron transport ... Voir le document complet

45

Oxidative stress response: a proteomic view.

Oxidative stress response: a proteomic view.

... other oxidative stress-related modifications, such as conjugation with 4 hydroxynonenal [43], which is a by-product of the oxidative degradation of unsaturated fatty acids While the ... Voir le document complet

22

Vulnerability to stress consequences induced by repeated social defeat in rats: Contribution of the angiotensin II type 1 receptor in cardiovascular alterations associated to low brain derived neurotrophic factor

Vulnerability to stress consequences induced by repeated social defeat in rats: Contribution of the angiotensin II type 1 receptor in cardiovascular alterations associated to low brain derived neurotrophic factor

... social stress, rats become vulnerable to depression, and this state is characterized by persistent low blood levels of brain-derived neurotrophic factor ...aim of this study was ... Voir le document complet

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