[PDF] Top 20 Increased CD127 expression on activated FOXP3+CD4+ regulatory T cells.
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Increased CD127 expression on activated FOXP3+CD4+ regulatory T cells.
... expressed CD127 in a model of acute skin inflammation Although adoptive transfer is a useful model to study Treg activation and suppressive capacity in vivo , it requires transfer into empty hosts, which may ... Voir le document complet
15
Mesenchymal stem cells generate a CD4+CD25+Foxp3+ regulatory T cell population during the differentiation process of Th1 and Th17 cells.
... stem cells (MSCs) are multipotent stromal cells characterized by their ability to differentiate into cells from mesodermal tissue making them an interest- ing cell source for application in ... Voir le document complet
13
Human and Mouse CD8+CD25+FOXP3+ Regulatory T Cells at Steady State and during Interleukin-2 Therapy
... and FOXP3 expression in mice Fresh total cells from the respective tissues were directly stained with the following monoclonal antibodies (mAbs) at prede- termined optimal dilutions for 20 min at ... Voir le document complet
11
en fr CD4+ FOXP3+ Regulatory T celles Homeostasis : role of interleukin-7 and implication in HIV infection pathophysiology L’homéostasie des cellules CD4+ FOXP3+ T régulatrices : rôle de l'interleukine-7 et implication dans la physiopathologie de l'infection par le VIH
... low CD127 expression at murine Treg ...that CD4+FOXP3+CD25high cells express lower levels of CD127 than the FOXP3- counterpart (Cox et ...that FOXP3 ... Voir le document complet
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Inhibition of the JAK/STAT Signaling Pathway in Regulatory T Cells Reveals a Very Dynamic Regulation of Foxp3 Expression
... Reduced Foxp3 by JAK/STAT inhibitors is independent of cell death. (a) CD4 + GFP + T cells sorted from Foxp3-GFP transgenic mice were stimulated with anti-CD3/CD28 beads for 8 days and treated ... Voir le document complet
17
Treatment of experimental autoimmune encephalomyelitis with engineered bi-specific Foxp3+ regulatory CD4+ T cells.
... Autoreactive Tregs are more efficient at controlling organ-specific autoimmune diseases than polyclonal Tregs and have therefore at- tracted a lot of attention [ 20 , 50 ]. Strategies have been developed to either ... Voir le document complet
15
CD161 intermediate expression defines a novel activated, inflammatory and pathogenic subset of CD8+ T cells involved in multiple sclerosis
... these cells are recruited and enriched in the CNS of MS subjects where they locally and specifically secrete ...an increased effector and transmigration pattern of these cells in MS patients compared ... Voir le document complet
2
Regulatory T cells in solid organ transplantation
... Treg cells better suppress the alloreactive effector T-cell response than polyclonal Treg ...Treg cells in their trials (NCT01624077 and ...Treg cells (CD4 + CD25 + CD127 lo ) with ... Voir le document complet
16
Distinct Protein Expression Networks are Activated in Microglia Cells after Stimulation with IFN-γ and IL-4
... CHME-5 cells stimulated with IFN-γ and IL-4 activate an M1-like and M2-like polarization status as confirmed by the expression of major markers such as CD40, IL-6, CD73, IL-10, and ...gene expression ... Voir le document complet
16
High circulating CD4+CD25[hi]FOXP3+ T cell subpopulation early after lung transplantation is associated with development of BOS
... The purpose of this study was to assess whether the peripheral blood T- lymphocyte profile could predict BOS in lung transplant recipients. An in-depth profiling of CD4 and CD8 T cells was prospectively ... Voir le document complet
2
Expression Map of the Human Exome in CD34+ Cells and Blood Cells: Increased Alternative Splicing in Cell Motility and Immune Response Genes.
... CD34+ cells (figure 1C), confirming microarray ...validated expression of DPPA4 in two human embryonic stem cell (hESC) cell lines, HUES1 and one of our laboratory derived cell line, ...HSPC cells ... Voir le document complet
12
Regulatory activity of azabisphosphonate-capped dendrimers on human CD4+ T cell proliferation enhances ex-vivo expansion of NK cells from PBMCs for immunotherapy
... NK cells are generally divided in two subsets that differ in their anatomic distribution, cytotoxic potential and ability to proliferate and produce cytokines ...NK cells initially-obtained their name due ... Voir le document complet
14
Expression of Viral Antigen by the Liver Leads to Chronic Infection Through the Generation of Regulatory T Cells
... Intracellular FoxP3 staining was performed using PE-coupled anti-mouse/rat FoxP3 anti- body (clone FJK-16s) and fixation/permeabilization buffer optimized for staining of mouse cells with FJK-16s ... Voir le document complet
18
OA031-05. HIV escape from natural killer cytotoxicity: Nef inhibits NKp44L expression on HIV-infected CD4+ T cells
... surface expression on CD4 ...tious cells, which over-expressed NKp44L, and the capac- ity for a long-term viral persistence, by the down modulation of NKp44L cell-surface translocation through Nef ... Voir le document complet
2
CD4 ligation excludes the Carma1-Bcl10-MALT1 complex from GM1-positive membrane rafts in CD3/CD28 activated T cells.
... 1 mg/ml enzyme inhibitors) (complete EDTA-free mixture of anti-proteases; Roche) for 30 min. Cell lysates were mixed with an equal volume of 80% sucrose in TNE, overlaid with 6.5 ml of 30% and 3.5 ml of 5% sucrose in ... Voir le document complet
29
Regulatory T cells fulfil their promise ?
... T cells are included in the donor graft, graft-versus-host disease (GVHD) results, a life-threatening complication consisting of the destruction of recipient organs by donor T ...T cells are depleted prior ... Voir le document complet
2
Aire and Foxp3 expression in a particular microenvironment for T-cell differentiation
... purified CD4+ T cells were layered on slides by sed- imentation, then fixed with cold methanol for 7 min and cold methanol/acetone (50: 50) for 3 ...antimouse Foxp3 antibody (10 g/ml; Abcam, ... Voir le document complet
10
Flavanone metabolites decrease monocyte adhesion to TNF-a-activated endothelial cells by modulating expression of atherosclerosis-related genes.
... endothelial cells to flavanones, agly- cones or to their metabolites resulted in changes in expression of ...gene expression profiles revealed a specific pattern of gene expression in HUVEC ... Voir le document complet
12
Enteric alpha-synuclein expression is increased in Crohn’s disease
... IBD and sharing overlapping symptoms and complications, UC and CD are two different disorders from a pathophysio- logical point of view. While CD is primarily associated with T-helper type 1 immune responses, UC ... Voir le document complet
4
Characterizing antigen-specific CD4⁺ T cells using HLA-DR oligomers
... 2000). Cells such as macrophages, neutrophils and monocytes attack pathogens by endocytic and phagocytic mechanisms triggered through cell-surface receptors which are not well understood but are a hot topic of ... Voir le document complet
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