Haut PDF In silico analysis of mitochondrial proteins
In silico analysis of mitochondrial proteins
... Orthologs of subfamilies were identified by a two-round procedure combining BLAST search with phylogenetic ...phylogenetic analysis. The difference between round one and two was the set of seed ...
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Mitochondrial DNA analysis of the geographic structure of Indian scad mackerel in the Indo-Malay archipelago
... We are grateful to P.H. Barber for helpful advice and corrections on this manuscript; to V. Castric, C. Poux, A. Rohfritsch, and Suprapto for help with laboratory work; to R. Andamari, S.B. Atmaja, A.S. Cabanban, G. ...
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In Silico Survey of the Mitochondrial Protein Uptake and Maturation Systems in the Brown Alga Ectocarpus siliculosus
... annotation of mitochondrial proteins Mitochondrial proteins encoded by the Ectocarpus nuclear genome were identified using several different ...First, proteins with N-terminal ...
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RNA interference screen reveals a high proportion of mitochondrial proteins essential for correct cell cycle progress in Trypanosoma brucei
... definition of cell cycle defects At day 5 post-induction, cells were fixed in 4% parafor- maldehyde and stained with 4′,6-diamidino2-phenylindole (DAPI), air-dried on microscope immunofluorescence slides, ...
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Comprehensive functional analysis of large lists of genes and proteins
... used in research, often integrated with new data generated by ...type of analyses to select candidate markers are more and more ...lists of genes and proteins revealing new biological insights ...
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Discrete analysis of camelid variable domains: sequences, structures, and in-silico structure prediction
... conformational analysis Secondary structures were assigned with the most widely used algorithm, namely DSSP (CMBI version 2000) with default parameters (Kabsch et Sander ...composed of 16 local prototypes ( ...
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Metabolomics and in-silico analysis reveal critical energy deregulations in animal models of Parkinson’s disease
... In this work, we have studied the effect of PD-related perturbations on brain cells ...measured in brain tissue from Parkin KO (knockout) mice, as well as in brain tissue exposed to the ...
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In silico analysis of the binding of anthelmintics to Caenorhabditis elegansP-glycoprotein 1.
... used in animals and humans against parasite nematodes, but their therapeutic success is compromised by the spread of ML ...overexpressed in ML-resistant nematodes, supporting a role for some drug ...
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Mitochondrial proteomics : analysis of a whole mitochondrial extract with two-dimensional electrophoresis.
... Dysfunction of mitochondria can lead to several disorders of varied severity, ranging from intolerance to an intense effort to perinataly fatal ...Progressive mitochondrial dysfunction has also been ...
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Ancient and conserved functional interplay between Bcl-2 family proteins in the mitochondrial pathway of apoptosis
... ability of recombinant trBcl-2L1 and trBcl-2L2 to engage peptides spanning the BH3 motif of trBak and trBax using isothermal titration calorimetry (ITC) ...Our analysis revealed that trBcl-2L1 only ...
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In silico local structure approach: A case study on Outer Membrane Proteins.
... approach of HMM comparison [47] to further analyze the differences between SA20-OMP and ...This analysis is based on the likelihood of the structures under three different alphabets: SA20-OMP, ...
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Systematic Identification of Mitochondrial Proteins by LC−MS/MS
... the analysis of one digested gel slice and stated in particular that 40% of the spectra were automatically identified, whereas 41% were ...unusable. In an attempt to improve the quality ...
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Transcriptome analysis reveals link between proteasomal and mitochondrial pathways in Parkinson's disease.
... up-regulated in the PD, with none passing the multiple comparisons test. Only seven of these were up-regulated in both the SNm and SN1 (supplemental Table 1 in ...transcribed proteins ...
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Chemical targeting of NEET proteins reveals their function in mitochondrial morphodynamics
... For mitochondrial and cytosolic fraction preparations, after treatment HeLa cells were washed twice and gently scraped in cold ...re-suspended in M buffer (440 mM mannitol, 140mM sucrose, 40mM HEPES, ...
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An in-silico analysis of information sharing systems for adaptable resources management: A case study of oyster farmers
... consequences of consumption (Raihanian Mashhadi and Behdad, 2018), or in financial markets (Schmitt and Westerhoff, ...strength of such models (An, ...convergence of beliefs, heterogeneity has ...
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Advances in the quantification of mitochondrial function in primary human immune cells through extracellular flux analysis
... and mitochondrial perturbation concentrations determined herein are consistent with published work that showed XF analysis requires 75,000–600,000/ well of freshly isolated human peripheral blood ...
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Connecting mitochondrial dynamics and life-or-death events via Bcl-2 family proteins
... abnormal mitochondrial distribution and trafficking have been described in many neurodegenerative disease models such as Alzheimer’s disease (Pigino et ...differences in the trafficking machinery ...
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Evolutionary relationships and expression analysis of EUL domain proteins in rice (Oryza sativa)
... members of the different lectin families [Agaricus bisporus agglu- tinin (ABA), ...search. In addition the MSU database (Kawahara et ...lectin)] of the different lectin ...presence of ...
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In Situ Analysis of Weakly Bound Proteins Reveals Molecular Basis of Soft Corona Formation
... concentration of 50 mM phosphate buffer was required to maintain the solution at pH 7 under our experimental condi- ...Because of the buffering effect of SNPs, a smaller con- centration of ...
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Kernel methods for in silico chemogenomics
... list of known compounds for each ...categories of compounds are defined to indicate the type of interaction between each target and each ...types of interactions on a given target might ...
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