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[PDF] Top 20 In quest for leukemia initiating cells in AML

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In quest for leukemia initiating cells in AML

In quest for leukemia initiating cells in AML

... stem cells (LSC), also referred as leukemia-initiating cells (LIC), represent a rare subpopulation of leukemic cells that possess stem cell properties distinct from bulk leukemic ... Voir le document complet

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The stem cell mobilizing capacity of patients with acute myeloid leukemia in complete remission correlates with relapse risk: results of the EORTC-GIMEMA AML-10 trial

The stem cell mobilizing capacity of patients with acute myeloid leukemia in complete remission correlates with relapse risk: results of the EORTC-GIMEMA AML-10 trial

... + cells (ⱖ7 x 10 6 /kg) in a single apheresis had the highest relapse incidence and the shortest disease-free sur- vival, whereas patients with the lowest number of CD34 + cells (⬍1 x 10 6 /kg) ... Voir le document complet

8

Cytogenetic clonal heterogeneity is not an independent prognosis factor in 15-60-year-old AML patients: results on 1291 patients included in the EORTC/GIMEMA AML-10 and AML-12 trials.

Cytogenetic clonal heterogeneity is not an independent prognosis factor in 15-60-year-old AML patients: results on 1291 patients included in the EORTC/GIMEMA AML-10 and AML-12 trials.

... (OS) in younger acute myeloid leukemia (AML) patients has improved in the recent decades, disease relapse remains the first cause of death in younger pa- tients with AML [ 1 – 6 ... Voir le document complet

11

Exploiting metabolic vulnerabilities for personalized therapy in acute myeloid leukemia

Exploiting metabolic vulnerabilities for personalized therapy in acute myeloid leukemia

... CPT1a in AML increases free fatty acids and glucose uptake only in bone marrow adipocyte co- cultures, allowing blasts to preserve their viability [ 208 ...balance in whole organisms and will ... Voir le document complet

18

NKp46 expression on NK cells as a prognostic and predictive biomarker for response to allo-SCT in patients with AML

NKp46 expression on NK cells as a prognostic and predictive biomarker for response to allo-SCT in patients with AML

... Allo-SCT; AML; NCR; NK; NKp46 Introduction Acute myeloid leukemia (AML) is a hematologic disorder char- acterized by variable responsiveness to ...(CR) in most patients; however, relapse ... Voir le document complet

11

Activated Allogeneic NK Cells Preferentially Kill Poor Prognosis B-Cell Chronic Lymphocytic Leukemia Cells

Activated Allogeneic NK Cells Preferentially Kill Poor Prognosis B-Cell Chronic Lymphocytic Leukemia Cells

... NK cells have been shown to be effective in the treat- ment of poor prognosis acute myeloid and lymphoid leukemia (AML and ALL) ( 34 , 37 – 42 ...NK cells also recognize B-CLL ... Voir le document complet

12

Core Circadian Clock Genes Regulate Leukemia Stem Cells in AML

Core Circadian Clock Genes Regulate Leukemia Stem Cells in AML

... enriched for LSCs and are suitable for in vivo screening (Miller et ...examined in such an in vivo screen, we first identified candidate TFs on the basis of gene expression (Bullinger ... Voir le document complet

27

Dexamethasone in hyperleukocytic acute myeloid leukemia

Dexamethasone in hyperleukocytic acute myeloid leukemia

... A) Leukemia long-term culture initiating cell (L-LTC-IC) frequency in acute myeloid leukemia (AML) samples upon dexamethasone treatment (#38 to 49, Online Supplementary Table ... Voir le document complet

12

Clofarabine in combination with a standard remission induction regimen in patients 18-60 years old previously untreated intermediate an bad risk actue myelogenous leukemia (AML) or high risk myelodysplasia (MDS): combined phase I/II results of the EORTC/G

Clofarabine in combination with a standard remission induction regimen in patients 18-60 years old previously untreated intermediate an bad risk actue myelogenous leukemia (AML) or high risk myelodysplasia (MDS): combined phase I/II results of the EORTC/Gimema AML-14A trial

... Clofarabine in Combination with a Standard Remission Induction Regimen in Patients 18-60 Years Old with Previously Untreated Intermediate and Bad Risk Acute Myelogenous Leukemia (AML) or High ... Voir le document complet

3

Quest for plasma biomarkers for beef tenderness

Quest for plasma biomarkers for beef tenderness

... archive for the deposit and dissemination of sci- entific research documents, whether they are pub- lished or ...institutions in France or abroad, or from public or private research ... Voir le document complet

2

Efficient Probabilistic Inference in the Quest for Physics Beyond the Standard Model

Efficient Probabilistic Inference in the Quest for Physics Beyond the Standard Model

... simulators in a language-agnostic ...inference in the structured model defined by the simulator code ...technique in particle physics, on a scientifically accurate simulation of the τ (tau) lepton ... Voir le document complet

19

The quest for epigenetic regulation underlying unisexual flower development in Cucumis melo

The quest for epigenetic regulation underlying unisexual flower development in Cucumis melo

... enrichment for transporter activity, catalytic activity, oxidoreductase activity and interestingly, for transcrip- tion factor (TF) activity ...pathways in sex determination in the ... Voir le document complet

18

NG2-expressing glial precursor cells are a new potential oligodendroglioma cell initiating population in N-ethyl-N-nitrosourea-induced gliomagenesis.

NG2-expressing glial precursor cells are a new potential oligodendroglioma cell initiating population in N-ethyl-N-nitrosourea-induced gliomagenesis.

... perspectives for understanding several features of the human ...uniform cells with minimal process formation, regular round nuclei, and arborizing capillary network that stained with collagen IV and IQGAP1 ... Voir le document complet

40

Anime Creativity: Characters and Premises in the Quest for Cool Japan

Anime Creativity: Characters and Premises in the Quest for Cool Japan

... Orientalism, in the ways it represented its objects, also constituted a form of ...Orient” in certain ways was also a means to power over people’s and ...argue in a similar vein that elisions ... Voir le document complet

40

Acute lymphoblastic leukemia in children

Acute lymphoblastic leukemia in children

... Le nombre (n = 13 soit 16,5 %) d’échecs thé- rapeutiques (rechutes et patients réfractaires : plus de 25 % de blastes après l’induction) que nous avons observé est bas mais le taux de “r[r] ... Voir le document complet

7

Bevacizumab potentiates chemotherapeutic effect on T-leukemia/lymphoma cells by direct action on tumor endothelial cells.

Bevacizumab potentiates chemotherapeutic effect on T-leukemia/lymphoma cells by direct action on tumor endothelial cells.

... T cells, is involved in tumor progression in ...progression. In a murine xenograft T- leukemia/lymphoma model, combined bevacizumab (mono- clonal antibody against vascular endothelial ... Voir le document complet

6

Kinetics of Cytotoxic Lymphocytes Reconstitution after Induction Chemotherapy in Elderly AML Patients Reveals Progressive Recovery of Normal Phenotypic and Functional Features in NK Cells

Kinetics of Cytotoxic Lymphocytes Reconstitution after Induction Chemotherapy in Elderly AML Patients Reveals Progressive Recovery of Normal Phenotypic and Functional Features in NK Cells

... alterations in the development of NK cells both at diagnosis and during the treatment, since CT induces ...aplasia. For instance, after HSCT, the population of immature NK cells is prominent ... Voir le document complet

13

Fecal microbiota transplantation in inflammatory bowel disease: the quest for the holy grail

Fecal microbiota transplantation in inflammatory bowel disease: the quest for the holy grail

... therapy in IBD but more studies are needed to define the best indications, optimal timing, frequency, mode of delivery and the optimal donor for each ...player in intestinal homeostasis with ... Voir le document complet

20

Glycoproteomic Analysis of MGL-Binding Proteins on Acute T-Cell Leukemia Cells

Glycoproteomic Analysis of MGL-Binding Proteins on Acute T-Cell Leukemia Cells

... § Institut de Pharmacologie et de Biologie Structurale, Universite ́ de Toulouse, CNRS, UPS, Toulouse 31062, France * S Supporting Information ABSTRACT: C-type lectins are a diverse group of proteins involved in ... Voir le document complet

9

Treatment outcome in infant acute lymphoblastic leukemia

Treatment outcome in infant acute lymphoblastic leukemia

... outcome in infant acute lymphoblastic leukemia ...Children Leukemia Coopera- tive Group-European Organization for Research and Treat- ment of Cancer (CLCG-EORTC) protocol ...defined in ... Voir le document complet

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