[PDF] Top 20 A human gonadal cell model from induced pluripotent stem cells

... obtained from mouse Sertoli cells (TM4 cell line) or derived from human pluripotent carcinoma tissue (NT2d1 cell ...Mouse cell models like TM4 have shown ... Voir le document complet

... bundles from pluripotent stem ...of cell-based therapies. Human ESCs challenged with retinoic acid (RA), epidermal growth factor (EGF), and other growth factors have previously been ... Voir le document complet

... luid-derived induced pluripotent stem ...(AF) cells at 26 weeks of gestation (AFC) were obtained from he Ottawa Hospital (Ottawa, Ontario, Canada) following routine ...obtained ... Voir le document complet

... is a life-threatening condition, each newly discovered drug must pass a well-defined safety screen protocol that comprises extensive testing on the hERG channel ...included a direct ... Voir le document complet

... is a critical modulator of cholesterol ...have a cardio-protective effect and in some cases can lead to familial hypobetalipoproteinemia ...urine-sample-derived human induced ... Voir le document complet

... protected from transposition, this approach enables the inference of transcription factor occupancy at the level of individual functional regulatory ...with a periodicity of about 150–200 bp, corresponding ... Voir le document complet

... protected from transposition, this approach enables the inference of transcription factor occupancy at the level of individual functional regulatory ...with a periodicity of about 150–200 bp, corresponding ... Voir le document complet

... the induced pluripotent stem cell line UHOMi002-A from peripheral blood mononuclear cells of a healthy male donor Mathieu Fieldes, Engi Ahmed, Chloé Bourguignon, ... Voir le document complet

... blood cell generation from human induced pluripotent stem cells: perspectives for transfusion ...by a joint grant from Agence Nationale pour la ... Voir le document complet

... Supplementary figure S1: RNA seq gene expression analysis of SCs marker for single colonies. All values are relative to iPSCs expression levels (dotted horizontal line).[r] ... Voir le document complet

... France A B S T R A C T Congenital myasthenic syndromes (CMS) are a class of inherited disorders affecting the neuromuscular junction, a synapse whose activity is essential for ...COLQ, ... Voir le document complet

... these cells are able to react to inflammatory stimuli; how- ever, most use serum in the culture medium to differentiate GPCs into ...FBS-treated cells. We show that FBS-treated astrocytes, either ... Voir le document complet

... Passive membrane and firing properties of iPSCMNs The present work extends upon previous electrophysiological studies on iPSCMNs ( Karumbayaram et al., 2009 ; Hu et al., 2010 ; Bilican et al., 2012 ; Egawa et al., 2012 ; ... Voir le document complet

... oocytes, from fusion of ESC with somatic cells, or from somatic cells through induction with pluripotency factors (induced PSC, iPSC) [73; ...Embryonic Stem Cells: The ... Voir le document complet

... for Human Genetics, University of Oxford, UK 3 OCDEM, University of Oxford, UK 4 IMS, CNRS UMR 5218, Bordeaux INP, University of Bordeaux, France 5 Oxford NIHR Biomedical Research Centre, Churchill Hospital, ... Voir le document complet

... Feeder cells are frequently used for the early-stage of derivation and culture of human embryonic stem cell (hESC) ...established a conditionally immortalized human foreskin ... Voir le document complet

... to a wide array of neural subtypes using protocols optimized for ESCs ...that human iPSC lines derived using disparate methods ...Remarkably, cell lines derived using non- integrating episomal ... Voir le document complet

... to cell sources, cell culture methods also require new ...Therefore, a number of reports have suggested the use of three-dimensional (3D) cul- ture methods to render hepatocytes more functional ... Voir le document complet

... low cell density (40 cells/mm 2 ), to best model the ability of cells to grow in ...non-contacting cells were observed on most polymer spots after 24 hrs cell culture ...adherent ... Voir le document complet

... from both groups combined with bioinformatics network analysis revealed significant changes in expression of genes related to the regulation of ion channels homeostasis (DLG2, KCNE4, CAMKV and ...for a ... Voir le document complet