Top PDF Globin Gene Expression: Role of Transcription Factors
Globin Gene Expression: Role of Transcription Factors
... restriction of cell fate capacities from hematopoietic stem cells (HSCs) to mature blood ...repression of specific ...combinations of specific transcription factors, which cooperate to ...
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Cell-Cycle Dependence of Transcription Dominates Noise in Gene Expression
... burst of mRNA, is commonly invoked to explain the observed single-cell variability in mRNA numbers [1] of noisy ...beyond gene dosage effects drive much of the observed single-cell variability ...
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Role of transcription factor KLF11 and its diabetes-associated gene variants in pancreatic beta cell function
... a Role in Glucose Signaling in Pancreatic Beta ...inducible expression in exocrine cells, KLF11 mRNA is up-regulated by TGF- in beta cells ...mRNA expression in beta cells (Fig. 1B). KLF11, as a ...
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The functions of Mediator in Candida albicans support a role in shaping species-specific gene expression
... and gene expression data in yeast supports the notion that Mediator is universally required for RNA polymerase II-dependent transcription (reviewed in [12]), and we therefore suggest that Mediator is ...
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Nuclear life of the voltage-gated Cacnb4 subunit and its role in gene transcription regulation.
... direction of the changes in expression levels in differentiated NG108-15 cells was opposite to the changes observed in HEK293 ...a gene may be differently regulated by expression of β 4 ...
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Overexpression of Meloe Gene in Melanomas Is Controlled Both by Specific Transcription Factors and Hypomethylation
... This expression profile does not fit with that of a differentiation antigen, expressed in a specific lineage and totally absent in other tissues, nor with that of a cancer germline antigen normally ...
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The mouse Muc5b mucin gene is transcriptionally regulated by thyroid transcription factor-1 (TTF-1) and GATA-6 transcription factors.: Regulation of Muc5b mucin gene by TTF-1 and GATA factors
... one of the major mucin genes expressed in the respiratory ...TTF-1 expression, a lung-specific transcription factor, was ...regulation of MUC5B expression in the lung are largely ...
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Role of Lmx1a and Lmx1b transcription factors in post-mitotic midbrain dopaminergic neurons
... Plxnc1 expression Transcription factors can positively or negatively regulate the expression of hundreds of ...development of mDA neurons, we performed gene ...
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Towards resolving the transcription factor network controlling myelin gene expression.
... effects of inherited or acquired myelin abnor- malities in diseases such as multiple sclerosis, it plays a critical role in nervous system ...regulation of numerous genes. The complexity of ...
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Ethylene signalling receptors and transcription factors over the grape berry development: gene expression profiling
... and transcription factors across berry development and the impact of one specific inhibitor of ethylene action on their respective mRNA ...integration of the ethylene signalling with ...
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The combined immunodetection of AP-2alpha and YY1 transcription factors is associated with ERBB2 gene overexpression in primary breast tumors.
... ERBB2 gene amplification in 11 cases of breast cancer. All of these had an ERBB2 3+ score in ...out of the 15 ERBB2 3+ cases, 11 were FISH-pos- itive, 2 showed no ERBB2 amplification, 1 was ...
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Real-time feedback control of gene expression
... lack of precision in conventional gene induction systems is a problem for quantitative biology, because understanding the quantitative dynamics of cellular processes requires the ability to apply ...
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Chromosomal profiles of gene expression in Huntington's disease.
... domains of repressed transcription co-exist with sizeable domains of increased ...activity of a large number of transcripts, that has been previously reported (Borovecki et ...samples ...
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Gene expression analysis of flax seed development
... indicative of the distinct seed maturation program that is occurring in the later stages of embryo ...all of the tissues normally present in whole stems (ST), and was enriched for the phloem and ...
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Acute Effects of the Consumption of Passiflora setacea Juice on Metabolic Risk Factors and Gene Expression Profile in Humans
... intake of PS juice kept IL-17A at a basal level and indicated a tendency to decrease TNF-alpha levels (p = ...production of other pro-inflammatory cytokines such as TNF-alpha, IL-1B, and IL-6 [ 44 ], as ...
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Unsupervised Bayesian linear unmixing of gene expression microarrays
... dimensions of the factor loading matrix M and the factor score matrix A depend on the unknown number R of signatures to be ...spaces of different ...ation of the algorithm (see the Appendix ...
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Role of the DHH1 Gene in the Regulation of Monocarboxylic Acids Transporters Expression in Saccharomyces cerevisiae
... analyses of the dhh1 role in metabolic adaptation To highlight the role of Dhh1 in the gene regulation associated with carboxylic acids and non fermentative growth conditions, we ...
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The role of histone variant H2A.Z in the regulation of gene expression in breast cancer cells
... 3C assays Chromatin conformation capture assays were performed essentially as described, 52 with only minor modifications. MDA-MB231 cells were transfected with a scrambled control siRNA ( ÿ ), with H2A.Z SMARTpool siRNA ...
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Control of gene expression by cell size
... microarrays. Expression levels of a gene in the ploidy series are normalized to the mean (set to 0) and the standard deviation (set to ...profile of polyploids resembled stationary phase ...
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Human herpes virus-6 induced changes in the expression and activity of the E2F family transcription factors in human cells
... By using Western blots and electromobility shift assays (EMSA), we compared the expression and DNA-binding activities of the E2F farnily members between the virns-infected and mock-infec[r] ...
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