[PDF] Top 20 Genetic determinants of clinical heterogeneity in sickle cell disease
Has 10000 "Genetic determinants of clinical heterogeneity in sickle cell disease" found on our website. Below are the top 20 most common "Genetic determinants of clinical heterogeneity in sickle cell disease".
Genetic determinants of clinical heterogeneity in sickle cell disease
... Sickle cell disease (SCD) is characterized by extreme clinical heterogeneity: whereas some patients are only mildly affected ...and genetic factors. We wish to further explore ... Voir le document complet
238
Genomic architecture of sickle cell disease clinical variation in children from West Africa : a case-control study design
... studies of peripheral blood isolates confirmed the genetic contribution in gene expression variation somewhat surprisingly since the environmental component of variance should be much higher ... Voir le document complet
290
The Association of CD81 Polymorphisms with Alloimmunization in Sickle Cell Disease
... goal of the present work was to identify the candidate genetic markers predictive of alloimmunization in sickle cell disease ...blood cell (RBC) transfusion is ... Voir le document complet
11
Novel insights into the role of fetal hemoglobin in spleen function, red cell survival and ineffective erythropoiesis in sickle cell disease
... into determinants of spleen injury in sickle cell anemia In this part of the study, 57 SCA infants were included in a comprehensive longitudinal multi- center study ... Voir le document complet
229
Deciphering causal genetic determinants of red blood cell traits
... 6.1.3 Sickle cell disease and malaria susceptibility Reactivation of HbF is still the most promising therapy for ...GWAS of HbF revealed genetic variants in BCL11A, MYB, ... Voir le document complet
287
Red blood cell alloimmunization in sickle cell disease: pathophysiology, risk factors, and transfusion management.
... management of alloimmunization and DHTR in ...aid in developing strategies to prevent and inhibit production of antibodies in transfused patients, and to minimize its life-threatening ... Voir le document complet
38
Effect of N-acetylcysteine on pain in daily life in patients with sickle cell disease: a randomised clinical trial
... sponsors of this study are public or non-profit organizations that support science in ...role in gathering, analysing or interpreting the ...employees of the haematology clinical trial ... Voir le document complet
4
The genetics of red blood cell density, a biomarker of clinical severity in sickle cell disease
... the clinical heterogeneity of SCD, and that erythrocyte dehydration is a typical feature of the disorder, in this thesis, we attempted to identify the genetic factors ... Voir le document complet
101
Added value of speckle tracking in the evaluation of cardiac function in patients with sickle cell disease.
... Evaluation of myocardial deformation in patients with sickle cell disease and preserved ejection fraction using three-dimensional speckle tracking ... Voir le document complet
3
Sickle cell disease and COVID-19: Atypical presentations and favorable outcomes.
... terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly ...healing of his leg ulcer and rapid ... Voir le document complet
4
Analysis of Hemodynamic Changes and Bold Signals of Sickle Cell Disease Patients during Desaturation
... Corresponding Julie Coloigner †, PhD Children's hospital Los Angeles, CA Phone Number: 3235575493 Email: julie.coloigner@gmail.com Will not be published Alternate Email: julie.coloi[r] ... Voir le document complet
5
Determinants of genetic diversity
... combination of demographic fluctuations, genetic hitch‑hiking, mutation rate variation and molecular con‑ straints on ...accumulation of genome‑ wide data from natural populations in a large ... Voir le document complet
13
Added value of speckle tracking in the evaluation of cardiac function in patients with sickle cell disease.
... time of E mitral wave; E 0 , early diastolic mitral annular tissue Doppler velocity; E/A, early peak diastolic velocity of the mitral inflow/late peak diastolic velocity of the mitral inflow; E/ E 0 ... Voir le document complet
3
Genetic determinants associated with cfxA-positive clinical Capnocytophaga isolates
... PCR. In 29/31 isolates, the presence of 966 bp corresponding to the complete sequence of cfxA was detected (27 isolates were E-lactam-resistant but 2 were ...and in silico analysis showed that ... Voir le document complet
9
Beneficial effects of endurance exercise training on skeletal muscle microvasculature in sickle cell disease patients
... Changes in microvascular characteristics after 8 weeks of moderate-intensity endurance exercise training or habitual daily life are presented in Table ...changes in microvascular network ... Voir le document complet
9
Carboxy-terminal fragment of fibroblast growth factor 23 induces heart hypertrophy in sickle cell disease
... In multivariate regression analysis the relationship between LVMI and cFGF23 remained significant after stepwise adjustment for haemoglobin and GFR (Table ...251 of FGF23 in Chinese hamster ovary ... Voir le document complet
12
Modelling T cell proliferation: Dynamics heterogeneity depending on cell differentiation, age, and genetic background
... Vibert, J. and V. Thomas-Vaslin (2017). PLos Comput Biol 13 (3): e1005417. http://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1005417 28 global defective proliferation rates as compared to B6 mice, ... Voir le document complet
56
Survival among children and adults with sickle cell disease in Belgium: Benefit from hydroxyurea treatment
... mortality in Belgium, our analyses provide information on specific outcome according to therapeutic ...decades in adults and ...evidence of safety and efficacy data for HU ...offered in very ... Voir le document complet
6
Histone variants: critical determinants in tumour heterogeneity
... periods of the male genome life. At the time of commitment of male germ cells into meiotic divisions, these variants accumulate and gradually become the major nucleosomal H2A and H2B histone types ... Voir le document complet
10
Development of cellular and gene therapies for b[beta]-Thalassemia and sickle cell disease
... Division of Université de Montréal. The author of this thesis or dissertation has granted a nonexclusive license allowing Université de Montréal to reproduce and publish the document, in part or ... Voir le document complet
340
Sujets connexes