[PDF] Top 20 Gene regulation by voltage-dependent calcium channels.
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Gene regulation by voltage-dependent calcium channels.
... channels are the sole pathways that allow a rapid and localized elevation in Ca 2 + ...occur by the effective recruitment of various cytosolic and/or nuclear signaling pathways whose life-times are of ... Voir le document complet
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Importance of voltage-dependent inactivation in N-type calcium channel regulation by G-proteins.
... channel regulation by G-proteins N-type channel regulation by G-proteins can be described accurately by three parameters: the G-protein inhibition level at the onset of depolarization ... Voir le document complet
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Introducing an alternative biophysical method to analyze direct G protein regulation of voltage-dependent calcium channels.
... of regulation of voltage-dependent calcium channel by G ...protein-inhibited channels inactivate with the same rate than control ...protein regulation: GI , the initial ... Voir le document complet
12
Calredoxin represents a novel type of calcium-dependent sensor-responder connected to redox regulation in the chloroplast
... v5.5 gene models (Joint Genome Institute) merged with mitochondrial and chloroplast protein sequences from NCBI databases ...performed by MaxQuant using a target-decoy ... Voir le document complet
15
Familial hemiplegic migraine type 1 mutations W1684R and V1696I alter G protein-mediated regulation of Ca(V)2.1 voltage-gated calcium channels.
... reduced voltage-dependent inhibition by G proteins of the Ca V ...mutant channels is presently unknown, it is tempting to speculate that differences like this might be related to electrostatic ... Voir le document complet
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Up-regulation of voltage-gated sodium channels by peptides mimicking S4-S5 linkers reveals a variation of the ligand-receptor mechanism
... activation voltage dependence, suggest that peptides are acting on different conformational transitions leading to channel ...channel voltage-dependent gating, implying several conformational ... Voir le document complet
19
Voltage-gated ion channels and gating modifier toxins.
... K channels would then resemble the Na and Ca channels in having an associated subunit with a single transmembrane V V V segment and short intracellular and extracellular ...the voltage-gated ion ... Voir le document complet
17
In vitro differentiation of W8B2 + human cardiac stem cells: gene expression of ionic channels and spontaneous calcium activity
... conductance calcium- activated potassium ...II calcium calmodulin ...Cav: calcium channel, voltage-dependent. Cav1.2: calcium channel, voltage-dependent, L type, ... Voir le document complet
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T-type calcium channels in neuropathic pain
... of voltage gated sodium channels is partially conserved in T- type calcium channels ...bacterial voltage gated sodium channels [97; 98] this knowledge may help guide further ... Voir le document complet
32
Voltage- and cold-dependent gating of single TRPM8 ion channels
... (TRP) channels play critical roles in cell signaling by coupling various environmental factors to changes in membrane potential that modulate calcium ...TRP channels are typically activated in ... Voir le document complet
24
Physiological involvement of presynaptic L-type voltage dependent calcium channels in GABA release of cerebellar molecular layer interneurons
... Tanabe T, Takeshima H, Mikami A, Flockerzi V, Takahashi H, Kangawa K, Kojima M, Matsuo H, Hirose T, Numa S. (1987) Primary structure of the receptor for calcium channel blockers from skeletal muscle. Nature ... Voir le document complet
147
Antibodies against the beta subunit of voltage-dependent calcium channels in Lambert-Eaton myasthenic syndrome
... We have confirmed the usefulness of N- and P/Q- type channel immunoprecipitation assays to detect autoantibodies in LEMS (Fig. 1). Taken together, we found that 80% of the sera had antibodies capable of ... Voir le document complet
10
Nuclear life of the voltage-gated Cacnb4 subunit and its role in gene transcription regulation.
... a gene may be differently regulated by expression of β 4 depending on the cell lines likely reflects the versatility of the protein composition of the β 4 platform in these cell ...4 dependent ... Voir le document complet
16
Inhibition of Cav3.2 T-type Calcium Channels by Its Intracellular I-II Loop
... Voltage-dependent calcium channels (Cav) of the T-type fam- ily ...activated by low threshold membrane depolarization and contribute greatly to neuronal network ...Cav3.2 ... Voir le document complet
11
Voltage-Sensor Probes as efficient tools to screen for new modulators of voltage-gated sodium channels
... ion channels are confined to primary afferent neurons where they likely contribute to the detection and transmission of different kinds of nociceptive ...T-type calcium channel ...replaced by a ... Voir le document complet
2
How do T-type calcium channels control low-threshold exocytosis?
... T-type calcium channels act as a major pathway for calcium entry near the resting mem- brane potential in a wide range of neuronal cell ...T-type channels in the control of vesi- cular ... Voir le document complet
5
Microtubule regulation in mitosis: tubulin phosphorylation by the cyclin-dependent kinase Cdk1.
... phosphorylated by Cdk1 in mitotic cells, but did not preclude the possibility that -tubulin was phosphorylated by another kinase at a site cross-reacting with the P172 ... Voir le document complet
11
Quercetin induces insulin secretion by direct activation of L-type calcium channels in pancreatic beta cells
... indicated by the increase in ERK1/2 phosphor- ylation, and are specific to quercetin, as two other antioxidant compounds (resveratrol and NAC) do not show such ...a calcium- dependent process, and an ... Voir le document complet
13
Development and optimization of a new gene regulation system controlled by nutrition applicable for gene therapy
... Figure 5 : The reversible AARE-Gene system is induced the most in response to diets lacking Isoleucine, Valine or Threonine and can be used for transgene delivery in the liver, pancreas or the brain (A) Process ... Voir le document complet
2
Mutation associated with an autosomal dominant cone-rod dystrophy CORD7 modifies RIM1-mediated modulation of voltage-dependent Ca2+ channels.
... RIM1 R655H -28.13 4.70 * -5.41 0.87 ### 9.92 0.59 0.73 0.02 -18.00 1.56 * -10.84 0.74 *** 1) *P < 0.05, **P < 0.01, ***P < 0.001 versus vector (ANOVA, Fisher's test). 2) # P < 0.05, ## P < 0.01, ### P < ... Voir le document complet
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