[PDF] Top 20 The function of a membrane protein : studies of structure and dynamics by NMR
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The function of a membrane protein : studies of structure and dynamics by NMR
... the ORC1 sample was concentrated to no more than ...(otherwise the higher molecular weight, likely oligomeric peak would appear) and subjected to gel filtration on HiLoad Superdex 200 16/60 prep ... Voir le document complet
240
Structural biology by NMR: structure, dynamics, and interactions.
... experimentalists and theoreticians alike. The study of dynamics at these longer time-scales are centred mostly on relaxation dispersion and RDC ...In the presence of ... Voir le document complet
8
Molecular dynamics studies of the nucleoprotein of influenza A virus: role of the protein flexibility in RNA binding
... structure of the H1N1 protein to which the missing regions have been ...study protein dynamics, especially of flexible regions unsolved by X-ray ... Voir le document complet
10
Nanodomain Clustering of the Plant Protein Remorin by Solid-State NMR
... Structural studies of the mechanisms behind protein-lipid nanodomain formation and assembly at the atomic level remain scarce, mostly relying on molecular dynamics ( ... Voir le document complet
15
Influence of myelin proteins on the structure and dynamics of a model membrane with emphasis on the low temperature regime
... on the small momentum transfer diffractometer D16 54 (λ = ...at the ILL, in order to study the mosaic spread and the temperature evolution of the repeat dis- tances ... Voir le document complet
11
Correlation between local structural dynamics of proteins inferred from NMR ensembles and evolutionary dynamics of homologues of known structure.
... The correspondence between the native state conformational ensembles and the conformational heterogeneity observed in crystal structures have been studied extensively (Best, Lindorff-Larsen, ... Voir le document complet
22
Methyl-Specific Isotope Labeling Strategies for NMR Studies of Membrane Proteins
... probes of structure, dynamics and interactions in protein NMR ...as membrane proteins in a membrane- mimicking ...discuss the approach for labelling ... Voir le document complet
17
NMR methods for intrinsically disordered proteins : application to studies of NS5A protein of hepatitis C virus
... identified by bioinformatic analysis. This model was confirmed by limited proteolysis and mass spectrometry ...cleavage of NS5A yielded two major cleavage sites in the low complexity ... Voir le document complet
259
NMR secondary structure and interactions of recombinant human MOZART1 protein, a component of the gamma-tubulin complex
... composed of at least six different proteins, with molecular masses ranging from 70 to 210 kDa and present in single or multiple copies in the ...1 The overall architecture of ... Voir le document complet
15
Development and application of fast NMR methods for the study of protein structure and dynamics
... dimensional protein NMR ...proven a useful tool for the structural and dynamical characterization of biological ...tidimensional NMR is also very powerful for real-time ... Voir le document complet
240
Structure and dynamics of the outer membrane protein A from Klebsiella pneumoniae: a joint NMR–SMFS–proteolysis and MS approach
... steps of the purification procedure, during which the protein-detergent micelles form in the presence of a large excess of zwittergent ...maintain the β ... Voir le document complet
205
The mechanics of membrane proteins is a signature of biological function
... reveal the mechanical heterogeneity of the plasma membrane, allowing examination of the mechanical nanoenvironment of individual proteins and the flexibility ... Voir le document complet
9
Genomics and structure/function studies of Rhabdoviridae proteins involved in replication and transcription.
... varied by five to ten residues. Disappointingly none of these constructs showed any improvement in the level of soluble expression suggesting that either ...not the appropriate ... Voir le document complet
44
Experimental and numerical studies of the flow structure generated by a submerged sluice gate
... opening and large submergence may lead to much higher values of C c than the typical value of ...modify the velocity distribution, and introduce energy dissipation and ... Voir le document complet
7
The dynamics of lysozyme from bacteriophage lambda in solution probed by NMR and MD simulations.
... play a significant degree of mobility in ...supported by the MD simulations, which show fluctuat- ing b-sheet hydrogen bonds in the lower lip region and dy- namic helical turns ... Voir le document complet
9
A Unified Description of Intrinsically Disordered Protein Dynamics under Physiological Conditions Using NMR Spectroscopy
... in a small petri dish containing a grid for ...with the animal pole upward for injection of labelled proteins in this ...using a Nanoject II (Drummond) and 250 oocytes were each ... Voir le document complet
31
Structure of the benzene dimer - governed by dynamics
... in the 1D models for hindered stem rotation only. [1, 9] The splittings D,2D,D between consecutive levels in these quartets show the measured 1:2:1 ratio, typical for sixfold hindered rotation ... Voir le document complet
5
Studying dynamics without explicit dynamics: A structure‐based study of the export mechanism by AcrB
... description of these two aspects is of course very hard, as dynamics span multiple time scales over which stabilization occurs ...on a number of domains (PN1, PN2, PC1, PC2, DN ... Voir le document complet
53
Studying dynamics without explicit dynamics: a structure-based study of the export mechanism by AcrB
... efflux: the example of AcrB Resistance-nodulation-cell division (RND) ...transporters. The periplasm of gram negative bac- teria may be seen as a buffer zone helping manage cytotoxic ... Voir le document complet
52
Structure and dynamics of ND₃BF₃ in the solid and gas phases : a combined NMR, neutron diffraction, and Ab initio study
... mol. 5 Fluorine-19 and proton T 1 measurements yield barriers (21) Frisch, M. J.; Trucks, G. W.; Schlegel, H. B.; Scuseria, G. E.; Robb, M. A.; Cheeseman, J. R.; Zakrzewski, V. G.; Montgomery, J. A., ... Voir le document complet
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