[PDF] Top 20 Forcing alpha-cell-mediated beta-cell regeneration
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Forcing alpha-cell-mediated beta-cell regeneration
... β-like cell mass as outlined by circulating insulin ...clear regeneration of their β-cell mass monitored 5, 10, 30, and 80 days poststreptozotocin administration ... Voir le document complet
161
Vascular density and endothelial cell expression of integrin alpha v beta 3 and E-selectin in murine tumours.
... form cell-cell contacts to construct patent blood vessels (reviewed in 2 ...] mediated by endothelial cell adhesion molecules (CAMs) represented by four principal classes: the selectins, which ... Voir le document complet
10
DeltaNp63 isoform-mediated beta-defensin family up-regulation is associated with (lymph)angiogenesis and poor prognosis in patients with squamous cell carcinoma.
... &KLFNHQ FKRULRDOODQWRLF PHPEUDQH &$0 DQJLRJHQHVLVDVVD\ 2Q HPEU\RQLF GD\ D ZLQGRZ ZDV RSHQ LQWR WKH VKHOO RI IHUWLOL]HG FKLFNHQ HJJV )RXU GD\V ODWHU PHWK\OFHOOXORVH PP VSRQJHV ... Voir le document complet
13
Myc is required for beta-catenin-mediated mammary stem cell amplification and tumorigenesis.
... The mammary epithelium consists of two layers: lu- minal secretory cells and basal myoepithelial cells. Dur- ing lactation, luminal cells produce and secrete milk in response to hormone stimulation. In addition to the ... Voir le document complet
12
Regeneration of airway epithelial cells to study rare cell states in cystic fibrosis
... Summary and future directions: Single-cell experiments have highlighted novel cell states, pulmonary ionocytes and precursors of MCCs in human AECs. Many questions remain to be addressed: 1) what is the ... Voir le document complet
12
Mechanisms of coronavirus cell entry mediated by the viral spike protein
... the cell surface, activation of viral fusion results in cell-cell fusion and formation of giant multinucleated cells named ...involves cell membranes fusing together, reflects the fusion ... Voir le document complet
24
Cell therapy induced regeneration of severely atrophied mandibular bone in a clinical trial
... Recent preclinical studies have shown that BCP cer- amics consisting of 20% hydroxyapatite (HA) and 80% beta tricalcium phosphate (β-TCP) are appropriate matrices for MSC culture in vitro and bone formation in ... Voir le document complet
16
Calcitonin gene-related peptide inhibits Langerhans cell-mediated HIV-1 transmission.
... Brief Definitive Report HIV-1 gains access into the body mainly during sexual intercourse, by crossing epithelial barriers that cover mucosal surfaces of both the male and female genital tracts. In stratified epithelia, ... Voir le document complet
11
Single-cell analysis of thymocyte differentiation: identification of transcription factor interactions and a major stochastic component in $\alpha\beta$-lineage commitment.
... ). While selecting primers with similar efficiency is usually an easy task, simultaneously preventing competition usually requires the selection of primers from very different parts of the gene. These different locations ... Voir le document complet
13
T helper cell mediated-tolerance towards fetal allograft in successful pregnancy
... Functional activities of Th1, Th2, Th17 CD4+ cells CD4+ Th1 cells produce interleukin (IL)-2, tumor necrosis factor (TNF)-β and interferon (IFN)-γ and are the main effectors of phagocyte-mediated host defense, ... Voir le document complet
6
Pregnane X-receptor promotes stem cell-mediated colon cancer relapse
... Received: March 23, 2016 Accepted: May 29, 2016 Published: July 18, 2016 ABSTRACT Colorectal cancer lethality usually results from post-treatment relapse in the majority of stage II-IV patients, due to the enhanced ... Voir le document complet
17
Enhanced cell-cell contact stability and decreased N-cadherin-mediated migration upon fibroblast growth factor receptor-N-cadherin cross talk
... N-cadherin cell surface accumulation by reducing its ...of cell surface expression of ...separate cell membrane and internal cell areas on each ...following cell surface ... Voir le document complet
59
Differentially activated macrophages orchestrate myogenic precursor cell fate during human skeletal muscle regeneration.
... satellite cell activity during skeletal muscle tissue ...satellite cell pool ...requires cell-cycle withdrawal and expression of the myogenic programme including the expression of the myogenic ... Voir le document complet
44
Regulation of the memory T cell development and islet beta-cell survival by DAPK-related apoptosis-inducing protein kinase 2 (Drak2)
... ABSTRACT Drak2 is a death-associated protein (DAP) family serine threonine kinase. Its expression and roles in the immune system were investigated in this study. According to in situ hybridization, Drak2 expression was ... Voir le document complet
202
Cell-State Transitions Regulated by SLUG Are Critical for Tissue Regeneration and Tumor Initiation
... stem cell activity and differentiation can lead to developmental defects and ...of cell-state transitions in vitro to gain insights into how SLUG/SNAI2, a key developmental transcription factor, modulates ... Voir le document complet
16
RIP3 antagonizes a TSC2-mediated pro-survival pathway in glioblastoma cell death.
... apoptotic cell death in solid ...3)-dependent cell death which is counter-acted by activa- tion of ...in cell death and survival mechanisms occurring in glioblastoma following ...promote cell ... Voir le document complet
12
E4F1 deficiency results in oxidative stress-mediated cell death of leukemic cells.
... or cell death in E4F1 KO HS cells ...of cell death observed in E4F1 KO HS ...and cell death was partly rescued upon treatment with Tiron that allows detoxification of superoxide anions into less ... Voir le document complet
72
Cell sorting by deterministic cell rolling
... – cell rolling and hydrophoresis. For passive cell manipulation we placed slant ridges on the channel floor, which alter the streamlines and induce repeated collisions between cells and the ridges ... Voir le document complet
11
IRF-5-Mediated Inflammation Limits CD8+ T Cell Expansion by Inducing HIF-1alpha and Impairing Dendritic Cell Functions during Leishmania Infection
... gulation of HIF-1 α in DCs does not rely on the effect of a single cytokine. Further investiga- tions are warranted in order to identify the mechanism(s) of HIF-1α induction in DCs during experimental VL. HIF-1α appears ... Voir le document complet
22
Sortilin-derived peptides promote pancreatic beta-cell survival through CREB signaling pathway
... pancreatic beta-cell mass by inflammatory attacks is one of the main pathophysiological features of type 2 diabetes ...preserving beta-cell mass and stimulating in- sulin secretion only in ... Voir le document complet
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