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[PDF] Top 20 T follicular helper and T follicular regulatory cells have different TCR specificity

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T follicular helper and T follicular regulatory cells have different TCR specificity

T follicular helper and T follicular regulatory cells have different TCR specificity

... a different repertoire between Tfr and Tfh ...of follicular CD4 þ CXCR5 þ PD-1 þ T cells on popliteal LNs of 1D2b mice before (left), and 11 days after OVA-IFA immunization (middle), ... Voir le document complet

13

Several Follicular Regulatory T Cell Subsets With Distinct Phenotype and Function Emerge During Germinal Center Reactions

Several Follicular Regulatory T Cell Subsets With Distinct Phenotype and Function Emerge During Germinal Center Reactions

... Tfr cells was the closest to the one of Treg ( 42 ...Tfr cells could be detected using pMHCII tetramers in the draining lymph nodes 11 days post-immunization with OVA/IFA ( 42 ...Tfr cells and ... Voir le document complet

10

Interconnected subsets of memory follicular helper T cells have different effector functions

Interconnected subsets of memory follicular helper T cells have different effector functions

... TEM cells migrate to non-lymphoid sites and are programmed to induce inflammatory responses in situ upon Ag ...we have shown that local memory Tfh cells express mainly the CD62L lo CCR7 − TEM ... Voir le document complet

15

Follicular helper T cells: implications in neoplastic hematopathology.

Follicular helper T cells: implications in neoplastic hematopathology.

... alterations and clonal T- cell receptor (TCR) gene rearrangements in most instances and the identification of clearly malignant morphologic features in some cases (reviewed in de Leval et ...studies ... Voir le document complet

29

Follicular regulatory T cells can be specific for the immunizing antigen and derive from naive T cells

Follicular regulatory T cells can be specific for the immunizing antigen and derive from naive T cells

... B cells that have point mutations introduced into the Ag-binding regions of their B-cell receptor genes by the process of somatic hypermuta- ...B cells are then subjected to selection, and ... Voir le document complet

11

The yin and the yang of follicular lymphoma cell niches: Role of microenvironment heterogeneity and plasticity.

The yin and the yang of follicular lymphoma cell niches: Role of microenvironment heterogeneity and plasticity.

... NK cells, to increase T-cell proliferation and function, and to enhance macrophage-mediated ADCP of Rituximab-coated tumor cells ...T cells [49]. Interestingly, FL infiltrating CD4 pos ... Voir le document complet

33

Helper-like Innate Lymphoid Cells in Humans and Mice

Helper-like Innate Lymphoid Cells in Humans and Mice

... of Helper-like ILCs Helper-like ILCs remained unidentified for many years, and their biological role remained ...Indeed, helper-like ILCs do not appear to be essential for host survival in ... Voir le document complet

18

5-Azacytidine and Rapamycin: different and synergistic effect on ex vivo expansion of natural human T Regulatory cells

5-Azacytidine and Rapamycin: different and synergistic effect on ex vivo expansion of natural human T Regulatory cells

... T regulatory cells (Treg) are challenging to expand ex vivo, and this has severely hindered in vivo evaluation of their therapeutic ...azaC) and Rapamycin (RAPA) are immunosuppressive drugs ... Voir le document complet

1

5-Azacytidine and Rapamycin: different and synergistic effect on ex vivo expansion of natural human T Regulatory cells

5-Azacytidine and Rapamycin: different and synergistic effect on ex vivo expansion of natural human T Regulatory cells

... T regulatory cells (Treg) are challenging to expand ex vivo, and this has severely hindered in vivo evaluation of their therapeutic ...azaC) and Rapamycin (RAPA) are immunosuppressive drugs ... Voir le document complet

1

IL-4/CXCL12 loop is a key regulator of lymphoid stroma function in follicular lymphoma

IL-4/CXCL12 loop is a key regulator of lymphoid stroma function in follicular lymphoma

... dynamic and mutualistic interactions between cancer cells and their surrounding microenvironment drive the coevolution of malignant cells and their supportive niche throughout the life ... Voir le document complet

31

Optimal control of cell mass and maturity in a model of follicular ovulation

Optimal control of cell mass and maturity in a model of follicular ovulation

... The paper is organized as follows. In section 2, we set the optimal control problem, together with our assumptions, and we enunciate the main result. In section 3, we give necessary optimality conditions from HMP ... Voir le document complet

29

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                                                                    fr

en fr Mechanisms implicated in follicular helper T cells polarization and mucosal immunity initiation after intradermal immunization with particles-based antigen Mécanismes impliqués dans la polarisation des lymphocytes T CD4+ folliculaires et l'initiation de l'immunité muqueuse après immunisation intradermique par un antigène particulaire

... Archiving and Animal Models (CNRS laboratory, France) were bred in the specific pathogen free animal facility (Nouvelle Animalerie Commune, Pitié-Salpétrière, ...France) and maintained under ...Germany) ... Voir le document complet

175

Study of the cellular prion protein expression by the follicular dendritic cells in ovine pharyngeal tonsils.

Study of the cellular prion protein expression by the follicular dendritic cells in ovine pharyngeal tonsils.

... If the most likely portal of entry in natural scrapie has been suggested to be the alimentary tract, other potential routes though to be effective experimentally. Sheep and hamsters inoculated with scrapie ... Voir le document complet

1

Different initiation of pre-TCR and γδTCR signalling

Different initiation of pre-TCR and γδTCR signalling

... recruited and activated by phosphorylated CD3e ...particulate and soluble fractions of SCB.29 cells but not ...SCIET.27 cells (Fig. 4A). Phosphorylation was detected in SCIET.27 cells ... Voir le document complet

5

R-spondin2 signaling is required for oocyte-driven intercellular communication and follicular growth

R-spondin2 signaling is required for oocyte-driven intercellular communication and follicular growth

... LGR4/5/6 and RSPO2/3 and can also bind heparan sulfate ...(CyclinD1) and downregulation of Cdkn2a (p21) [ 22 – 24 ...differentiation and is down- regulated in the postnatal ovary [ 26 – 28 ... Voir le document complet

17

Comparative Study of Immune Regulatory Properties of Stem Cells Derived from Different Tissues.

Comparative Study of Immune Regulatory Properties of Stem Cells Derived from Different Tissues.

... adult and nonadult tissue-specific SCs have been characterized, but whether or not these new SC cate- gories exert an immune modulatory function comparable, superior, or inferior to that of MSCs is an ... Voir le document complet

14

Monte Carlo dosimetry of a realistic multicellular model of follicular lymphoma in a context of radioimmunotherapy

Monte Carlo dosimetry of a realistic multicellular model of follicular lymphoma in a context of radioimmunotherapy

... tracted from the MIRD book 42 . Table 2 presents the main properties of the decay of 177 Lu, 131 I and 90 Y. 218 219 Figure 4. β - particle emission spectra of 177 Lu, 131 I and 90 Y from MIRD book 42 . The ... Voir le document complet

35

Regulatory T cells fulfil their promise ?

Regulatory T cells fulfil their promise ?

... cally mismatched stem cells for the treatment of malig- nant diseases. Springer Semin Immunopathol 2004; 26: 155–168. 4 Ciceri F, Labopin M, Aversa F, Rowe JM, Bunjes D, Lewalle P et al. A survey of fully ... Voir le document complet

2

en
                                                                    fr

en fr Phenotypic and functional characterization of different populations of memory folicular helper T cells Caractérisation phénotypique et fonctionnelle des différentes populations de Lymphocytes T CD4 Folliculaires Mémoires

... B cells and long-lived plasma cells ...of Follicular Helper T (Tfh) cells. Effector Tfh cells develop locally in lymphoid organs draining the site of immunization ... Voir le document complet

194

Cell-free DNA in Human Follicular Microenvironment: New Prognostic Biomarker to Predict in vitro Fertilization Outcomes

Cell-free DNA in Human Follicular Microenvironment: New Prognostic Biomarker to Predict in vitro Fertilization Outcomes

... blood and in other biological fluids, are released from apoptotic and/or necrotic ...cancers and gynecological and obstetrics disor- ...in follicular fluid (FF) samples from in vitro ... Voir le document complet

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