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[PDF] Top 20 Expression of programmed death ligand 1 (PD-L1) is associated with poor prognosis in human breast cancer

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Expression of programmed death ligand 1 (PD-L1) is associated with poor prognosis in human breast cancer

Expression of programmed death ligand 1 (PD-L1) is associated with poor prognosis in human breast cancer

... to death due to any cause. Survivors were cen- sored at the date of last ...by expression of PD-L1 were estimated using the Kaplan– Meier product-limit method and compared by ... Voir le document complet

10

The presence of programmed death 1 (PD-1)-positive tumor-infiltrating lymphocytes is associated with poor prognosis in human breast cancer

The presence of programmed death 1 (PD-1)-positive tumor-infiltrating lymphocytes is associated with poor prognosis in human breast cancer

... presence of PD-1 ? TIL and higher stage, grade and worse survival, suggest that PD-1 may also be a can- didate biomarker for predicting response to ...therapy. PD-1 has ... Voir le document complet

10

ICOS is associated with poor prognosis in breast cancer as it promotes the amplification of immunosuppressive CD4+T cells by plasmacytoid dendritic cells

ICOS is associated with poor prognosis in breast cancer as it promotes the amplification of immunosuppressive CD4+T cells by plasmacytoid dendritic cells

... VIew Breast cancer is one of the main causes of death among women in Western countries, and constitutes an important challenge for health care systems ...worldwide. ... Voir le document complet

4

The Splicing FK506-binding protein-51 Isoform Plays a Role in Glioblastoma Resistance Through Programmed Cell Death ligand-1 Expression Regulation

The Splicing FK506-binding protein-51 Isoform Plays a Role in Glioblastoma Resistance Through Programmed Cell Death ligand-1 Expression Regulation

... PD-L1 expression increases with glioma aggressiveness and affects spheroid formation in culture The role of PD-L1 in the apoptosis resistance of GBM ... Voir le document complet

12

Programmed death–ligand 1 and vimentin: A tandem marker as prognostic factor in NSCLC

Programmed death–ligand 1 and vimentin: A tandem marker as prognostic factor in NSCLC

... Considering PDL1 separately, our study shows that its expression was negatively correlated with age, contrary to previous studies [ 16 , 17 ...difference with our observations. A ... Voir le document complet

14

PD-L1 expression with QR1 and E1L3N antibodies according to histological ovarian cancer subtype: A series of 232 cases

PD-L1 expression with QR1 and E1L3N antibodies according to histological ovarian cancer subtype: A series of 232 cases

... types with different characteristics and prognoses: high-grade serous carcinoma (HGSC, 70%), low-grade serous carcinoma (LGSC, <5%), endometrioid carcinoma (EC, 10%), clear-cell car- cinoma (CCC, 10%) and ... Voir le document complet

11

Cytoplasmic PPARγ is a marker of poor prognosis in patients with Cox-1 negative primary breast cancers

Cytoplasmic PPARγ is a marker of poor prognosis in patients with Cox-1 negative primary breast cancers

... PPARγ expression and clinicopathological features or aggressiveness mark- ers, our data demonstrated that nuclear PPARγ expres- sion was inversely correlated with tumor grade, HER2 and N-cadherin ... Voir le document complet

15

PD-L1 expression in TNBC: A predictive biomarker of response to neoadjuvant chemotherapy?

PD-L1 expression in TNBC: A predictive biomarker of response to neoadjuvant chemotherapy?

... women with a histopathologically con- firmed diagnosis of breast cancer treated between January 2006 and December 2014 were consecutively selected for participation in this ...Results: ... Voir le document complet

1

Elevated level of cell-free plasma DNA is associated with breast cancer

Elevated level of cell-free plasma DNA is associated with breast cancer

... collection In total, 115 peripheral blood samples were recruited in this study, which included samples from 32 patients with benign breast lesions and 33 patients with malignant ... Voir le document complet

5

Distinct effects of human glioblastoma immunoregulatory molecules programmed cell death ligand-1 (PDL-1) and indoleamine 2,3-dioxygenase (IDO) on tumour-specific T cell functions.

Distinct effects of human glioblastoma immunoregulatory molecules programmed cell death ligand-1 (PDL-1) and indoleamine 2,3-dioxygenase (IDO) on tumour-specific T cell functions.

... form of TGF-β2, the predominant isoform of TGF-β secreted by GBM cells (Leitlein et ...described in (Thomas and Massagué, 2005) can be obtained by pre-treating T cells typically for 24 hours before ... Voir le document complet

55

Presence of bone metastases(BM) at diagnosis is associated with poor prognosis and coagulation disorders (CD) in patients (pts) with advanced gastric cancer (AGC)

Presence of bone metastases(BM) at diagnosis is associated with poor prognosis and coagulation disorders (CD) in patients (pts) with advanced gastric cancer (AGC)

... series of AGC followed at Cremona Oncology Division from November 2004 to Dicember 2016 and included in three consecutive prospective trials [Dalla Chiesa ...treated with a modified DCF (docetaxel, ... Voir le document complet

1

Hair Repigmentation With Anti-PD-1 and Anti-PD-L1 Immunotherapy: A Novel Hypothesis

Hair Repigmentation With Anti-PD-1 and Anti-PD-L1 Immunotherapy: A Novel Hypothesis

... Repigmentation With Anti–PD-1 and Anti–PD-L1 Immunotherapy: A Novel Hypothesis To the Editor The article by Rivera et al 1 is the first report of a previously ... Voir le document complet

2

The status of PD-L1 and tumor-infiltrating immune cells predict resistance and poor prognosis in BRAFi-treated melanoma patients harboring mutant BRAFV600

The status of PD-L1 and tumor-infiltrating immune cells predict resistance and poor prognosis in BRAFi-treated melanoma patients harboring mutant BRAFV600

... Extension of this observation to clinical prac- tice would require a standardized scoring ...point of view, the PD-1/PD-L1 cross-talk could take place in the context ... Voir le document complet

8

Biomarqueurs des immunothérapies anti-PD-1/PD-L1 : facteurs cliniques, histologiques et immunohistochimiques associés au statut PD-L1

Biomarqueurs des immunothérapies anti-PD-1/PD-L1 : facteurs cliniques, histologiques et immunohistochimiques associés au statut PD-L1

... statut PD-L1 de 92 patients a été déterminé à partir d’un prélèvement ...for Cancer Research) en 2015, concernant la cohorte mélanome de la phase I du pembrolizumab : les métastases hépatiques ... Voir le document complet

75

Cytosine methylation of mature microRNAs inhibits their functions and is associated with poor prognosis in glioblastoma multiforme

Cytosine methylation of mature microRNAs inhibits their functions and is associated with poor prognosis in glioblastoma multiforme

... implicated in transcriptional and post- transcriptional regulation of gene expression [ 1 , 2 ...(RISC) of specific messenger RNAs (mRNAs) through partial base paring of ... Voir le document complet

17

The high protein expression of FOXO3, but not that of FOXO1, is associated with markers of good prognosis

The high protein expression of FOXO3, but not that of FOXO1, is associated with markers of good prognosis

... abundance of total protein expression as previ- ously described 41 ...available in Table ...variations of expression relative to the median expression of the series ... Voir le document complet

11

Influence Du Cisplatine sur l&#039;expression du Check-Point Immunitaire PD-1/PD-L1 Dans Le Cancer Broncho-Pulmonaire Non A Petites Cellules

Influence Du Cisplatine sur l'expression du Check-Point Immunitaire PD-1/PD-L1 Dans Le Cancer Broncho-Pulmonaire Non A Petites Cellules

... de PD-L1 dans divers cancers, et concluaient que ce type de chimiothérapie systémique pourrait améliorer l’efficacité anti-tumorale d’un traitement consécutif par ICI (Tran et ...expériences in vivo ... Voir le document complet

212

TERT promoter status and gene copy number gains: effect on TERT expression and association with prognosis in breast cancer

TERT promoter status and gene copy number gains: effect on TERT expression and association with prognosis in breast cancer

... correlate with MYC overexpression [35, 36]. In line with these findings, we observed that MYC and TERT expression levels are significantly ...MYC is a primary transcription factor ... Voir le document complet

13

Immunothérapie dans le cancer bronchique non à petites cellules : étude rétrospective de l’utilisation des anti PD-1/PD-L1 au sein d’un Centre Régional de Lutte Contre le Cancer

Immunothérapie dans le cancer bronchique non à petites cellules : étude rétrospective de l’utilisation des anti PD-1/PD-L1 au sein d’un Centre Régional de Lutte Contre le Cancer

... population PD-L1 positive et la population PD-L1 négative ni en termes de SSP ni en termes de ...de PD-L1 a montré que ce marqueur n’avait pas de valeur prédictive du bénéfice en ... Voir le document complet

88

Increased expression of the HDAC 9 gene is associated with antiestrogen‐resistance of breast cancers

Increased expression of the HDAC 9 gene is associated with antiestrogen‐resistance of breast cancers

... L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d’enseignemen[r] ... Voir le document complet

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