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[PDF] Top 20 PTP1B expression is an independent positive prognostic factor in human breast cancer

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PTP1B expression is an independent positive prognostic factor in human breast cancer

PTP1B expression is an independent positive prognostic factor in human breast cancer

... of PTP1B as a negative regulator of the insulin and leptin signaling pathways has been exten- sively studied, its role in cancer metabolism remains ...that PTP1B can exert both ... Voir le document complet

8

Expression of the putative tumor suppressor gene PTPN13/PTPL1 is an independent prognostic marker for overall survival in breast cancer.

Expression of the putative tumor suppressor gene PTPN13/PTPL1 is an independent prognostic marker for overall survival in breast cancer.

... L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d’enseignemen[r] ... Voir le document complet

25

Prognostic significance of urokinase plasminogen activator and plasminogen activator inhibitor-1 mRNA expression in lymph node- and hormone receptor-positive breast cancer.

Prognostic significance of urokinase plasminogen activator and plasminogen activator inhibitor-1 mRNA expression in lymph node- and hormone receptor-positive breast cancer.

... RT-PCR in the primary tumors, has the strongest prognostic value for MFS and ...the prognostic value of PAI-1 is stronger that of ...and breast cancer specific survival in ... Voir le document complet

10

Expression of programmed death ligand 1 (PD-L1) is associated with poor prognosis in human breast cancer

Expression of programmed death ligand 1 (PD-L1) is associated with poor prognosis in human breast cancer

... by expression of PD-L1 were estimated using the Kaplan– Meier product-limit method and compared by log-rank ...the expression of PD-L1 by tumor cells was an independent predictor of survival, ... Voir le document complet

10

Systematic functional perturbations uncover a prognostic genetic network driving human breast cancer

Systematic functional perturbations uncover a prognostic genetic network driving human breast cancer

... Whereas prognostic classifiers have proven useful in identifying good-prognosis patients who should be spared from adjuvant chemotherapy [1, 2, 4, 24-26], they have not yet been explored in guiding ... Voir le document complet

16

Disease management patterns for postmenopausal women in Europe with hormone-receptor-positive, human epidermal growth factor receptor-2 negative advanced breast cancer.

Disease management patterns for postmenopausal women in Europe with hormone-receptor-positive, human epidermal growth factor receptor-2 negative advanced breast cancer.

... but an indeterminate number of, HT lines, and without defining HT response 3 ...Chemotherapy is the recommended treatment when there is clear evidence of resistance to ...guidance is provided ... Voir le document complet

10

Prognostic value of PDL1 expression in pancreatic cancer

Prognostic value of PDL1 expression in pancreatic cancer

... factor for Tregs, and its effective cytokine IL10, were associated with PDL1 upregulation in pancreatic ...cells. In agreement with our data, Geng et al reported an increased prevalence of ... Voir le document complet

14

Microtubule-associated tumor suppressors as prognostic biomarkers in breast cancer

Microtubule-associated tumor suppressors as prognostic biomarkers in breast cancer

... lattice in interphase and decorates the mitotic spindle and spindle poles during mitosis ...the human centrosome-cilium interactome also revealed that ATIP3/MTUS1 belongs to a centrosomal protein network ... Voir le document complet

16

Tumor collagenase stimulatory factor (TCSF) expression and localization in human lung and breast cancers.

Tumor collagenase stimulatory factor (TCSF) expression and localization in human lung and breast cancers.

... TCSF is not known, some recent in vitro studies have shown that TCSF is able to stimulate the production of several MMPs by ...3 in fibroblasts (Kataoka et al. 1993). However, stromelysin 3 ... Voir le document complet

7

CD200 is a new prognostic factor in multiple myeloma.

CD200 is a new prognostic factor in multiple myeloma.

... MMC in an initial series of 48 patients with newly-diagnosed MM with the GEP of normal BM plasma cells, normal plasmablasts and normal memory B cells using Affymetrix U133 A+B DNA-microarrays, we found a ... Voir le document complet

13

Dual SIRT1 expression patterns strongly suggests its bivalent role in human breast cancer

Dual SIRT1 expression patterns strongly suggests its bivalent role in human breast cancer

... ABSTRACT Breast cancer is the most common cancer in women, and the leading cause of cancer death in women ...1 is a class-III histone deacetylase involved in ... Voir le document complet

9

Resistance to therapy in estrogen receptor positive and human epidermal growth factor 2 positive breast cancers: progress with latest therapeutic strategies.

Resistance to therapy in estrogen receptor positive and human epidermal growth factor 2 positive breast cancers: progress with latest therapeutic strategies.

... Indeed, in a recent meta-analysis including more than 6000 patients, von Minckwitz and colleagues showed that pCR is not prognostic in HER2- positive ER-positive BC [von ... Voir le document complet

21

The presence of programmed death 1 (PD-1)-positive tumor-infiltrating lymphocytes is associated with poor prognosis in human breast cancer

The presence of programmed death 1 (PD-1)-positive tumor-infiltrating lymphocytes is associated with poor prognosis in human breast cancer

... It is important to note that the presence of PD-1 ? TIL is differentially associated with the intrinsic subtypes of breast ...TIL is the highest in the basal-like subtype and the lowest ... Voir le document complet

10

Human epidermal growth factor receptor 2 expression in early breast cancer patients: a Swiss cost-effectiveness analysis of different predictive assay strategies

Human epidermal growth factor receptor 2 expression in early breast cancer patients: a Swiss cost-effectiveness analysis of different predictive assay strategies

... Discussion We modelled the cost–effectiveness of different predic- tive HER-2 testing strategies, prior to trastuzumab treatment of adjuvant breast cancer patients, from a Swiss health system perspective. ... Voir le document complet

11

Prognostic impact of epidermal growth factor receptor (EGFR) expression on loco-regional recurrence after preoperative radiotherapy in rectal cancer.

Prognostic impact of epidermal growth factor receptor (EGFR) expression on loco-regional recurrence after preoperative radiotherapy in rectal cancer.

... reported in many malignant human cell lines [17-19]. This activation is similar to the one produced by physiological concentra- tions of EGF ...[22-24]. An inverse relation between the number ... Voir le document complet

11

The human epidermal growth factor receptor 2 (HER2) in the breast cancer : from measurement to targeted treatment

The human epidermal growth factor receptor 2 (HER2) in the breast cancer : from measurement to targeted treatment

... Introduction Human epidermal growth factor receptor 2 (HER2) is a transmembrane tyrosine kinase receptor belonging to the family of epidermal growth factor receptors (EGFR) ...protein ... Voir le document complet

334

Lack of prognostic impact of sentinel node micro-metastases in endocrine receptor-positive early breast cancer: results from a large multicenter cohort☆

Lack of prognostic impact of sentinel node micro-metastases in endocrine receptor-positive early breast cancer: results from a large multicenter cohort☆

... study is also the first one generating a 1 : 1 : 1 matched pN0(i ), pN1mi, and pN1macro ...features in the other two groups. Thus, patients in the 1 : 1 : 1 matching cohort no longer differed for ... Voir le document complet

10

Elucidating the altered transcriptional programs in breast cancer using independent component analysis

Elucidating the altered transcriptional programs in breast cancer using independent component analysis

... programs in breast cancer using Independent Component ...technology is enabling genetic diseases like cancer to be studied in unprecedented detail, at both transcriptomic ... Voir le document complet

16

TTK/hMPS1 is an attractive therapeutic target for triple-negative breast cancer

TTK/hMPS1 is an attractive therapeutic target for triple-negative breast cancer

... the expression of TTK at the mRNA level in the different tumor subtypes (41 TNBC; 30 Her2; 30 LB and 29 LA) and in 11 healthy tissue ...and in normal breast tissues ...obtained ... Voir le document complet

16

aHIF but not HIF-1alpha transcript is a poor prognostic marker in human breast cancer.

aHIF but not HIF-1alpha transcript is a poor prognostic marker in human breast cancer.

... 80% in patients with low aHIF expression and 45% in patients with high aHIF ...that in patients with a low concentration of HIF-1α ...0.017) in univariate analyses. In ... Voir le document complet

9

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