[PDF] Top 20 Expression of Galectin-7 Is Induced in Breast Cancer Cells by Mutant p53
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Expression of Galectin-7 Is Induced in Breast Cancer Cells by Mutant p53
... marker of epithelial differentiation expressed in the stratified epithelium of various ...members of the galectin family, its expression level is often significantly ... Voir le document complet
10
O-GlcNAcylation-Inducing Treatments Inhibit Estrogen Receptor α Expression and Confer Resistance to 4-OH-Tamoxifen in Human Breast Cancer-Derived MCF-7 Cells.
... MCF-7 cells from 4OH-tamoxifen-induced cell death. (A) MCF-7 cells were co- transfected with cDNAs coding for the PH domain of Akt fused to luciferase (Luc-Akt-PH) and YFP fused ... Voir le document complet
18
The CCAAT/Enhancer-Binding Protein Beta-2 Isoform (CEBPbeta-2) Upregulates Galectin-7 Expression in Human Breast Cancer Cells
... Our in silico analysis of the human galectin-7 promoter has revealed some other interesting features, most notably within the C/EBP binding site located at position 2147/2132 ...genome-wide ... Voir le document complet
8
Induction by estrogens of methotrexate resistance in MCF-7 breast cancer cells
... Development of drug resistance is a major factor that limits the effectiveness of chemotherapy ...treatments. In this study, we determined whether estradiol or its metabolites 2-, 4- and 16 ... Voir le document complet
8
Bifunctional ligand design for modulating mutant p53 aggregation in cancer
... complexity of p53 stabilization and activation, Cell Death ...Regulation of p53 activity through lysine methylation, Nature, 2004, 432(7015), 353–360; (e) ...Design of Small-Molecule ... Voir le document complet
14
Expression and functions of galectin-7 in human and murine melanomas
... identification of galectin-7 as a p53-induced gene and its ability to induce apoptosis in many cell types support the hypothesis that galectin-7 has strong ... Voir le document complet
10
The role of histone variant H2A.Z in the regulation of gene expression in breast cancer cells
... regulation of the p21 gene is mediated by dynamic binding of the histone variant ...to p53 binding sites within the p21 promoter region in p53 positive cells, such ... Voir le document complet
125
Deregulated expression of pro-survival and pro-apoptotic p53-dependent genes upon Elongator deficiency in colon cancer cells.
... pathway in HCT116 cells SGK is a pro-survival factor [35] but it was unclear whether its enhanced expression modulates the apoptotic response of IKAP/hELP1 depleted cells to ... Voir le document complet
13
Biochemical disorders induced by cytotoxic marine natural products in breast cancer cells as revealed by proton NMR spectroscopy-based metabolomics
... sources of a huge number of pharmacologically active compounds, some of which exhibit antineoplastic activity of clinical ...mechanism of action of marine natural products (MNPs) ... Voir le document complet
37
Breast cancer stem cell-like cells generated during TGFβ-induced EMT are radioresistant
... tumor cells first respond to conventional treatments and then recur ...Failure of conventional treatments has commonly been associated with CSCs survival ...characteristic of CSCs from various tumor ... Voir le document complet
14
Cytosolic galectin-7 impairs p53 functions and induces chemoresistance in breast cancer cells
... Generation of stable transfectants expressing gal-7 and gal-7 R74S To obtain stable MCF-7 breast carcinoma transfectants expressing gal-7, the cDNA encoding the human ... Voir le document complet
10
Expression and functions of galectin-7 in ovarian cancer
... It is becoming clear that gal-7 plays a central role in cancer of epithelial ...progression of many types of carcinoma. This has been well established in ... Voir le document complet
17
Galectin-7 Expression Potentiates HER-2-Positive Phenotype in Breast Cancer
... subtypes of breast cancer and are frequently associated with metastasis and poor ...subtypes of breast cancer, these tumors are associated with abnormally high expression ... Voir le document complet
12
Homologous recombination induced by replication inhibition, is stimulated by expression of mutant p53
... null p53 mutant and possibly with a dierent tumor spectrum (Jimenez et ...transformed in vitro by cooperating oncogenes suggest- ing that additional genetic changes were required for ... Voir le document complet
6
Prognostic value of the expression of C-Chemokine Receptor 6 and 7 and their ligands in non-metastatic breast cancer.
... a-SMA expression or with dendritic morphology, but not on tumor ...cells. In previously reported series, CCR7 expression had been described on tumor cells from breast ... Voir le document complet
11
Acquisition of a hybrid E/M state is essential for tumorigenicity of basal breast cancer cells
... Institute of Technology, Cambridge, MA 02139 Contributed by ...reviewed by Filippo G. Giancotti and Arthur M. Mercurio) Carcinoma cells residing in an intermediate phenotypic state ... Voir le document complet
13
IL-8 expression and its possible relationship with estrogen-receptor-negative status of breast cancer cells.
... HAL is a multi-disciplinary open access archive for the deposit and dissemination of sci- entific research documents, whether they are pub- lished or ...institutions in France or abroad, or from ... Voir le document complet
8
Survivin contributes to DNA repair by homologous recombination in breast cancer cells
... Breast cancer Homologous recombination Introduction In the last decade, Survivin has attracted considerable attention as a therapeutic target for anticancer strategies because of its dual ... Voir le document complet
11
Stem Cells Inhibition by Bevacizumab in Combination with Neoadjuvant Chemotherapy for Breast Cancer
... 10 of 15 could stimulate the population of CSCs and contribute to the resistance of these drugs and the lack of survival benefit provided by these compounds in breast ... Voir le document complet
16
The presence of LC3B puncta and HMGB1 expression in malignant cells correlate with the immune infiltrate in breast cancer
... T cells (Treg, ...density of the in filtrate by these distinct subsets was correlated among each other in a positive fashion ( ...macrophage-rich breast can- cers tend to contain ... Voir le document complet
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