[PDF] Top 20 Expansion of regulatory T cells in patients with Langerhans cell histiocytosis.
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Expansion of regulatory T cells in patients with Langerhans cell histiocytosis.
... with LCH was suggested by their phenotype (CD4 þ CD25 high FoxP3 high ), their intimate contact with LCH histiocytes (Figure 3A), their ability to inhibit T cell proliferation in vitro (see ... Voir le document complet
12
High viral load of Merkel cell polyomavirus DNA sequences in Langerhans cell sarcoma tissues.
... Dendritic cells and the control of ...disorders of children and adults: introduction to the problem, overview, historical perspective and ...epidemiology. In Histiocytic disorders of ... Voir le document complet
5
CD4CD8aa Lymphocytes, A Novel Human Regulatory T Cell Subset Induced by Colonic Bacteria and Deficient in Patients with Inflammatory Bowel Disease
... ratio, with bacteria or monocytes (when autologous monocytes were not available a mixture of monocytes from four donors were used to permit the sharing of HLA class-II alleles between the monocytes ... Voir le document complet
17
Regulatory activity of azabisphosphonate-capped dendrimers on human CD4+ T cell proliferation enhances ex-vivo expansion of NK cells from PBMCs for immunotherapy
... incubation with increasing concentration of 3a-G1-Julo, we observed an increase in the mean fluorescence inten- sity of the cells, indicating a progressive labelling of the ... Voir le document complet
14
Regulatory role of natural killer T cells in diabetes
... T cells had a Th1 bias, as they lost the ability to secrete IL-4, and mainly produced IFN-g after anti-CD3 stim- ulation [65] ...quency of iNKT cells not only among newly diagnosed and long-diagnosed ... Voir le document complet
13
Plasmacytoid dendritic cells deficient in IFNα production promote the amplification of FOXP3+regulatory T cells and are associated with poor prognosis in breast cancer patients
... cancers of different histological origin. Of note, we also observed that (1) TApDCs were in close contact with tumor-associated Tregs (TATregs) within lymphoid aggregates in BTs and (2) ... Voir le document complet
4
Type 1 regulatory T cells specific for collagen type II as an efficient cell-based therapy in arthritis
... effect of Col-Tregs in the CAIA model. The results of the present pharmacokinetic studies of injection of Col-Treg cells in arthritis confirm previous observations ... Voir le document complet
12
Acute-phase ITIH4 levels distinguish multi-system from single-system Langerhans cell histiocytosis via plasma peptidomics
... Background: Langerhans cell histiocytosis (LCH) is a proliferative disorder in which abnormal Langerhans cell (LC)-like cells (LCH cells) intermingle with ... Voir le document complet
10
Functional regulatory T cells are collected in stem cell autografts by mobilization with high-dose cyclophosphamide and granulocyte colony-stimulating factor.
... doses of Cy have a specific toxicity to Treg in rodents, leading to Treg apoptosis and loss of function (17-19, 34, ...39). In particular, Ghiringhelli et ...injection of a low dose ... Voir le document complet
34
Low-dose interleukin-2 fosters a dose-dependent regulatory T cell tuned milieu in T1D patients
... T cells (Teffs) survive thymic deletion and populate the periphery. In the normal immune system, these autoreactive Teffs do not mediate autoimmunity as their expansion and function are inhibited by ... Voir le document complet
40
Role and prognostic importance of regulatory T cells in lung cancer patients, according to the presence of tertiary lymphoid structures
... 2.5.2. Expansion and activation of Tregs In tumor microenvironment, several cues are responsible for the differentiation and activation of Tregs apart from the TCR/CD28 ...the expansion ... Voir le document complet
277
Role of Regulatory T Cell and Effector T Cell Exhaustion in Liver-Mediated Transgene Tolerance in Muscle
... probability of presentation by H-2Kb MHC class I molecules were identified by the Immune Epitope Database ( ...GeneCust. Cells were stimulated either with one of these peptides or with 1 ... Voir le document complet
19
Alloantigenic recognition properties of CD8+ regulatory T cells
... regions of donor MHC molecules [2,3]. Sixty-two over- lapping peptides of sixteen amino acids (aa) were tested in a coculture of Tregs with syngeneic pDCs (ratio ...repertoire of ... Voir le document complet
2
Innate-like T cells in children with sickle cell disease
... controls. In these different T cell populations, IL-17 production did apparently not increase further during VOC, which is concordant with the data reported for IL-17 plasma levels [ 9 , 10 ...T ... Voir le document complet
16
Lymph Node Stromal Cells Generate Antigen-Specific Regulatory T Cells and Control Autoreactive T and B Cell Responses
... stromal cells subsets and CD45 + fraction was used to sort B cells (CD45 + CD19 + ), M Fs (CD45 + CDllb + CDllc - ) and DCs (CD45 + CDllb int CDllc + ...characterization of cell lines, stromal ... Voir le document complet
20
Regulatory T cell plasticity: another layer of complexity in atherosclerosis
... Thcells in the periphery under the influence of different stimulations, especially TGF- 6 ...subsets of Tregs that do not express FoxP3 have been described. Tr-1 cells are characterized by ... Voir le document complet
8
Ca 2+ -activated cleavage of ezrin visualised dynamically in living myeloid cells during cell surface area expansion
... DISCUSSION In this paper, we have presented evidence that ezrin cleavage occurs during non-restricted Ca 2+ influx and locally in the phagocytic ...separation of two fluorescent tags on ezrin ... Voir le document complet
10
Monitoring NK cell activity in patients with hematological malignancies
... activity of NK cells against autologous tar- get cells coated with anti-CD20 antibodies prior to use would hence be helpful to identify those patients that have the high- est chances to ... Voir le document complet
7
OA031-02. Regulatory T cells inhibit CD8 T cell proliferation in HIV-1 infection through CD39/adenosine pathway
... Center of Infectious and Parasitic Diseases, Sofia, Bulgaria, 2 INSERM, Unité U955, Créteil, France and 3 Immunologie clinique, AP-HP, Groupe Henri-Mondor Albert-Chenevier; Université Paris 12, Créteil, ... Voir le document complet
2
Regulatory T cells fulfil their promise ?
... side of infectious risk, by positively selecting CD34 + hematopoietic stem progeni- tor cells in the near-absence of T ...chance of infectious death, such as through infusing cytotoxic ... Voir le document complet
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