Haut PDF Epigenetic regulation of innate immune responses to infection
Epigenetic regulation of innate immune responses to infection
... importance of epigenetic modifications in the control of gene expression is widely ...altered epigenetic patterns themselves invoke transcriptional modulation or are instead downstream ...
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Innate immune response of primary human keratinocytes to West Nile virus infection and its modulation by mosquito maliva
... expression of ISGs. Induction of several ISG mRNA expression such as IFIT-1 to 3, viperin, OAS1, MX1 and ISG20, was observed in WNV-infected ...cell infection with WNV ( Jiang et ...WNV ...
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Solute Carrier NTCP Regulates Innate Antiviral Immune Responses Targeting Hepatitis C Virus Infection of Hepatocytes.
... causes of liver dis- ease and cancer ...HCV infection. Using gain- and loss-of-function studies, we show that NTCP mediates HCV infection of hepatocytes and is relevant for ...
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The Timing of IFN beta Production Affects Early Innate Responses to Listeria monocytogenes and Determines the Overall Outcome of Lethal Infection
... opposed to recognition by a cell surface receptor could lead to specific pathogen ...sought to determine whether the delay in IFNb production could provide a selective advantage for Lm spreading ...
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β2-adrenergic signals downregulate the innate immune response and reduce host resistance to viral infection
... susceptibility to viral infection. Stimulation of the β2-AR pathway was found to be detrimental for host survival to MCMV infection, suggesting that the stress mediators ...
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Host innate immune responses to Acinetobacter baumannii infection
... PATHOGENESIS OF A. BAUMANNII A. baumannii has developed a number of specific and non- specific virulence factors for successful colonization and infection in the ...discussion of the potential ...
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Innate and acquired plasticity of the intestinal immune system.
... g of lumenal material in the colon) [1]. From time to time, food and water supplies introduce exogenous pathogenic microbes that are specifically equipped to invade the mucosa ...“ignorance” ...
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Evolutionary plasticity in the innate immune function of Akirin
... action of transcription factors, chroma- tin remodelling complexes and RNA ...in immune gene expression in insects and mammals, linking the SWI/ SNF chromatin-remodelling complex with the transcription ...
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Deciphering the genetic control of innate and adaptive immune responses in pig: a combined genetic and genomic study
... µg of total RNA from both blood samples and the reference sample (RNAs derived from a pool of tissues) were reverse-tran- scribed and directly labeled by Cy3 and Cy5, respec- tively, using the ChipShot TM ...
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View of Involvement of innate immunity beyond response to infection — Atherosclerosis: an inflammatory disease
... Journal of Medicine que l ’injection d’anticorps anti-CD3, qui induit une augmentation des Tregs et leur activité dépendante du TGF β, prévenait l’apparition du diabète chez des jeunes adultes prédiabétiques ...
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Immune evasion, immunopathology and the regulation of the immune system.
... Role of Antigenic Exposure In addition to experimental work on animal models, the potential role played by the coevolutionary interactions between hosts and parasites in shaping patterns of ...
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Innate Immune Response to Streptococcus pyogenes Depends on the Combined Activation of TLR13 and TLR2
... pyogenes infection triggers TLR2 and Unc93b1-dependent TLR13 responses TLR13 has been localized to endosomes suggesting that the recognition of ...exposure of cells to S. ...
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Innate immune cells and their contribution to T-cell-based immunotherapy
... function of tumor-infiltrating neutrophils has shown to improve the effectiveness of T-cell-based immunotherapies, such as ICB and ...model of melanoma, the inhibition of the receptor ...
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View of Involvement of innate immunity beyond response to infection — Innate immunity and acute renal failure
... Les récepteurs NLR sont uniquement intracellulaires. Plus de 23 membres de cette famille ont jusqu ’à maintenant été décrits (NOD1 à 4, CITA, IPAF, NAIP, NLRP, NAIP …). Bien que les ligands et les fonctions de ces ...
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Epigenetic regulation of transcription in intermediate heterochromatin
... sequence of MULE-F19G14 with other MULEs. The structure and positions of annotated genes are indicated as in Fig ...similarities to other MULEs (expected value cutoff ¼ 3 in BLASTN) are shown as bars ...
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Phenotyping of Adaptive Immune Responses in Inflammatory Diseases
... sequencing to determine T cell clonality and/or TCR af finity measurements ( 13 , 14 , 16 ) ( Figures 1A, C ...relevance of activation-based assays has been highlighted by recent data on SARS-CoV-2-speci fic ...
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Distinct systemic and mucosal immune responses to SARS-CoV-2
... understanding of how local and systemic immune responses are dysregulated following SARS-CoV-2 infection and the individual roles that they play in determining severe clinical outcomes in a ...
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CD8 T cell differentiation during immune responses
... Virus Infection 䌤 Ivana Munitic, 1 †* He ´le `ne Decaluwe, 2 † Ce ´sar Evaristo, 1 Sara Lemos, 1 Myriam Wlodarczyk, 3 Andrew Worth, 5 Agne `s Le Bon, 1 § Liisa ...
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Tissue-specific cellular immune responses to malaria pre-erythrocytic stages
... HAL Id: hal-01700959 https://hal.sorbonne-universite.fr/hal-01700959 Submitted on 5 Feb 2018 HAL is a multi-disciplinary open access archive for the deposit and dissemination of sci- entific research documents, ...
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en fr Regulation of growth: Epigenetic mechanisms? Régulation de la croissance : des mécanismes épigénétiques ?
... Identification of ten loci associated with height highlights new biological pathways in human growth. Nat Genet, 2008. 40(5): p. 584-91. 3. Weedon, M.N., H. Lango, C.M. Lindgren, C. Wallace, D.M. Evans, M. ...
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