[PDF] Top 20 The epigenetic clock as a predictor of disease and mortality risk: a systematic review and meta-analysis

... some of the follow- ing points should be ...with the latter being more susceptible to bias as we identified in this ...Cases and controls must be sampled from the same source population ... Voir le document complet

... meet the eligibility ...duration of follow-up, year of publication), informa- tion about the studied population (number of partici- pants with and without AF, mean age, number ... Voir le document complet

... (AIJ and CL, AIJ and HS) and then reciprocally ...Disagreements of two reviewers were resolved by ...reached, a third reviewer was consulted. The following information from each ... Voir le document complet

... analyses of study characteristics, strati- fied by type of population, method of ascertainment of atrial fibrillation, level of adjustment, year of publica- tion, median ... Voir le document complet

... in the current state of evidence guiding treatment decisions in CLTI, particularly for severe anatomic patterns of disease treated via endovascular ...(30-day) mortality, amputation, ... Voir le document complet

... reducing the mortality associated with smoking. The reality or the extent of such a possible benefit of smoking reduction in avoiding smoking- related mortality ... Voir le document complet

... regardless of pathologic type (cutaneous, mucosal, and ocular), who received immunotherapy with check- point inhibitors at our institute between January 2012 and December 2016, were included in this ... Voir le document complet

... titles and abstracts for relevance and eligibility. The full text of potentially relevant articles was ...available, the corresponding authors were ...articles. The reviewers ... Voir le document complet

... is a multifactorial disease among which oxidative stress may play a major pathophysiological ...conducted a systematic review and meta-analysis to evaluate ... Voir le document complet

... firefighting and police work and that examined associ- ated prostate cancer incidence and/or mortality using any type of relative risk estimator (hazard ratio (HR), odds ratio ... Voir le document complet

... increase the chances of a per- manent colonization and development of periodontitis later on in children? Early studies using culture probably underestimated the prevalence ... Voir le document complet

... L’archive ouverte pluridisciplinaire HAL, est destinée au dépôt et à la diffusion de documents scientifiques de niveau recherche, publiés ou non, émanant des établissements d’enseignemen[r] ... Voir le document complet

... pain and disability in adulthood. Method: A systematic review and meta-analysis of observational studies will be ...following a PECOS approach: population, ... Voir le document complet

... occlusion and an ipsilateral cervical internal carotid artery (c-ICA) high-grade stenosis or occlusion, constitute about 15% of patients undergoing endovascular thrombectomy ...present a unique ... Voir le document complet

... is the first large meta-analysis demonstrating the absence of systematic antibioprophylaxis in prevention of endophthalmitis in intravitreal ...injections. The ... Voir le document complet

... Heme iron intake and risk of colon cancer: a meta-analysis of prospective cohort studies The objective of this part of the review was to assess, through meta-analysis, the magnitude of t[r] ... Voir le document complet

... activity and patient global assessment too ...used a different score with some tests evaluating not only the hand but the arm in its ...used a score (Dreiser functional index (15)) ... Voir le document complet

... In the context of acute coronary syndromes (ACS), TP has been linked to adverse clinical ...present a systematic review and meta-analysis of the ... Voir le document complet

... another epigenetic phenomenon used by miRNAs: miR- 30d is overexpressed in EC where it is able to methylate the H19 locus, which is associated with reproductive and endocrine system disorders as well ... Voir le document complet

... cardiovascular disease. These two characteristics could explain the non- significant tendency of FMD improvement we ...assess the efficacy of two identified strategies because of ... Voir le document complet