[PDF] Top 20 The emerging role of the IL-17B/IL-17RB pathway in cancer
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The emerging role of the IL-17B/IL-17RB pathway in cancer
... Introduction The IL-17 cytokine family and its receptors play crucial roles in normal host immune ...and cancer. The IL-17 family includes six members (IL-17A to IL-17F) with different ... Voir le document complet
20
Potential role of the 3-mercaptopyruvate sulfurtransferase (3-MST)—hydrogen sulfide (H2S) pathway in cancer cells
... roles in mammalian cells in health and ...emerged in the field of H 2 S biology, showing that various cancer cells upregulate their endogenous H 2 S production, and utilize this ... Voir le document complet
7
The specific in vivo role of PPARgamma and its downstream signaling pathway in the pathophysiology of Osteoarthritis
... elevated in chondrocytes extracted from PPARγ- mTOR double KO mice compared to control mice (Figure 4 ...Our in vitro rescue studies using PPARγ expression vector and in vivo studies using PPARγ- ... Voir le document complet
210
The emerging role of lysine acetylation of non-nuclear proteins
... probably the best characterized HDAC that targets a variety of cytoplasmic ...relevant in cancer as they critically regulate actin remodelling, dynamics of cell adhesion and motility [ ... Voir le document complet
10
The IL-17B-IL-17 receptor B pathway promotes resistance to paclitaxel in breast tumors through activation of the ERK1/2 pathway
... Interleukin 17B (IL-17B) is a pro-inflammatory cytokine that belongs to the IL- 17 cytokines family and binds to IL-17 receptor B ...expression of IL-17B and IL-17RB is ... Voir le document complet
14
Function and regulation of 17B-hydroxysteroid dehydrogenase type7 (17B-HSD7) in sex hormone biosynthesis and breast cancer : in vitro, in vivo, proteomic and three dimensional co-culture studies
... 20 of cells synthesising DNA in S ...(120). The molecular mechanisms of antiestrogens/estrogen suppressive on cell cycle arresting was through the regulation of cyclin-dependent ... Voir le document complet
220
Regulation of positive-strand RNA virus replication: The emerging role of phosphorylation.
... mediate the formation of hepatitis C virus RNA replication complex on lipid ...enhances the ubiquitination and degradation of hepatitis C virus RNAdependent RNA ... Voir le document complet
20
Consequences of blunting the mevalonate pathway in cancer identified by a pluriomics approach
... that the combination of statins and taxanes was a powerful trigger of HGT-1 human gastric cancer cells’ apoptosis 1 ...involved in the “Central carbon metabolism pathway ... Voir le document complet
13
Role of the tumor microenvironment in regulating apoptosis and cancer progression
... growth. The FL microenvironment is rich in Tfh cells (follicular helper T cell) which interact with CD40 receptor expressed on B cells via CD40-L, to produce high quantity of IL-4, an important ... Voir le document complet
25
The re-emerging pathophysiological role of the cystathionine-β-synthase - hydrogen sulfide system in Down syndrome
... shutdown of electron trans- port and suppression of ATP synthesis) than a ‘normal’ ...On the other hand, it is also conceivable (but remains to be experimentally tested) that some of ... Voir le document complet
11
The increasing role of amphiregulin in non-small cell lung cancer.
... resistance in an autocrine manner. The autocrine roles of EGF- like growth factors in lung cancer pathogenesis and in apoptosis resistance have been extensively ...studied. ... Voir le document complet
10
Role of microRNAs in the immune system, inflammation and cancer
... class of gene expression regulators, have emerged as crucial players in various biological processes such as cellular proliferation and differentia- tion, development and ...apoptosis. In addition, ... Voir le document complet
13
Role of XPC in the human cutaneous cancer cells invasion
... and cancer. In human epithelial cancers such as SCC, invasive cells are typically observed to migrate collectively (Friedl and Gilmour ...2009). In collective invasion, carcinoma cells retain their ... Voir le document complet
231
The Emerging Role of Exercise Testing and Stress Echocardiography in Valvular Heart Disease
... Assessment of CAD and hibernating myocardium. The other potential role of dobutamine stress echocardiography in patients with AS and impaired LV function is the detection ... Voir le document complet
10
The relative eosinophil count in breast cancer as an emerging prognostic biomarker
... time in our ongoing data collection, we have looked at a total of 75 patients who had DCIS with microinvasion and 56 patients who had DCIS ...(85.3%) of patients with DCIS with microinvasion had ... Voir le document complet
2
The role of histone variant H2A.Z in the regulation of gene expression in breast cancer cells
... grown in standard medium, treated or not with ...growth in TSA treated cells was partly rescued in cells previously transfected with ...3a). In particular, significant counts of dead ... Voir le document complet
125
The role of COX-2 in rectal cancer treated with preoperative radiotherapy
... whatever the N-stage, or cT1–cT2 with radiological evidence of positive lymph ...treatment. The age of the patients ranged from 28 to 85 (median, 63 years) and the sex ratio was ... Voir le document complet
7
Emerging Roles of ADAM and ADAMTS Metalloproteinases in Cancer
... [78,103]. The ADAMTS-1 story will probably mature in the next few years since some authors have also shown that overexpression of full-length ADAMTS-1 in CHO cells enhances tumour ... Voir le document complet
16
The Complex Subtype-Dependent Role of Connexin 43 (GJA1) in Breast Cancer.
... both in epithelial and stromal cells types. The molecular landscape provided by different cell types and/or by different breast cancer subtypes might provide different context, possibly allowing Cx43 ... Voir le document complet
27
en fr role of the SOCS-1 protein in the colorectal cancer progression Role de la protéine SOCS-1 dans la progression tumorale colique
... with the proximal region of the mouse ...independent of IFN- ␥ and remained after IFN- ␥ ...member of the Sp transcription factor family, has been shown to bind weakly to ... Voir le document complet
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