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[PDF] Top 20 Dynamic epigenetic changes in immune responses to infection in human dendritic cells

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Dynamic epigenetic changes in immune responses to infection in human dendritic cells

Dynamic epigenetic changes in immune responses to infection in human dendritic cells

... important epigenetic mark in ...stable epigenetic modification, it is becoming increasingly viewed as a more dynamic process that involves both active methylation and demethylation ... Voir le document complet

74

Immune-Complexed Adenovirus Induce AIM2-Mediated Pyroptosis in Human Dendritic Cells

Immune-Complexed Adenovirus Induce AIM2-Mediated Pyroptosis in Human Dendritic Cells

... pyroptosis in other FcγR + cells (e.g. neutrophils) occurs in a host with HAdV NAbs during local or systemic injection of HAdV vectors is ...compared to the non-opsonized pathogen [ 100 ]. ... Voir le document complet

30

Bacterial infection remodels the DNA methylation landscape of human dendritic cells

Bacterial infection remodels the DNA methylation landscape of human dendritic cells

... of immune-acti- vated TFs in response to ...regulators to hypomethylated regions is likely associ- ated with the opening of the chromatin in these regions, although it remains unclear ... Voir le document complet

13

Silent infection of human dendritic cells by African and Asian strains of Zika virus

Silent infection of human dendritic cells by African and Asian strains of Zika virus

... IFNs in MoDCs. Virus-infection of MoDCs is leading to the activation of antiviral innate immune mechanisms, with the IFN type I (IFN-α/β) pathway being of central importance to protect ... Voir le document complet

13

Epigenetic regulation of innate immune responses to infection

Epigenetic regulation of innate immune responses to infection

... of epigenetic modifications in the control of gene expression is widely ...altered epigenetic patterns themselves invoke transcriptional modulation or are instead downstream consequences of ... Voir le document complet

169

Acquired immune responses to the seasonal trivalent influenza vaccination in COPD

Acquired immune responses to the seasonal trivalent influenza vaccination in COPD

... mortality in chronic obstructive pulmonary disease (COPD) pa- ...defect in the ability of some COPD patients to mount an adequate humoral response to in- fluenza ...was to ... Voir le document complet

13

αvβ8 integrin-expression by BATF3-dependent dendritic cells facilitates early IgA responses to Rotavirus

αvβ8 integrin-expression by BATF3-dependent dendritic cells facilitates early IgA responses to Rotavirus

... modified to realize the graphical abstract ...Fellowship in Medicine, a Lundbeck Foundation Research Fellowship, the Åke Wiberg Foundation, the Carl Trygger Foundation and the Crafoord ... Voir le document complet

16

Differentiation of human dendritic cell subsets for immune tolerance induction

Differentiation of human dendritic cell subsets for immune tolerance induction

... capacity to secrete IL-10 for each subset obtained has been evaluated by ELISA ( ...due to stimulation. In presence of the pro-inflammatory stimulus, LPS or class A CPG-ODN, IL-12p70 or INF-alpha ... Voir le document complet

7

P11-05. Induction of CD8+ T cell mediated immune responses through skin and mucosa: identification of immunostimulatory versus tolerogenic dendritic cells

P11-05. Induction of CD8+ T cell mediated immune responses through skin and mucosa: identification of immunostimulatory versus tolerogenic dendritic cells

... that in vivo priming of CTL responses was induced by newly recruited DC rather than skin/mucosal resident ...Ag to CD8+ T ...LC in Langerin-DTR mice and the con- tact sensitizer DNFB (which ... Voir le document complet

2

Variability in the virulence of specific Mycobacterium tuberculosis clinical isolates alters the capacity of human dendritic cells to signal for T cells

Variability in the virulence of specific Mycobacterium tuberculosis clinical isolates alters the capacity of human dendritic cells to signal for T cells

... METHODS Human blood peripheral mononuclear cells, MD- DCs and T lymphocytes - Mononuclear cells were iso- lated from buffy coats provided by the State Blood Transfusion Center of Zacatecas, SSA ... Voir le document complet

10

Engineered niches support the development of human dendritic cells in humanized mice

Engineered niches support the development of human dendritic cells in humanized mice

... incubated in 34% sucrose solution (Sigma-Aldrich) overnight at 4 ...embedded in Cryomatrix (Thermo Fisher) and frozen for cryostat sectioning (9 ...For human DCs staining, plug sections were ... Voir le document complet

19

IL-7-Adjuvanted Vaginal Vaccine Elicits Strong Mucosal Immune Responses in Non-Human Primates

IL-7-Adjuvanted Vaginal Vaccine Elicits Strong Mucosal Immune Responses in Non-Human Primates

... Antibody Responses We then tested the capacity of IL-7 to serve as an adjuvant in a mucosal immunization protocol against a model ...DT in 200μL of PBS) sprayed directly into the vaginal ... Voir le document complet

18

IL-7-adjuvanted vaginal vaccine elicits strong mucosal immune responses in non-human primates

IL-7-adjuvanted vaginal vaccine elicits strong mucosal immune responses in non-human primates

... HAL Id: hal-03000444 https://hal.archives-ouvertes.fr/hal-03000444 Preprint submitted on 11 Nov 2020 HAL is a multi-disciplinary open access archive for the deposit and dissemination of sci- entific research documents, ... Voir le document complet

34

Epigenetic Mechanisms of Resistance to Immune Checkpoint Inhibitors

Epigenetic Mechanisms of Resistance to Immune Checkpoint Inhibitors

... used to treat melanoma, with very encouraging results, ICIs have been tested in many other tumor types with demonstrated clinical efficacy [ 2 ...lasting responses that translate into survival ... Voir le document complet

31

Role of DC-SIGN in Lassa Virus Entry into Human Dendritic Cells

Role of DC-SIGN in Lassa Virus Entry into Human Dendritic Cells

... DC-SIGN in MDDC correlates with enhanced LASV ...susceptible to infection with different LASV isolates and that productive infection causes virus-induced perturbation of their ... Voir le document complet

12

The Flavonoid Isoquercitrin Precludes Initiation of Zika Virus Infection in Human Cells

The Flavonoid Isoquercitrin Precludes Initiation of Zika Virus Infection in Human Cells

... epidemics in South Pacific islands and Americas due to ZIKV association with severe damage to fetal brain development and neurological complications in adult ...undertaken to identify ... Voir le document complet

14

The epigenetic regulator RINF (CXXC5) maintains SMAD7 expression in human immature erythroid cells and sustains red blood cells expansion.

The epigenetic regulator RINF (CXXC5) maintains SMAD7 expression in human immature erythroid cells and sustains red blood cells expansion.

... hematopoietic cells. Mononuclear cells were isolated from cord blood (CRB Saint-Louis Hospital, Paris) or adult bone marrow donors with written informed consent for research use, in accordance with ... Voir le document complet

59

Studying the Immune Synapse in HIV-1 Infection.

Studying the Immune Synapse in HIV-1 Infection.

... scholar in the Pasteur -­‐ Paris University (PPU) International PhD program and is funded by the People Programme (Marie Curie Actions) of the European Union’s Seventh Framework Programme FP7/2007-­‐2013/ under ... Voir le document complet

14

Dendritic cell differentiation and immune tolerance to insulin-related peptides in Igf2-deficient mice

Dendritic cell differentiation and immune tolerance to insulin-related peptides in Igf2-deficient mice

... decided in a second step to investigate the effect of Igf2 deficiency on the maturation and function of DC, the most potent APC (22) implicated in polarization of the immune response, ...iDC ... Voir le document complet

7

Dynamic changes in gene expression during human early embryo development: from fundamental aspects to clinical applications.

Dynamic changes in gene expression during human early embryo development: from fundamental aspects to clinical applications.

... upregulated in GV and 2,000 in MII oocytes (Cui et ...signalling in mature MII oocytes. The focus of our previously published study was to apply a microarray approach to identify new ... Voir le document complet

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