[PDF] Top 20 DNA Methylation and Chromatin: Role(s) of Methyl-CpG-Binding Protein ZBTB38
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DNA Methylation and Chromatin: Role(s) of Methyl-CpG-Binding Protein ZBTB38
... ZNF7 binding onto methylated sequences involves an meC-lysine-G triad in ...(ZNF3-5 and ZNF6-10) in the ZBTB38 protein bind methyl-CpG consensus sequences in ...by ... Voir le document complet
6
DNA methylation in an intron of the IBM1 histone demethylase gene stabilizes chromatin modification patterns
... intronic methylation may promote IBM1-L accumulation. First, DNA methylation may prevent premature transcription termination by obscuring transcription termination ...Indeed, DNA ... Voir le document complet
13
Specific binding of the methyl binding domain protein 2 at the BRCA1-NBR2 locus
... France and 1 Laboratory of Molecular Embryology, NIH/NICHD, Bethesda, MD, USA Received April 15, 2005; Revised and Accepted July 5, 2005 ABSTRACT The methyl-CpG binding domain ... Voir le document complet
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en fr The Methyl-CpG-Binding Domain Protein 2 (MBD2) : a specific interpret of methylated loci in cancer cells Spécificité de liaison et de répression de la « Methyl-CpG-Binding Domain protein 2 » (MBD2) : identification de gènes cibles impliqués dans les cancers
... the methylation status of the hTERT CpG island had led to a ...this CpG island was found unmethylated while the gene was transcriptionally ...most of cancer cells, this region was ... Voir le document complet
358
en fr The Methyl-CpG Binding Domain protein 2 (MBD2), a DNA methylation-dependent transcriptional repressor : identification and caracterization of MBD2 targets by genome-wide approach Étude systémique des cibles génomiques de la methyl-CpG binding domain protein 2 (MBD2), un répresseur transcriptionnel dépendant de la méthylation de l'ADN : évolution de la distribution de MBD2 dans un modèle syngénique de progression tumorale mammaire
... first protein able to associate methylated CpGs, independently of DNA sequences, was identified over 15 years ago and called MeCP2 ...a protein family of 5 members, including ... Voir le document complet
302
DNA Methylation in Rice and Relevance for Breeding
... perturbation of the methylome lead to developmental phenotypes and some mutant combination cannot be recovered due to lethality [ 71 ...Establishment of De Novo DNA Methylation TEs are ... Voir le document complet
14
The RBBP6/ZBTB38/MCM10 Axis Regulates DNA Replication and Common Fragile Site Stability
... Depletion of the Transcriptional Repressor ZBTB38 We previously conducted a yeast two-hybrid screen to identify possible interactors of RBBP6 ( Chibi et ...any of these candidates was required ... Voir le document complet
14
Convergence of DNA methylation and phosphorothioation epigenetics in bacterial genomes
... A methylation and phosphorothioation (PT), in which sulfur re- places a nonbridging oxygen in the DNA ...analysis of DNA from Escherichia coli B7A and Salmonella enterica serovar ... Voir le document complet
7
Perinatal high methyl donor alters gene expression in IGF system in male offspring without altering DNA methylation
... mating, and through- out gestation and lactation (six females per ...subset of pups was sacrificed and litters were culled to eight pups per dam (four males and four ...subset of ... Voir le document complet
18
Spectral editing of intra- and inter-chain methyl–methyl NOEs in protein complexes
... Plevin and W. Hoyer for advice and stimulating discussions, Drs ...clones of Prefoldin. This work used the high field NMR and isotopic labeling facilities at the Grenoble Instruct-ERIC Center ... Voir le document complet
15
Role of DNA methylation in INK4a-ARF-INK4b locus expression in breast cancer
... % ) 21967750 21970750 21973750 21976750 21979750 21982750 21985750 21988750 21991750 21994750 21997750 22000750 22003750 22006750 22009750 MeDIP-qPCR : Percentage of methylation on different parts of ... Voir le document complet
1
Histone H4K20 methylation mediated chromatin compaction threshold ensures genome integrity by limiting DNA replication licensing
... Jørgensen and C. Colding for assistance in the early stages of the project and to Yasuko Antoku and Kasper Nørskov Kragh for immuno fluorescence analysis ...Sauder and Vesna Oliveri for ... Voir le document complet
12
Chromatin Dynamics upon DNA Damage
... Most of the studies on chromatin mobility are based on the analysis of MSD curves calculated from the trajectories of fluorescently labeled chromatin ...studied, and the type ... Voir le document complet
22
Post-transcriptional regulation during spermatogenesis : Role of the RNA-Binding Protein HuR
... microRNAs and small interfering RNAs RNA interference (RNAi) and microRNA (miRNA) pathways are evolutionarily conserved control mechanisms that use RNA molecules to inhibit gene expression at the level ... Voir le document complet
229
Complex Chromatin Motions for DNA Repair
... (IR), and detecting repair sites using fluorescent-tagged HR components (Figure ...Miné-Hattab and Rothstein, 2012 ; Chiolo et ...advantage of inducing DSBs with IR, relative to using chemical ... Voir le document complet
17
The <em>Escherichia coli</em> colibactin resistance protein ClbS is a novel DNA binding protein that protects DNA from nucleolytic degradation
... Analysis of Molecular Interactions (University of Ljubljana, ...biotinylated DNA for immobilization on the streptavidin sensor chip, plasmid pJBPL-A was used as a matrix DNA to amplify the 403 ... Voir le document complet
6
Differential Expression of Genes and DNA Methylation associated with Prenatal Protein Undernutrition by Albumen Removal in an avian model
... weight and reproductive performance have been demonstrated in the chicken model of prenatal protein undernutrition by albumen ...Introduction of such persistent alterations in phenotype ... Voir le document complet
12
Chromatin insulator factors involved in long-range DNA interactions and their role in the folding of the Drosophila genome
... Structure of the CP190-BTB/POZ domain Overall, the FCCS data strongly suggest that the BTB/POZ domain of CP190 is involved in the direct protein-protein interactions required for the ... Voir le document complet
18
Competition by inhibitory oligonucleotides prevents binding of CpG to C-terminal TLR9
... block CpG binding to C-terminal TLR9, or to significantly decrease activation by CpG ODN at suboptimal and physiologically relevant concentrations ...spite of the reported potential ... Voir le document complet
15
Role of DNA methylation in expression control of the IKZF3-GSDMA region in human epithelial cells
... their binding to DNA leading to changes in ...increased methylation in promoter or enhancer regions leads to gene silencing/ down-regulation [ 25 – 27 ...consequences of methylation ... Voir le document complet
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